Detailed information    

insolico Bioinformatically predicted

Overview

Name   brsR   Type   Regulator
Locus tag   EQH46_RS00825 Genome accession   NZ_CP035234
Coordinates   161484..161924 (-) Length   146 a.a.
NCBI ID   WP_000861956.1    Uniprot ID   A0A0H2UNA2
Organism   Streptococcus pneumoniae strain TVO_1902277     
Function   antagonizing the proteolysis of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 156484..166924
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH46_RS00800 (EQH46_00855) - 156736..158022 (+) 1287 WP_000278891.1 response regulator transcription factor -
  EQH46_RS00805 (EQH46_00860) - 158083..158616 (+) 534 WP_000729034.1 hypothetical protein -
  EQH46_RS00810 (EQH46_00865) nrdI 158694..159164 (+) 471 WP_000849621.1 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI -
  EQH46_RS00815 (EQH46_00875) - 159457..160719 (-) 1263 WP_238134132.1 NRAMP family divalent metal transporter -
  EQH46_RS00820 (EQH46_00880) - 161029..161487 (-) 459 WP_000745059.1 DUF3021 domain-containing protein -
  EQH46_RS00825 (EQH46_00885) brsR 161484..161924 (-) 441 WP_000861956.1 LytTR family DNA-binding domain-containing protein Regulator
  EQH46_RS00830 (EQH46_00895) - 162357..163223 (+) 867 WP_000537009.1 helix-turn-helix domain-containing protein -
  EQH46_RS10830 - 163377..163505 (+) 129 WP_001257108.1 hypothetical protein -
  EQH46_RS00835 (EQH46_00900) - 163561..164118 (+) 558 WP_000358739.1 phosphopantothenate--cysteine ligase family flavoprotein -
  EQH46_RS00840 (EQH46_00905) - 164339..165445 (+) 1107 WP_000608719.1 pyridoxal-dependent decarboxylase -
  EQH46_RS00845 (EQH46_00910) - 165421..166812 (+) 1392 WP_000358548.1 hypothetical protein -

Sequence

Protein


Download         Length: 146 a.a.        Molecular weight: 17183.84 Da        Isoelectric Point: 5.3783

>NTDB_id=294767 EQH46_RS00825 WP_000861956.1 161484..161924(-) (brsR) [Streptococcus pneumoniae strain TVO_1902277]
MKVELQISETYEEEKLIVQAPQETEKVQKVIEFAENLDQREKIKGKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSI
DLRLYQVLKLLPTNFIQISQSEIINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL

Nucleotide


Download         Length: 441 bp        

>NTDB_id=294767 EQH46_RS00825 WP_000861956.1 161484..161924(-) (brsR) [Streptococcus pneumoniae strain TVO_1902277]
ATGAAAGTAGAACTACAGATTAGTGAGACTTACGAGGAGGAAAAGCTGATTGTCCAAGCACCTCAAGAAACCGAAAAAGT
CCAGAAAGTCATCGAGTTCGCAGAAAATCTGGACCAAAGAGAAAAAATCAAAGGAAAAATCGATGATCAGGTCTATCTAG
TTGAGATTGGCAAGATTCAGCGCTTCTATATCGAGAATCGGAAGGTTCTAGCAGAAACCGCGAGTCAGACCTACAGCATT
GATTTGCGACTCTATCAGGTTCTTAAACTCTTGCCAACCAATTTTATCCAAATTTCCCAATCAGAAATCATCAATATCGA
TTCCATCTCTCACCTCAAGCTCACGCCAAACGGTCTGGTAGAAATTTTCTTGAAAAACGAAAGCTTCACCTACTCTTCAC
GCCGTTATCTAAAAACCATCAAGGAGAAATTAGAACTATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(50-144)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UNA2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  brsR Streptococcus mutans UA159

36.054

100

0.363