Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilA   Type   Machinery gene
Locus tag   NMCC_RS00235 Genome accession   NC_010120
Coordinates   40735..42000 (+) Length   421 a.a.
NCBI ID   WP_012221114.1    Uniprot ID   -
Organism   Neisseria meningitidis 053442     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 35735..47000
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMCC_RS00215 (NMCC_0042) - 36466..37467 (+) 1002 WP_002220087.1 thiamine ABC transporter substrate-binding protein -
  NMCC_RS00220 (NMCC_0043) - 37561..38409 (+) 849 WP_002215243.1 mechanosensitive ion channel family protein -
  NMCC_RS00225 (NMCC_0044) - 38435..38920 (+) 486 WP_002221794.1 CinA family protein -
  NMCC_RS00230 (NMCC_0045) msrAB 39022..40590 (-) 1569 WP_002216163.1 bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB -
  NMCC_RS00235 (NMCC_0046) pilA 40735..42000 (+) 1266 WP_012221114.1 signal recognition particle-docking protein FtsY Machinery gene
  NMCC_RS00240 (NMCC_0047) - 42941..43225 (+) 285 WP_002216166.1 GIY-YIG nuclease family protein -

Sequence

Protein


Download         Length: 421 a.a.        Molecular weight: 45175.42 Da        Isoelectric Point: 4.5275

>NTDB_id=29627 NMCC_RS00235 WP_012221114.1 40735..42000(+) (pilA) [Neisseria meningitidis 053442]
MFSFFRRKKKQETPALEEAQIQETAAKAESETDQVIENIKEDAESLAESVKGQVESAVETVSGAVEQVKETVAEMLSEAE
EAAEKAAEQVEAAKEAVAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLTKSRDKMAKSLAGVFGGGQIDEDLYEELET
VLITSDMGMEATEYLMKDVRDRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGK
LAKYFQAQGKSVLLAAGDTFRAAAREQLQAWGERNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHL
MEEIKKVKRVLQKAMPDAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGV
GEGIDDLRPFDARAFVDALLD

Nucleotide


Download         Length: 1266 bp        

>NTDB_id=29627 NMCC_RS00235 WP_012221114.1 40735..42000(+) (pilA) [Neisseria meningitidis 053442]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACGCCGGCTCTCGAGGAGGCTCAAATTCAGGAAACCGCAGCAAA
AGCAGAGTCCGAAACCGATCAAGTAATTGAAAATATTAAAGAAGATGCTGAATCTTTAGCAGAAAGCGTCAAAGGGCAGG
TCGAATCTGCCGTTGAAACCGTCAGCGGTGCGGTTGAACAGGTAAAGGAAACCGTTGCCGAGATGCTGTCTGAAGCAGAG
GAAGCGGCGGAAAAAGCAGCGGAACAAGTCGAAGCGGCAAAAGAAGCCGTTGCCGAAACCGTCGGCGAGGCTGTCGGGCA
AGTTCAAGAAGCCGTTGCGACAACTGAAGAACACAAGCTCGGTTGGGCGGCGCGTTTGAAACAAGGTTTGACCAAATCGC
GCGACAAAATGGCGAAATCGCTGGCGGGCGTGTTCGGCGGTGGACAAATCGACGAAGATTTGTACGAAGAGCTGGAAACC
GTGCTGATTACCAGCGATATGGGCATGGAAGCCACCGAATACCTGATGAAAGACGTGCGCGACCGCGTCAGCCTCAAAGG
GCTGAAAGACGGCAACGAATTGCGCGGCGCGTTGAAAGAAGCCTTGTACGACCTGATTAAGCCTCTGGAGAAACCTTTGG
TTTTGCCCGAAACCAAAGAGCCGTTTGTCATCATGCTTGCCGGCATCAACGGCGCGGGCAAAACCACGTCTATCGGCAAA
CTCGCCAAATATTTCCAAGCGCAGGGCAAATCTGTGCTGCTTGCCGCCGGCGATACTTTCCGCGCCGCCGCCCGTGAGCA
GCTTCAAGCTTGGGGCGAACGCAACAACGTAACCGTGATTTCGCAAACCACGGGCGATTCCGCCGCCGTGTGCTTCGATG
CCGTCCAAGCCGCCAAAGCGCGCGGCATCGACATCGTGCTTGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCATTTG
ATGGAAGAAATCAAAAAAGTGAAACGCGTGCTGCAAAAAGCCATGCCCGACGCGCCGCACGAAATCATCGTCGTGCTTGA
TGCCAACATCGGGCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTAGGGCTGACCGGTTTAATCGTGACCA
AACTCGACGGCACGGCAAAAGGCGGCATCCTCGCCGCGCTTGCCTCCGACCGCCCCGTCCCCGTCCGCTATATCGGCGTG
GGCGAAGGCATAGACGACCTGCGCCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

SRP54-type protein, helical bundle domain (SRP54_N)

(136-202)

SRP54-type protein, GTPase domain (SRP54)

(221-420)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilA Neisseria gonorrhoeae MS11

94.062

100

0.941

Multiple sequence alignment