Detailed information NTG0295906

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: CFC57_RS14150
• Genome accession: NZ_CP029751
• Coordinates: 2749798..2750685 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain Smith
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2744798..2755685

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CFC57_RS14120 (CFC57_14730)	-	2744801..2744892 (+)	92	Protein_2715	hypothetical protein	-
CFC57_RS14125 (CFC57_14735)	-	2745000..2745497 (-)	498	WP_001065267.1	glutathione peroxidase	-
CFC57_RS14130 (CFC57_14740)	-	2745507..2745767 (-)	261	WP_011382405.1	hypothetical protein	-
CFC57_RS14135 (CFC57_14750)	-	2746149..2746262 (-)	114	WP_072468803.1	hypothetical protein	-
CFC57_RS14140 (CFC57_14755)	-	2746938..2748938 (-)	2001	WP_000776729.1	ABC transporter permease	-
CFC57_RS14145 (CFC57_14760)	-	2748935..2749690 (-)	756	WP_000923770.1	ABC transporter ATP-binding protein	-
CFC57_RS14150 (CFC57_14765)	braS	2749798..2750685 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
CFC57_RS14155 (CFC57_14770)	braR	2750696..2751361 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
CFC57_RS14160 (CFC57_14775)	-	2751387..2751587 (-)	201	WP_000604725.1	hypothetical protein	-
CFC57_RS14165 (CFC57_14780)	-	2751785..2753209 (+)	1425	WP_000948998.1	alkaline phosphatase	-
CFC57_RS14945 (CFC57_14785)	-	2753269..2753370 (-)	102	WP_000731972.1	SE2200 family small protein	-
CFC57_RS14175 (CFC57_14790)	-	2753492..2753947 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
CFC57_RS14180 (CFC57_14795)	-	2754192..2754953 (-)	762	WP_000323445.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=295906 CFC57_RS14150 WP_000143420.1 2749798..2750685(-) (braS) [Staphylococcus aureus strain Smith]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=295906 CFC57_RS14150 WP_000143420.1 2749798..2750685(-) (braS) [Staphylococcus aureus strain Smith]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993