Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   CFC57_RS11130 Genome accession   NZ_CP029751
Coordinates   2149536..2150252 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain Smith     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2144536..2155252
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CFC57_RS11100 (CFC57_11550) - 2144783..2145409 (+) 627 WP_000522373.1 nitroreductase family protein -
  CFC57_RS11105 (CFC57_11555) - 2145738..2146523 (+) 786 WP_000867954.1 carbon-nitrogen family hydrolase -
  CFC57_RS14895 (CFC57_11560) - 2147123..2147257 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  CFC57_RS11115 (CFC57_11565) - 2147493..2148056 (+) 564 WP_001105711.1 accessory gene regulator AgrB -
  CFC57_RS11120 (CFC57_11570) agrD 2148060..2148200 (+) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  CFC57_RS11125 (CFC57_11575) agrC 2148225..2149517 (+) 1293 WP_000387815.1 quorum-sensing sensor histidine kinase AgrC -
  CFC57_RS11130 (CFC57_11580) agrA 2149536..2150252 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  CFC57_RS11135 (CFC57_11585) - 2150324..2150431 (+) 108 WP_001803734.1 hypothetical protein -
  CFC57_RS11140 (CFC57_11590) - 2150619..2151578 (-) 960 WP_001216203.1 carbohydrate kinase -
  CFC57_RS11145 (CFC57_11595) - 2151575..2153059 (-) 1485 WP_000141424.1 sucrose-6-phosphate hydrolase -
  CFC57_RS11150 (CFC57_11600) - 2153208..2154158 (-) 951 WP_000790321.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=295902 CFC57_RS11130 WP_000688492.1 2149536..2150252(+) (agrA) [Staphylococcus aureus strain Smith]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=295902 CFC57_RS11130 WP_000688492.1 2149536..2150252(+) (agrA) [Staphylococcus aureus strain Smith]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACGTTTGTCTACAAAGTTGCAGCGATGGACTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACACGTATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAACATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment