Detailed information NTG0294692

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: CSC53_RS10665
• Genome accession: NZ_CP029657
• Coordinates: 2031530..2032573 (-)
• Length: 347 a.a.
• NCBI ID: WP_108720648.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain AR_0468
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2026530..2037573

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CSC53_RS10635 (CSC53_1938)	-	2026951..2028207 (-)	1257	WP_001795108.1	aminopeptidase	-
CSC53_RS10640 (CSC53_1939)	-	2028210..2028410 (-)	201	WP_000180460.1	DUF1128 family protein	-
CSC53_RS10645 (CSC53_1940)	-	2028557..2029021 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
CSC53_RS10650 (CSC53_1941)	-	2029028..2029303 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
CSC53_RS10655 (CSC53_1942)	-	2029581..2030798 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
CSC53_RS10660 (CSC53_1943)	vraR	2030911..2031540 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
CSC53_RS10665 (CSC53_1944)	vraS	2031530..2032573 (-)	1044	WP_108720648.1	sensor histidine kinase	Regulator
CSC53_RS10670 (CSC53_1945)	liaF	2032570..2033271 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
CSC53_RS10675 (CSC53_1946)	-	2033286..2033672 (-)	387	WP_001110179.1	hypothetical protein	-
CSC53_RS10680 (CSC53_1947)	map	2033889..2034647 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
CSC53_RS10690 (CSC53_1948)	-	2035178..2036164 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
CSC53_RS10700 (CSC53_1949)	-	2036595..2037008 (-)	414	WP_001557448.1	hypothetical protein	-
CSC53_RS10705	-	2037037..2037147 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40072.57 Da
• Isoelectric Point: 6.0577

>NTDB_id=294692 CSC53_RS10665 WP_108720648.1 2031530..2032573(-) (vraS) [Staphylococcus aureus strain AR_0468]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERVLEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=294692 CSC53_RS10665 WP_108720648.1 2031530..2032573(-) (vraS) [Staphylococcus aureus strain AR_0468]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGTTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	99.712	100	0.997