Detailed information NTG0295986

Bioinformatically predicted

Overview

• Name: rexA
• Type: Machinery gene
• Locus tag: EQH35_RS05400
• Genome accession: NZ_CP035245
• Coordinates: 1049803..1053453 (+)
• Length: 1216 a.a.
• NCBI ID: WP_000767245.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901943
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 1044803..1058453

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH35_RS05375 (EQH35_05685)	-	1044928..1045374 (-)	447	WP_044811956.1	tyrosine-type recombinase/integrase	-
EQH35_RS10895 (EQH35_05690)	-	1045274..1045480 (-)	207	Protein_1082	transposase	-
EQH35_RS10900 (EQH35_05695)	-	1045587..1046102 (-)	516	Protein_1083	IS630 transposase-related protein	-
EQH35_RS05390 (EQH35_05700)	-	1046170..1046331 (+)	162	Protein_1084	diacylglycerol kinase family lipid kinase	-
EQH35_RS05395 (EQH35_05705)	rexB	1046531..1049806 (+)	3276	WP_000772360.1	ATP-dependent nuclease subunit B	Machinery gene
EQH35_RS05400 (EQH35_05710)	rexA	1049803..1053453 (+)	3651	WP_000767245.1	helicase-exonuclease AddAB subunit AddA	Machinery gene
EQH35_RS05405 (EQH35_05715)	-	1053415..1053672 (-)	258	WP_144005151.1	hypothetical protein	-
EQH35_RS05410 (EQH35_05725)	-	1053893..1055071 (+)	1179	WP_000174775.1	hypothetical protein	-

Sequence

Protein

• Length: 1216 a.a.
• Molecular weight: 140264.00 Da
• Isoelectric Point: 5.4445

>NTDB_id=295986 EQH35_RS05400 WP_000767245.1 1049803..1053453(+) (rexA) [Streptococcus pneumoniae strain TVO_1901943]
MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNILVSASAGSGKTFVMAERILDQLARGVEISQLFISTFT
VKAATELKERLEKKISKKIQETDDVELKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
NEVFHEVFEAHYQGKQKETFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNSQKWLSDSFLKGFEKADFTSEKEKLTE
QIKQALWDLESFFRYHLDNDAKEFAKAAYLENVQLILDEICSLNQESDSQAYQAVLARVVAISKEKNGRALTNASRKADL
KPLADAYNEERKTQFTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADISHYTIEILE
NFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQSIYRFRQADPQIFNEKFQRYAQNPQEGRLIL
LKENFRSSSEVLSTTNDVFERLMDQEVGEINYDNMHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMR
LVIKEILKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLDTLRVIHNPLQDYALVA
LMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMASSQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIW
KIYNDRFYYDYVGALPNGPARQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLASVAVAPPKDAVELMTIHKS
KGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIKLSIPSLTYRQNEEELQLASYSEQM
RLLYVAMTRAEKKLYLVGKGSREKLEAKQYPAAKNGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTRE
AIGELETKSPLQDSSQADNRQSDTIKEALKMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGVEIAGQGQSVG
KKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLKQVQTSQAVRDKINLDKILAFFDTVLGQEILAN
TDHLYREQPFSMLKRDQKSQEDFVVRGILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIE
KYLILLGKDEAQVVKV

Nucleotide

• Length: 3651 bp

>NTDB_id=295986 EQH35_RS05400 WP_000767245.1 1049803..1053453(+) (rexA) [Streptococcus pneumoniae strain TVO_1901943]
ATGAAGCTTATTCCCTTTTTAAGTGAGGAGGAGATTCAAAAACTGCAAGAAGCAGAAGCAAATTCGAGCAAGGAACAGAA
GAAAACTGCCGAGCAAATCGAAGCTATCTACACTTCTGGCCAGAATATCCTGGTCTCAGCATCGGCTGGTTCTGGAAAGA
CCTTTGTCATGGCAGAGCGCATTCTGGACCAATTGGCGCGTGGTGTCGAAATTTCTCAACTCTTTATCTCAACCTTTACC
GTCAAGGCTGCAACTGAACTTAAAGAACGTTTAGAGAAAAAAATCAGCAAGAAAATCCAAGAAACAGATGATGTCGAGCT
CAAACAACACTTGGGTCGCCAGTTGGCAGACCTACCCAACGCTGCCATCGGAACCATGGACTCTTTCACACAAAAATTCC
TTGGCAAACATGGTTATCTGCTTGATATTGCACCTAATTTCCGTATTTTACAAAACCAAAGCGAGCAACTTCTTCTCGAA
AACGAAGTCTTTCATGAGGTCTTTGAAGCGCATTACCAAGGTAAACAGAAAGAGACCTTTAGTCATTTGCTGAAAAACTT
TGCTGGGCGTGGCAAGGACGAACGGGGTCTGCGCCAGCAGGTCTATAAAATCTATGACTTCCTCCAATCCACCAGCAATT
CTCAAAAGTGGCTGAGTGACTCTTTCCTCAAAGGCTTTGAGAAAGCTGATTTTACCAGTGAAAAAGAAAAACTGACTGAG
CAAATCAAACAAGCCCTTTGGGATTTGGAAAGCTTTTTCCGTTACCATCTGGATAACGATGCCAAGGAGTTTGCAAAGGC
TGCCTATTTAGAAAATGTTCAGTTAATTCTGGATGAAATTTGCTCCCTAAATCAGGAGTCCGATAGTCAGGCTTATCAGG
CAGTGCTTGCGCGTGTTGTCGCCATCTCTAAGGAGAAAAACGGTCGAGCTCTGACTAATGCCAGCCGTAAGGCTGATTTG
AAGCCCCTGGCTGATGCCTACAACGAAGAGAGAAAGACCCAGTTTACTAAACTAGGACAATTATCAGACCAGATAGCGAT
TCTCGACTATCAAGAACGTTATCATGGAGACACTTGGAAACTAGCTAAAACCTTCCAATCTTTCATGAGCGATTTTGTAG
AGGCTTATCGTCAGAGAAAACGACAGGAAAATGCCTTTGAATTCGCTGATATCAGCCATTACACCATTGAGATTTTAGAA
AATTTCCCACAAGTTCGTGAGTCTTATCAGGAGCGCTTCCATGAAGTCATGGTCGATGAGTATCAGGATACCAACCATAT
TCAAGAACGGATGCTGGAATTGTTGTCTAATGGCCACAATCGCTTTATGGTGGGAGATATCAAGCAATCCATCTATCGTT
TCCGTCAGGCAGACCCGCAGATTTTCAATGAGAAATTCCAACGCTATGCGCAAAATCCTCAAGAAGGCAGGCTCATTCTC
CTCAAGGAAAATTTCCGTAGTAGTTCAGAAGTGCTGTCAACAACCAATGATGTCTTTGAACGTCTCATGGACCAAGAGGT
CGGCGAAATCAACTATGATAACATGCACCAGCTTGTTTTTGCCAATACCAAACTGACTCCCAATCCAGACAACAAGGCAG
AATTTCTCCTCTACGACAAGGACGATACAGGTGAGGAAGAAGAGAGTCAAACAGAAACGAAACTAACAGGCGAAATGCGC
TTAGTTATCAAGGAGATTCTGAAACTTCATCAAGAAAAAGGTGTTGCCTTTAAGGAAATTGCCCTTCTGACCTCCAGCCG
CAGTCGTAATGACCAGATTCTCCTCGCCCTGTCTGAGTACGGAATTCCTGTCAAAACTGACGGAGAGCAAAACAATTATC
TCCAATCCCTAGAAGTGCAAGTCATGCTAGACACTCTTCGTGTCATTCACAATCCCCTGCAAGACTACGCCTTGGTTGCC
CTTATGAAGTCTCCAATGTTTGGTTTTGATGAGGATGAGCTAGCACGTTTGTCCCTTCAGAAAGCAGAGGATAAAGTCCA
CGAAAATCTCTATGAGAAACTGGTCAATGCACAAAAAATGGCAAGTAGTCAAAAAGGTTTGATTCACACAGCTCTAGCTG
AAAAACTAAAGCAATTCATGGATATCCTAGCTTCTTGGCGCTTGTATGCCAAAACCCACTCTCTCTATGACTTGATTTGG
AAGATTTACAACGACCGTTTTTATTATGACTATGTTGGGGCTTTGCCGAATGGTCCTGCTAGGCAGGCCAATCTCTATGC
CCTAGCACTGCGTGCTGATCAATTTGAAAAGAGCAATTTCAAAGGTTTGTCGCGTTTTATTCGTATGATTGACCAAGTCT
TAGAAGCCCAGCACGATTTGGCAAGCGTGGCCGTCGCACCGCCAAAAGATGCAGTAGAGCTCATGACCATCCACAAGAGT
AAGGGGCTGGAGTTTCCTTACGTCTTTATCCTCAATATGGATCAAGATTTCAACAAGCAAGACTCTATGTCAGAAGTCAT
TCTCAGTCGTCAGAATGGTCTTGGTGTCAAATATATTGCCAAGATGGAGACAGGGGCAGTAGAAGACCACTATCCTAAAA
CCATCAAACTCTCCATTCCTAGCCTGACCTATAGGCAGAATGAAGAGGAATTACAGCTAGCAAGCTATTCTGAGCAGATG
CGTTTGCTGTATGTTGCTATGACGCGGGCTGAGAAAAAGCTCTATCTTGTCGGCAAGGGTTCTCGTGAAAAGCTGGAAGC
CAAGCAATACCCAGCAGCCAAAAATGGGAAACTAAATAGCAATACTAGACTGCAAGCACGGAATTTCCAAGATTGGCTTT
GGGCTATCAGTAAAGTGTTTACTAAGGACAAGCTCAACTTTAGTTATCGTTTTATTGGCGAAGATCAGTTGACCAGAGAA
GCTATCGGAGAGTTGGAAACCAAGAGTCCTCTCCAAGATAGCTCCCAAGCAGACAATCGTCAGTCAGATACCATCAAAGA
AGCTCTGAAAATGCTGAAGGAGGTGGAAGTTTATAATACTCTTCACCGCGCAGCTATTGAACTTCCTAGTGTTCAAACCC
CAAGTCAAATCAAGAAATTCTACGAACCAGTTATGGATATGGAAGGTGTCGAGATTGCTGGTCAAGGTCAGTCAGTAGGC
AAGAAAATCAGCTTCGATTTGCCAGATTTTTCAACAAAAGAAAAGGTAACTGGAGCTGAGATTGGTAGTGCTACTCACGA
ACTCATGCAGAGAATTGACCTCAGCCAGCAACTAACCCTTGCTAGCCTAACAGAAACACTCAAACAAGTTCAAACTAGCC
AAGCTGTCAGAGACAAGATCAATCTTGATAAAATTCTTGCTTTCTTTGACACAGTACTCGGTCAGGAAATTCTTGCTAAT
ACCGACCATCTCTATCGCGAGCAACCTTTCTCCATGCTCAAACGAGACCAAAAGAGTCAGGAAGACTTTGTTGTCCGTGG
TATCCTTGATGGCTATCTGCTTTACGAAAACAAAATTGTTCTGTTCGACTACAAGACAGACCGCTATGATGAACCAAGTC
AACTCGTAGACCGCTATCGTGGTCAGTTAGCTCTATACGAAGAGGCTTTATCACGAGCCTATTCGATTGAAAATATTGAA
AAATACTTGATTTTACTCGGTAAAGACGAGGCTCAAGTTGTAAAAGTATAA

Domains

Predicted by InterProScan.

• PD-(D/E)XK nuclease superfamily (PDDEXK_1) (1054-1193)

• UvrD-like helicase C-terminal domain (UvrD_C) (479-896)

• UvrD/REP helicase N-terminal domain (UvrD-helicase) (29-469)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
rexA	Streptococcus pneumoniae R6	98.766	100	0.988