Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   EQH18_RS00860 Genome accession   NZ_CP035262
Coordinates   166592..167032 (-) Length   146 a.a.
NCBI ID   WP_000861956.1    Uniprot ID   A0A0H2UNA2
Organism   Streptococcus pneumoniae strain TVO_1901923     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 161592..172032
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH18_RS00835 (EQH18_00875) - 161853..163139 (+) 1287 WP_000278879.1 response regulator transcription factor -
  EQH18_RS00840 (EQH18_00880) - 163191..163724 (+) 534 WP_000729029.1 hypothetical protein -
  EQH18_RS00845 (EQH18_00885) nrdI 163802..164272 (+) 471 WP_000849621.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  EQH18_RS00850 (EQH18_00895) - 164565..165827 (-) 1263 WP_000075789.1 NRAMP family divalent metal transporter -
  EQH18_RS00855 (EQH18_00900) - 166137..166595 (-) 459 WP_000745054.1 DUF3021 domain-containing protein -
  EQH18_RS00860 (EQH18_00905) brsR 166592..167032 (-) 441 WP_000861956.1 LytTR family DNA-binding domain-containing protein Regulator
  EQH18_RS10650 - 167120..167245 (-) 126 WP_001813544.1 hypothetical protein -
  EQH18_RS00865 (EQH18_00915) hexB 167388..169337 (+) 1950 WP_000018169.1 DNA mismatch repair endonuclease MutL Machinery gene
  EQH18_RS00870 (EQH18_00920) ribE 169662..170129 (-) 468 WP_001099502.1 6,7-dimethyl-8-ribityllumazine synthase -
  EQH18_RS00875 (EQH18_00925) - 170130..171335 (-) 1206 WP_001842537.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II -
  EQH18_RS00880 (EQH18_00930) ribE 171355..171990 (-) 636 WP_000493842.1 riboflavin synthase -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17183.84 Da        Isoelectric Point: 5.3783

>NTDB_id=297635 EQH18_RS00860 WP_000861956.1 166592..167032(-) (brsR) [Streptococcus pneumoniae strain TVO_1901923]
MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIKGKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSI
DLRLYQVLKLLPTNFIQISQSEIINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=297635 EQH18_RS00860 WP_000861956.1 166592..167032(-) (brsR) [Streptococcus pneumoniae strain TVO_1901923]
ATGAAAGTAGAACTACAGATTAGTGAGACTTACGAGGAGGAAAAGCTGATTGTCCAAGCACCTCAAGAAACCGAAAAAGT
CCAGAAAGTCATCGAGTTCGCAGAAAATCTGGACCAAAGAGAAAAAATCAAAGGAAAAATCGATGATCAGGTCTATCTAG
TTGAGATTGGCAAGATTCAGCGCTTCTATATCGAGAATCGGAAGGTTCTAGCAGAAACCGCGAGTCAGACCTACAGCATT
GATTTGCGACTCTATCAGGTTCTTAAACTCTTGCCAACCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCGA
TTCCATCTCTCACCTCAAGCTCACGCCAAACGGTCTGGTAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTATCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(50-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UNA2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.054

100

0.363