Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   EQH38_RS06280 Genome accession   NZ_CP035242
Coordinates   1194504..1194968 (+) Length   154 a.a.
NCBI ID   WP_001135768.1    Uniprot ID   A4L7L7
Organism   Streptococcus pneumoniae strain TVO_1901947     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1189504..1199968
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH38_RS10880 - 1189709..1189783 (+) 75 Protein_1208 dihydroxyacetone kinase subunit L -
  EQH38_RS06255 (EQH38_06605) dhaM 1189783..1190163 (+) 381 WP_000443785.1 dihydroxyacetone kinase phosphoryl donor subunit DhaM -
  EQH38_RS06260 (EQH38_06610) - 1190422..1191768 (-) 1347 WP_061815350.1 IS1380-like element ISSpn5 family transposase -
  EQH38_RS06265 (EQH38_06615) - 1192330..1193043 (+) 714 WP_000499429.1 YjjG family noncanonical pyrimidine nucleotidase -
  EQH38_RS06270 (EQH38_06620) - 1193101..1193703 (+) 603 WP_054366177.1 hypothetical protein -
  EQH38_RS06275 (EQH38_06625) - 1193841..1194494 (+) 654 WP_001809694.1 uracil-DNA glycosylase -
  EQH38_RS06280 (EQH38_06630) mutX 1194504..1194968 (+) 465 WP_001135768.1 8-oxo-dGTP diphosphatase Machinery gene
  EQH38_RS06285 (EQH38_06635) - 1194981..1196249 (+) 1269 WP_000924490.1 dihydroorotase -
  EQH38_RS06290 (EQH38_06640) - 1196263..1196523 (+) 261 WP_001105925.1 hypothetical protein -
  EQH38_RS06295 (EQH38_06645) pdrM 1196534..1197895 (+) 1362 WP_000278537.1 sodium-coupled multidrug efflux MATE transporter PdrM -
  EQH38_RS06300 (EQH38_06650) - 1198049..1199017 (+) 969 WP_000105360.1 thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 17812.16 Da        Isoelectric Point: 4.2287

>NTDB_id=295653 EQH38_RS06280 WP_001135768.1 1194504..1194968(+) (mutX) [Streptococcus pneumoniae strain TVO_1901947]
MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGETPQECAAREILEETGLKAKPVLKGVITFPEFTPDLD
WYTYVFKVTEFEGDLIDCNEGTLEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE

Nucleotide


Download         Length: 465 bp        

>NTDB_id=295653 EQH38_RS06280 WP_001135768.1 1194504..1194968(+) (mutX) [Streptococcus pneumoniae strain TVO_1901947]
ATGCCTCAGTTAGCGACGATTTGCTACATTGATAATGGGAAAGAACTGCTCATGCTCCATCGTAATAAGAAACCCAATGA
TGTCCATGAAGGGAAATGGATTGGTGTGGGTGGTAAGCTAGAGAGAGGAGAGACGCCCCAGGAATGCGCGGCGCGTGAAA
TCCTTGAAGAAACAGGGCTCAAAGCCAAGCCAGTTCTAAAAGGTGTCATCACTTTTCCTGAATTTACACCAGATTTAGAC
TGGTACACCTATGTTTTTAAGGTGACGGAGTTTGAGGGCGACTTGATTGACTGCAATGAGGGGACGCTAGAATGGGTTCC
CTATGATGAGGTTTTGAGCAAGCCGACTTGGGAAGGTGACCACACCTTTGTTGAGTGGCTTTTAGAGGATAAACCCTTCT
TTTCAGCCAAGTTTGTTTATGATGGGGATAAATTGTTGGATACCCAAGTTGATTTCTATGAATAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-127)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A4L7L7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

98.701

100

0.987