Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   EQH32_RS05520 Genome accession   NZ_CP035248
Coordinates   1086235..1086699 (-) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus pneumoniae strain TVO_1901939     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1081235..1091699
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH32_RS05500 (EQH32_05785) - 1082186..1083154 (-) 969 WP_000105360.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  EQH32_RS05505 (EQH32_05790) pdrM 1083308..1084669 (-) 1362 WP_000278533.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  EQH32_RS05510 (EQH32_05795) - 1084680..1084940 (-) 261 WP_001105925.1 hypothetical protein -
  EQH32_RS05515 (EQH32_05800) - 1084954..1086222 (-) 1269 WP_000924490.1 dihydroorotase -
  EQH32_RS05520 (EQH32_05805) mutX 1086235..1086699 (-) 465 WP_001135768.1 8-oxo-dGTP diphosphatase Machinery gene
  EQH32_RS05525 (EQH32_05810) - 1086709..1087362 (-) 654 WP_000401326.1 uracil-DNA glycosylase -
  EQH32_RS05530 (EQH32_05815) - 1087498..1088100 (-) 603 WP_001812270.1 hypothetical protein -
  EQH32_RS05535 (EQH32_05820) - 1088158..1088871 (-) 714 WP_000499429.1 YjjG family noncanonical pyrimidine nucleotidase -
  EQH32_RS05540 (EQH32_05825) - 1089287..1089505 (-) 219 Protein_1109 PTS mannose family transporter subunit IIA -
  EQH32_RS10850 - 1089505..1089579 (-) 75 Protein_1110 dihydroxyacetone kinase subunit L -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=296346 EQH32_RS05520 WP_001135768.1 1086235..1086699(-) (mutX) [Streptococcus pneumoniae strain TVO_1901939]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=296346 EQH32_RS05520 WP_001135768.1 1086235..1086699(-) (mutX) [Streptococcus pneumoniae strain TVO_1901939]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGCGCGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGACGCTAGAATGGGTTCC
CTATGACGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987