Detailed information NTG0295024

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: CSB76_RS10310
• Genome accession: NZ_CP029673
• Coordinates: 1991677..1992720 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain AR_0220
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1986677..1997720

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CSB76_RS10280 (CSB76_1884)	-	1987098..1988354 (-)	1257	WP_001795108.1	aminopeptidase	-
CSB76_RS10285 (CSB76_1885)	-	1988357..1988557 (-)	201	WP_000180460.1	DUF1128 family protein	-
CSB76_RS10290 (CSB76_1886)	-	1988704..1989168 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
CSB76_RS10295 (CSB76_1887)	-	1989175..1989450 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
CSB76_RS10300 (CSB76_1888)	-	1989728..1990945 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
CSB76_RS10305 (CSB76_1889)	vraR	1991058..1991687 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
CSB76_RS10310 (CSB76_1890)	vraS	1991677..1992720 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
CSB76_RS10315 (CSB76_1891)	liaF	1992717..1993418 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
CSB76_RS10320 (CSB76_1892)	-	1993433..1993819 (-)	387	WP_001110179.1	hypothetical protein	-
CSB76_RS10325 (CSB76_1893)	map	1994036..1994794 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
CSB76_RS10335 (CSB76_1894)	-	1995325..1996311 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
CSB76_RS10345 (CSB76_1895)	-	1996742..1997155 (-)	414	WP_001557448.1	hypothetical protein	-
CSB76_RS10350	-	1997184..1997294 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=295024 CSB76_RS10310 WP_001017131.1 1991677..1992720(-) (vraS) [Staphylococcus aureus strain AR_0220]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=295024 CSB76_RS10310 WP_001017131.1 1991677..1992720(-) (vraS) [Staphylococcus aureus strain AR_0220]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1