Detailed information NTG0294669

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: CSC53_RS05330
• Genome accession: NZ_CP029657
• Coordinates: 1011017..1012003 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain AR_0468
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1006017..1017003

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CSC53_RS05305 (CSC53_0952)	opp4B	1006231..1007193 (+)	963	WP_000915997.1	oligopeptide ABC transporter permease	-
CSC53_RS05310 (CSC53_0953)	opp4C	1007205..1008086 (+)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
CSC53_RS05315 (CSC53_0954)	trpS	1008128..1009117 (-)	990	WP_000448934.1	tryptophan--tRNA ligase	-
CSC53_RS05320 (CSC53_0955)	spxA	1009411..1009806 (+)	396	WP_000258003.1	transcriptional regulator SpxA	-
CSC53_RS05325 (CSC53_0956)	mecA	1010177..1010896 (+)	720	WP_001217728.1	adaptor protein MecA	-
CSC53_RS05330 (CSC53_0957)	coiA	1011017..1012003 (+)	987	WP_000959282.1	competence protein CoiA family protein	Machinery gene
CSC53_RS05335 (CSC53_0958)	pepF	1012051..1013859 (+)	1809	WP_000082725.1	oligoendopeptidase F	-
CSC53_RS05340 (CSC53_0959)	yjbH	1014319..1015125 (-)	807	WP_000896697.1	protease adaptor protein YjbH	-
CSC53_RS05345 (CSC53_0960)	-	1015148..1015513 (-)	366	WP_000214070.1	truncated hemoglobin YjbI	-
CSC53_RS05350 (CSC53_0961)	-	1015617..1016210 (-)	594	WP_000224619.1	CYTH domain-containing protein	-
CSC53_RS05355 (CSC53_0962)	-	1016396..1016743 (+)	348	WP_001242103.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=294669 CSC53_RS05330 WP_000959282.1 1011017..1012003(+) (coiA) [Staphylococcus aureus strain AR_0468]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=294669 CSC53_RS05330 WP_000959282.1 1011017..1012003(+) (coiA) [Staphylococcus aureus strain AR_0468]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976