Detailed information NTG0029551

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: USA300HOU_RS14260
• Genome accession: NC_010079
• Coordinates: 2769215..2770102 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus subsp. aureus USA300_TCH1516
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2764215..2775102

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
USA300HOU_RS14225	-	2764234..2764326 (+)	93	WP_010956583.1	hypothetical protein	-
USA300HOU_RS14230 (USA300HOU_2619)	-	2764434..2764931 (-)	498	WP_001065268.1	glutathione peroxidase	-
USA300HOU_RS14235	-	2764941..2765201 (-)	261	WP_001789910.1	hypothetical protein	-
USA300HOU_RS14240	-	2765583..2765696 (-)	114	WP_001791776.1	hypothetical protein	-
USA300HOU_RS14250 (USA300HOU_2621)	-	2766355..2768355 (-)	2001	WP_000776751.1	ABC transporter permease	-
USA300HOU_RS14255 (USA300HOU_2622)	-	2768352..2769107 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
USA300HOU_RS14260 (USA300HOU_2623)	braS	2769215..2770102 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
USA300HOU_RS14265 (USA300HOU_2624)	braR	2770113..2770778 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
USA300HOU_RS14270 (USA300HOU_2625)	-	2770804..2771004 (-)	201	WP_000604728.1	hypothetical protein	-
USA300HOU_RS14280 (USA300HOU_2626)	-	2771202..2772626 (+)	1425	WP_000953744.1	alkaline phosphatase	-
USA300HOU_RS15930	-	2772696..2772806 (+)	111	WP_001791296.1	hypothetical protein	-
USA300HOU_RS14285 (USA300HOU_2628)	-	2772909..2773364 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
USA300HOU_RS14290 (USA300HOU_2629)	-	2773609..2774370 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=29551 USA300HOU_RS14260 WP_000143419.1 2769215..2770102(-) (braS) [Staphylococcus aureus subsp. aureus USA300_TCH1516]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=29551 USA300HOU_RS14260 WP_000143419.1 2769215..2770102(-) (braS) [Staphylococcus aureus subsp. aureus USA300_TCH1516]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997