Detailed information NTG0294865

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: CSB81_RS00340
• Genome accession: NZ_CP029667
• Coordinates: 42664..43551 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain AR_0225
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 37664..48551

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CSB81_RS00310 (CSB81_0027)	-	38396..39157 (+)	762	WP_000323455.1	alpha/beta hydrolase family protein	-
CSB81_RS00315 (CSB81_0028)	-	39402..39857 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
CSB81_RS15700	-	39979..40080 (+)	102	WP_000731972.1	SE2200 family small protein	-
CSB81_RS00325 (CSB81_0029)	-	40140..41564 (-)	1425	WP_000953744.1	alkaline phosphatase	-
CSB81_RS00330 (CSB81_0030)	-	41762..41962 (+)	201	WP_000604728.1	hypothetical protein	-
CSB81_RS00335 (CSB81_0031)	braR	41988..42653 (+)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
CSB81_RS00340 (CSB81_0032)	braS	42664..43551 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
CSB81_RS00345 (CSB81_0033)	-	43659..44414 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
CSB81_RS00350 (CSB81_0034)	-	44411..46411 (+)	2001	WP_000776751.1	ABC transporter permease	-
CSB81_RS00355	-	47070..47183 (+)	114	WP_001791776.1	hypothetical protein	-
CSB81_RS00365	-	47565..47825 (+)	261	WP_001789910.1	hypothetical protein	-
CSB81_RS00370 (CSB81_0036)	-	47835..48332 (+)	498	WP_001065268.1	glutathione peroxidase	-
CSB81_RS00375	-	48440..48532 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=294865 CSB81_RS00340 WP_000143419.1 42664..43551(+) (braS) [Staphylococcus aureus strain AR_0225]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=294865 CSB81_RS00340 WP_000143419.1 42664..43551(+) (braS) [Staphylococcus aureus strain AR_0225]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997