Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   EQH37_RS05555 Genome accession   NZ_CP035243
Coordinates   1113281..1113745 (-) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus pneumoniae strain TVO_1901946     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1108281..1118745
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH37_RS05535 (EQH37_05855) - 1109232..1110200 (-) 969 WP_000105360.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -
  EQH37_RS05540 (EQH37_05860) pdrM 1110354..1111715 (-) 1362 WP_000278537.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  EQH37_RS05545 (EQH37_05865) - 1111726..1111986 (-) 261 WP_001105925.1 hypothetical protein -
  EQH37_RS05550 (EQH37_05870) - 1112000..1113268 (-) 1269 WP_000924490.1 dihydroorotase -
  EQH37_RS05555 (EQH37_05875) mutX 1113281..1113745 (-) 465 WP_001135768.1 8-oxo-dGTP diphosphatase Machinery gene
  EQH37_RS05560 (EQH37_05880) - 1113755..1114408 (-) 654 WP_001809694.1 uracil-DNA glycosylase -
  EQH37_RS05565 (EQH37_05885) - 1114546..1115148 (-) 603 WP_054366177.1 hypothetical protein -
  EQH37_RS05570 (EQH37_05890) - 1115206..1115919 (-) 714 WP_000499429.1 YjjG family noncanonical pyrimidine nucleotidase -
  EQH37_RS05575 (EQH37_05895) - 1116481..1117827 (+) 1347 WP_088815832.1 IS1380-like element ISSpn5 family transposase -
  EQH37_RS05580 (EQH37_05900) dhaM 1118086..1118466 (-) 381 WP_000443785.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  EQH37_RS10965 - 1118466..1118540 (-) 75 Protein_1124 dihydroxyacetone kinase subunit L -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=295753 EQH37_RS05555 WP_001135768.1 1113281..1113745(-) (mutX) [Streptococcus pneumoniae strain TVO_1901946]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=295753 EQH37_RS05555 WP_001135768.1 1113281..1113745(-) (mutX) [Streptococcus pneumoniae strain TVO_1901946]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGCGCGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGACGCTAGAATGGGTTCC
CTATGATGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987