Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   SPJ_RS00955 Genome accession   NC_012466
Coordinates   172779..173219 (-) Length   146 a.a.
NCBI ID   WP_000861968.1    Uniprot ID   -
Organism   Streptococcus pneumoniae JJA     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 167779..178219
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPJ_RS00930 (SPJ_0185) - 168040..169326 (+) 1287 WP_000278869.1 response regulator transcription factor -
  SPJ_RS00935 (SPJ_0186) - 169378..169911 (+) 534 WP_000729029.1 hypothetical protein -
  SPJ_RS00940 (SPJ_0187) nrdI 169989..170459 (+) 471 WP_000849621.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  SPJ_RS00945 (SPJ_0188) - 170752..172014 (-) 1263 WP_000075789.1 NRAMP family divalent metal transporter -
  SPJ_RS00950 (SPJ_0189) - 172324..172782 (-) 459 WP_000745054.1 DUF3021 domain-containing protein -
  SPJ_RS00955 (SPJ_0190) brsR 172779..173219 (-) 441 WP_000861968.1 LytTR family DNA-binding domain-containing protein Regulator
  SPJ_RS13520 - 173307..173432 (-) 126 WP_001822433.1 hypothetical protein -
  SPJ_RS00960 (SPJ_0191) hexB 173575..175524 (+) 1950 WP_000018156.1 DNA mismatch repair endonuclease MutL Machinery gene
  SPJ_RS00965 (SPJ_0192) ribE 175849..176316 (-) 468 WP_001099502.1 6,7-dimethyl-8-ribityllumazine synthase -
  SPJ_RS00970 (SPJ_0193) - 176317..177522 (-) 1206 WP_000456639.1 bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II -
  SPJ_RS00975 (SPJ_0194) ribE 177542..178177 (-) 636 WP_000493841.1 riboflavin synthase -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17137.81 Da        Isoelectric Point: 5.9797

>NTDB_id=29735 SPJ_RS00955 WP_000861968.1 172779..173219(-) (brsR) [Streptococcus pneumoniae JJA]
MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIKGKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSI
DLRLYQVLKLLPTNFIQISQSEIINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=29735 SPJ_RS00955 WP_000861968.1 172779..173219(-) (brsR) [Streptococcus pneumoniae JJA]
ATGAAAGTAGAATTACAGATTAGTGAGACTTACGAGGAGGAAAAGCTGATTGTCCAAGCACCTCAGCCGACAGATAAAGT
TCAGAAAGTCATCGAGTTCGCAGAAAATCTGGACCAAAGAGAAAAAATCAAAGGGAAAATCGATGATCAGGTCTATCTAG
TTGAGATTGGCAAGATTCAGCGCTTCTATATCGAGAATCGGAAGGTTCTAGCAGAAACCGCGAGTCAGACCTACAGCATT
GATTTGCGACTCTATCAGGTTCTTAAACTCTTGCCAACCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCGA
TTCCATCTCTCACCTCAAGCTCACGCCAAACGGTCTGGTAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTATCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(50-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.054

100

0.363

Multiple sequence alignment