Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexA   Type   Machinery gene
Locus tag   SUB_RS08875 Genome accession   NC_012004
Coordinates   1773067..1775610 (-) Length   847 a.a.
NCBI ID   WP_015912076.1    Uniprot ID   B9DW73
Organism   Streptococcus uberis 0140J     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1768067..1780610
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SUB_RS08860 (SUB1783) hexB 1769181..1771163 (-) 1983 WP_015912073.1 DNA mismatch repair endonuclease MutL Machinery gene
  SUB_RS08865 (SUB1784) - 1771381..1771890 (+) 510 WP_015912074.1 hypothetical protein -
  SUB_RS08870 (SUB1785) - 1772117..1772977 (+) 861 WP_015912075.1 staphylokinase domain-containing protein -
  SUB_RS08875 (SUB1786) hexA 1773067..1775610 (-) 2544 WP_015912076.1 DNA mismatch repair protein MutS Machinery gene
  SUB_RS08880 (SUB1787) - 1775597..1775950 (-) 354 WP_015912077.1 YlbF family regulator -
  SUB_RS08885 (SUB1788) argR 1775947..1776384 (-) 438 WP_015912078.1 arginine repressor -
  SUB_RS08890 (SUB1789) argS 1776668..1778356 (+) 1689 WP_015912079.1 arginine--tRNA ligase -
  SUB_RS08895 (SUB1790) - 1778401..1779279 (-) 879 WP_015912080.1 YitT family protein -
  SUB_RS08900 (SUB1791) - 1779326..1780210 (-) 885 WP_015912081.1 YitT family protein -

Sequence

Protein


Download         Length: 847 a.a.        Molecular weight: 95398.04 Da        Isoelectric Point: 5.3848

>NTDB_id=29722 SUB_RS08875 WP_015912076.1 1773067..1775610(-) (hexA) [Streptococcus uberis 0140J]
MADSKISPGMQQYLDIKAQYPDAFLLFRMGDFYELFYDDAVKAAQLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDILI
ELGYKVAIAEQMEDPKKAVGVVKREVVQVITPGTVVDSAKPNSSNNFLIAIDFDGSHYGLSYMDLVTGEFFATTLSDFMS
VCGEILNLKAKEVVIGFEITAEQEEQLQKQFRLLLSYEQEIYTDDTLINPNLSQVEKNVAGKLLQYVHQTQMRELSHLQE
LIHYDIKDYLQMSYATKSSLDLIENARTKKKHGSLYWLLDETKTAMGMRLLKTWIDRPLISKQAISERQNIVETFLESFI
ERSDLADSLKGVYDIERLSSRVSFGKVNPKDLLQLGHTLSQVPYIKAVLEAINSPHLSKVIATIDPIPELESLIHSAIDP
DAPATISEGSIIKTGFDQRLDHYRKVMKEGTGWIADIEMKERQASGINNLKIDYNKKDGYYFHVTNSNLSLVPDHFFRKA
TLKNSERYGTAELAKIEGQMLEAREESAQLEYDIFMRIREKVETYIDRLQTLAKAIATVDVLQGLAYVAEKNHYVRPEFA
SQKVITIQNGRHAVVEKVMGVQEYIPNTIQFNQNTSIQLITGPNMSGKSTYMRQLALTVIMAQMGSYVAADYAKLPIFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIQRASHDSLIIFDELGRGTATYDGMALAQSIIEHIHNRIGAITLFATHYHEL
TSLSEELGHLKNVHVAILERDGEVTFLHKIAEGPADKSYGIHVAKIAGLPGSLLSRADNILKQLESHSKDFIIKDNSQQS
EENEPLNLLTEETSSQDIINRLKEVDVMNMTPMEAMTVLFDLKKKIK

Nucleotide


Download         Length: 2544 bp        

>NTDB_id=29722 SUB_RS08875 WP_015912076.1 1773067..1775610(-) (hexA) [Streptococcus uberis 0140J]
ATGGCAGATTCTAAAATTTCTCCTGGAATGCAACAGTATCTGGATATAAAAGCTCAATATCCAGATGCTTTTTTGCTTTT
TAGGATGGGTGATTTTTATGAATTATTTTATGATGATGCTGTAAAAGCTGCACAACTATTAGAAATTGGCTTAACGAGTC
GCAATAAGAATGCGGAAAATCCAATACCGATGGCAGGTGTCCCTCATCACTCTGCTCAGCAATATATTGATATTCTCATT
GAATTAGGCTATAAGGTTGCTATTGCAGAACAAATGGAAGATCCAAAGAAAGCTGTTGGGGTTGTTAAGCGTGAGGTAGT
TCAAGTAATCACGCCTGGTACAGTTGTCGATTCAGCTAAGCCAAATAGTTCCAATAATTTTTTGATTGCAATAGATTTTG
ACGGCAGTCACTATGGATTATCCTACATGGATTTGGTAACGGGAGAATTTTTTGCGACTACCTTGAGTGATTTTATGAGT
GTTTGCGGTGAAATCTTGAATTTAAAAGCAAAAGAAGTGGTTATTGGTTTTGAAATCACTGCTGAACAAGAAGAACAATT
ACAAAAACAGTTTCGTTTATTGCTATCTTATGAGCAAGAAATTTACACAGATGACACTCTCATTAATCCTAATCTATCAC
AAGTGGAAAAGAATGTTGCAGGAAAATTATTACAGTATGTGCATCAGACGCAAATGCGCGAGTTATCCCACCTTCAAGAA
CTCATACACTATGATATCAAGGATTATTTACAAATGTCATATGCGACTAAGTCAAGTCTTGATTTAATTGAGAATGCCAG
AACGAAGAAGAAACATGGAAGTCTCTATTGGCTACTTGACGAAACAAAGACAGCAATGGGGATGCGACTGTTAAAGACAT
GGATTGACAGACCGTTGATTTCAAAGCAAGCTATTAGTGAGCGTCAAAACATTGTAGAAACTTTTTTAGAGTCATTTATT
GAAAGGTCTGATTTAGCAGACAGTCTAAAAGGTGTCTACGATATTGAAAGGTTGTCTAGTCGAGTTTCCTTTGGCAAAGT
TAATCCAAAAGATCTTTTACAACTAGGCCATACTCTAAGTCAAGTACCTTATATTAAAGCTGTATTGGAAGCTATCAACA
GTCCGCATTTATCTAAAGTAATTGCAACCATCGATCCGATACCAGAACTAGAAAGTTTGATTCATTCAGCTATTGACCCA
GACGCACCAGCTACCATTAGTGAAGGCAGTATTATTAAAACTGGTTTTGATCAGCGCTTGGACCATTACCGAAAAGTGAT
GAAAGAAGGCACGGGTTGGATTGCTGATATTGAAATGAAAGAGCGTCAAGCCAGTGGCATCAATAACCTTAAAATTGATT
ACAATAAAAAAGATGGTTACTACTTTCATGTCACAAACTCCAACCTTTCCTTAGTCCCTGACCATTTTTTTAGAAAAGCT
ACGCTAAAAAATTCAGAACGATATGGCACAGCAGAATTAGCTAAAATAGAAGGTCAGATGCTTGAAGCGCGTGAAGAATC
AGCTCAATTAGAATATGATATCTTCATGCGAATCAGAGAGAAAGTGGAAACCTACATTGACAGATTACAGACTTTAGCTA
AAGCAATAGCTACAGTAGATGTATTACAAGGTTTAGCCTATGTTGCTGAGAAAAATCATTATGTCAGACCAGAATTTGCC
TCTCAAAAAGTCATTACGATTCAAAATGGAAGACATGCCGTTGTCGAAAAGGTCATGGGAGTTCAAGAGTACATTCCAAA
TACTATCCAATTTAATCAAAATACGTCTATCCAATTGATAACTGGCCCAAATATGAGTGGGAAATCGACTTATATGAGAC
AATTGGCTTTAACTGTTATCATGGCTCAAATGGGATCTTATGTAGCAGCTGACTACGCCAAATTACCAATCTTTGATGCT
ATCTTTACGCGTATTGGAGCAGCAGATGACTTAATATCTGGCCAATCAACATTTATGGTTGAAATGATGGAAGCTAACCA
AGCAATTCAAAGAGCTAGTCACGATAGTCTCATCATCTTTGATGAACTTGGACGTGGAACAGCCACTTATGATGGTATGG
CCCTGGCACAGTCCATCATCGAACATATTCATAACAGAATAGGAGCCATTACTCTTTTTGCTACCCACTATCATGAGTTG
ACTTCCTTGTCGGAAGAACTTGGGCACCTCAAGAATGTTCATGTAGCTATTTTAGAAAGAGATGGTGAAGTAACCTTTCT
TCATAAAATTGCGGAAGGCCCAGCCGATAAATCATATGGTATCCATGTGGCAAAAATTGCAGGCTTACCAGGCTCTTTGC
TGAGCCGAGCAGATAATATTTTAAAACAGTTGGAAAGCCATTCCAAGGATTTTATCATAAAAGATAATTCGCAACAATCA
GAAGAAAATGAGCCATTAAATTTATTGACGGAGGAGACTTCCTCTCAAGATATCATTAATAGACTTAAAGAAGTAGATGT
CATGAATATGACTCCAATGGAAGCTATGACTGTTTTGTTTGATCTAAAGAAAAAAATAAAATAA

Domains

Predicted by InterProScan.

MutS domain I (MutS_I)

(8-118)

MutS family domain IV (MutS_IV)

(415-506)

MutS domain II (MutS_II)

(126-239)

MutS domain V (MutS_V)

(599-785)

MutS domain III (MutS_III)

(256-546)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B9DW73

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexA Streptococcus pneumoniae R6

69.976

99.882

0.699
  mutS Pseudomonas stutzeri strain ATCC 17587

36.279

100

0.368