Detailed information NTG0294826

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: CSB82_RS03730
• Genome accession: NZ_CP029664
• Coordinates: 670281..671324 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain AR_0226
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 665281..676324

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CSB82_RS03685	-	665651..665761 (+)	111	WP_001790257.1	hypothetical protein	-
CSB82_RS03690 (CSB82_0662)	-	665790..666203 (+)	414	WP_001549145.1	hypothetical protein	-
CSB82_RS03700 (CSB82_0663)	-	666693..667679 (-)	987	WP_000999713.1	aromatic acid exporter family protein	-
CSB82_RS03715 (CSB82_0664)	map	668207..668965 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
CSB82_RS03720 (CSB82_0665)	-	669182..669568 (+)	387	WP_001110179.1	hypothetical protein	-
CSB82_RS03725 (CSB82_0666)	liaF	669583..670284 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
CSB82_RS03730 (CSB82_0667)	vraS	670281..671324 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
CSB82_RS03735 (CSB82_0668)	vraR	671314..671943 (+)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
CSB82_RS03740 (CSB82_0669)	-	672059..673276 (-)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
CSB82_RS03745 (CSB82_0670)	-	673554..673829 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
CSB82_RS03750 (CSB82_0671)	-	673836..674300 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
CSB82_RS03755 (CSB82_0672)	-	674447..674647 (+)	201	WP_000180461.1	DUF1128 family protein	-
CSB82_RS03760 (CSB82_0673)	-	674650..675906 (+)	1257	WP_110418048.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=294826 CSB82_RS03730 WP_001017131.1 670281..671324(+) (vraS) [Staphylococcus aureus strain AR_0226]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=294826 CSB82_RS03730 WP_001017131.1 670281..671324(+) (vraS) [Staphylococcus aureus strain AR_0226]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1