Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexA   Type   Machinery gene
Locus tag   EQH31_RS10180 Genome accession   NZ_CP035249
Coordinates   1967116..1969650 (-) Length   844 a.a.
NCBI ID   WP_000963661.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901938     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1962116..1974650
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH31_RS10165 (EQH31_10780) patB 1962718..1964484 (-) 1767 WP_000859851.1 multidrug efflux ABC transporter subunit PatB -
  EQH31_RS10170 - 1964676..1965125 (+) 450 Protein_1985 transposase -
  EQH31_RS10175 (EQH31_10790) patA 1965275..1966969 (-) 1695 WP_000908152.1 multidrug efflux ABC transporter subunit PatA -
  EQH31_RS10180 (EQH31_10795) hexA 1967116..1969650 (-) 2535 WP_000963661.1 DNA mismatch repair protein MutS Machinery gene
  EQH31_RS10185 (EQH31_10800) argR 1969701..1970147 (-) 447 WP_001231472.1 arginine repressor -
  EQH31_RS10190 (EQH31_10805) argS 1970283..1971974 (+) 1692 WP_001092701.1 arginine--tRNA ligase -
  EQH31_RS10195 (EQH31_10810) - 1972310..1972867 (-) 558 Protein_1990 transposase family protein -
  EQH31_RS10200 (EQH31_10815) - 1972853..1973338 (+) 486 WP_000035500.1 cupin domain-containing protein -
  EQH31_RS10205 (EQH31_10820) - 1973422..1974129 (+) 708 WP_000166475.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 844 a.a.        Molecular weight: 94806.38 Da        Isoelectric Point: 4.9137

>NTDB_id=296520 EQH31_RS10180 WP_000963661.1 1967116..1969650(-) (hexA) [Streptococcus pneumoniae strain TVO_1901938]
MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAAQILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLI
EQGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKLDSQNNFLVAIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
VCGEIRNLKAREVVLGYDLSEEEEQILSCQMNLVLSYEKESFEDLHLLDLRLATVEQTASSKLLQYVHRTQMRELNHLKP
VIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLFWLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFF
ERSDLTDSLKGVYDIERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPALAYLIAQLDAIPELESLISAAIAP
EAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTLKIDYNKKDGYYFHVTNSQLGNVPAHFFRKA
TLKNSERFGTEELARIEGDMLEAREKSANLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFG
DDSQIDIRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLITGPNMSGKSTYMRQLAMTAVMAQLGSYVPAESAHLPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDELGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHEL
TSLESSLQHLVNVHVATLEQDGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTENPPPMRQTSA
VTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL

Nucleotide


Download         Length: 2535 bp        

>NTDB_id=296520 EQH31_RS10180 WP_000963661.1 1967116..1969650(-) (hexA) [Streptococcus pneumoniae strain TVO_1901938]
ATGGCGATAGAAAAGCTATCACCCGGCATGCAACAGTATGTGGATATTAAAAAGCAATATCCAGATGCTTTTTTGCTCTT
TCGGATGGGTGATTTTTATGAATTATTTTATGAGGATGCGGTCAATGCTGCGCAGATTCTGGAAATTTCCTTAACGAGTC
GCAACAAGAATGCCGACAATCCGATCCCTATGGCGGGTGTTCCCTATCATTCTGCCCAACAGTATATCGATGTCTTGATT
GAGCAGGGTTATAAGGTGGCTATCGCAGAGCAGATGGAAGATCCTAAACAAGCAGTTGGGGTTGTTAAACGAGAGGTTGT
TCAGGTCATTACGCCAGGGACAGTGGTCGATAGCAGTAAGCTGGACAGTCAGAATAATTTTTTGGTTGCCATAGACCGCG
AAGGCAATCAATTTGGCCTAGCTTATATGGATTTGGTGACGGGTGACTTTTATGTGACAGGTCTTTTGGATTTCACGCTG
GTTTGTGGGGAAATCCGTAACCTCAAGGCTCGAGAAGTGGTGTTGGGTTATGACTTGTCTGAGGAAGAAGAACAAATCCT
CAGCTGCCAGATGAATCTGGTACTCTCTTATGAAAAAGAAAGCTTTGAAGACCTTCATTTATTGGATTTGCGATTGGCAA
CGGTGGAGCAAACGGCATCTAGTAAGCTGCTCCAGTATGTTCATCGGACTCAGATGAGGGAATTGAACCACCTCAAACCT
GTTATCCGCTACGAAATTAAGGATTTCTTGCAGATGGATTATGCGACCAAGGCTAGTCTGGATTTGGTTGAGAATGCTCG
CTCAGGTAAGAAACAAGGCAGTCTTTTCTGGCTTTTGGATGAAACCAAAACGGCTATGGGGATGCGTCTCTTGCGTTCTT
GGATTCATCGCCCCTTGATTGATAAGGAACGAATCGTCCAACGTCAAGAAGTAGTGCAGGTCTTTCTCGACCATTTCTTT
GAGCGTAGTGACTTGACAGACAGTCTCAAGGGTGTTTATGACATTGAGCGCTTGGCTAGTCGTGTTTCTTTTGGCAAAAC
CAATCCAAAGGATCTCTTGCAGTTGGCGACTACCTTGTCTAGTGTGCCACGGATTCGTGCGATTTTAGAAGGGATGGAGC
AACCTGCTCTAGCCTATCTCATCGCACAACTGGATGCAATCCCTGAGTTGGAGAGTTTGATTAGCGCAGCGATTGCTCCT
GAAGCTCCTCATGTGATTACAGATGGGGGAATTATCCGGACTGGATTTGATGAGACTTTAGACAAGTATCGTTGCGTTCT
CAGAGAAGGGACTAGCTGGATTGCTGAGATTGAGGCTAAGGAGCGAGAAAACTCTGGTATCAGCACGCTCAAGATTGACT
ACAATAAAAAGGATGGCTACTATTTTCATGTGACCAATTCGCAACTGGGAAATGTGCCAGCCCACTTTTTCCGCAAGGCG
ACGCTGAAAAACTCAGAACGCTTTGGAACCGAAGAATTAGCCCGTATCGAGGGAGATATGCTTGAGGCGCGTGAGAAGTC
AGCCAACCTCGAATACGAAATATTTATGCGCATTCGTGAAGAGGTCGGCAAGTACATCCAGCGTTTACAAGCTTTAGCCC
AAGGAATTGCGACGGTTGATGTCTTACAGAGTCTGGCGGTTGTGGCTGAAACCCAGCATTTGATTCGACCTGAGTTTGGT
GACGATTCACAAATTGATATCCGGAAAGGGCGCCATGCTGTCGTTGAAAAGGTTATGGGGGCTCAGACCTATATTCCAAA
TACGATTCAGATGGCAGAAGATACCAGTATTCAACTGATTACAGGGCCAAACATGAGTGGGAAGTCTACCTATATGCGTC
AGTTAGCCATGACGGCGGTTATGGCCCAGCTGGGTTCCTATGTTCCTGCTGAAAGCGCCCATTTACCGATTTTTGATGCG
ATTTTTACCCGTATCGGAGCAGCAGATGACTTGGTTTCGGGTCAGTCAACCTTTATGGTGGAGATGATGGAGGCCAATAA
TGCCATTTCGCATGCGACCAAGAACTCTCTCATTCTCTTTGATGAATTGGGACGTGGAACTGCAACTTATGACGGGATGG
CTCTTGCTCAGTCCATCATCGAATATATCCATGAGCACATCGGAGCTAAGACCCTCTTTGCGACCCACTACCATGAGTTG
ACTAGTCTGGAGTCTAGTTTACAACACTTGGTCAATGTCCACGTGGCAACTTTGGAGCAGGATGGGCAGGTCACCTTCCT
TCACAAGATTGAACCGGGACCAGCTGATAAATCCTACGGTATCCATGTTGCCAAGATTGCTGGCTTGCCAGCAGACCTTT
TAGCAAGGGCGGATAAGATTTTGACTCAGCTAGAGAATCAAGGAACAGAGAATCCTCCTCCCATGAGACAAACTAGTGCT
GTCACTGAACAGATTTCACTCTTTGATAGGGCAGAAGAGCATCCTATCCTAGCAGAATTAGCTAAACTGGATGTGTATAA
TATGACACCTATGCAGGTTATGAATGTCTTAGTAGAGTTAAAACAGAAACTATAA

Domains

Predicted by InterProScan.

MutS domain III (MutS_III)

(256-546)

MutS family domain IV (MutS_IV)

(415-505)

MutS domain I (MutS_I)

(8-118)

MutS domain II (MutS_II)

(126-239)

MutS domain V (MutS_V)

(599-785)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexA Streptococcus pneumoniae R6

99.289

100

0.993
  mutS Pseudomonas stutzeri strain ATCC 17587

36.725

100

0.372