Detailed information NTG0294711

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: CSC52_RS05495
• Genome accession: NZ_CP029658
• Coordinates: 1016953..1017996 (+)
• Length: 347 a.a.
• NCBI ID: WP_110184172.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain AR_0467
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1011953..1022996

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CSC52_RS05455	-	1012379..1012489 (+)	111	WP_001790257.1	hypothetical protein	-
CSC52_RS05460 (CSC52_1018)	-	1012518..1012931 (+)	414	WP_001557448.1	hypothetical protein	-
CSC52_RS05470 (CSC52_1019)	-	1013362..1014348 (-)	987	WP_000999717.1	aromatic acid exporter family protein	-
CSC52_RS05480 (CSC52_1020)	map	1014879..1015637 (+)	759	WP_000636142.1	type I methionyl aminopeptidase	-
CSC52_RS05485 (CSC52_1021)	-	1015854..1016240 (+)	387	WP_001110179.1	hypothetical protein	-
CSC52_RS05490 (CSC52_1022)	liaF	1016255..1016956 (+)	702	WP_110184171.1	cell wall-active antibiotics response protein LiaF	-
CSC52_RS05495 (CSC52_1023)	vraS	1016953..1017996 (+)	1044	WP_110184172.1	sensor histidine kinase	Regulator
CSC52_RS05500 (CSC52_1024)	vraR	1017986..1018615 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
CSC52_RS05505 (CSC52_1025)	-	1018728..1019945 (-)	1218	WP_110184173.1	YihY/virulence factor BrkB family protein	-
CSC52_RS05510 (CSC52_1026)	-	1020223..1020498 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
CSC52_RS05515 (CSC52_1027)	-	1020505..1020969 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
CSC52_RS05520 (CSC52_1028)	-	1021116..1021316 (+)	201	WP_000180460.1	DUF1128 family protein	-
CSC52_RS05525 (CSC52_1029)	-	1021319..1022575 (+)	1257	WP_001795108.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40038.56 Da
• Isoelectric Point: 6.0577

>NTDB_id=294711 CSC52_RS05495 WP_110184172.1 1016953..1017996(+) (vraS) [Staphylococcus aureus strain AR_0467]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLILNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERVLEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=294711 CSC52_RS05495 WP_110184172.1 1016953..1017996(+) (vraS) [Staphylococcus aureus strain AR_0467]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTAATTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGTTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	99.424	100	0.994