Detailed information NTG0294620

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: CSC54_RS03570
• Genome accession: NZ_CP029655
• Coordinates: 703901..704788 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain AR_0469
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 698901..709788

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CSC54_RS03540 (CSC54_0628)	-	699633..700394 (+)	762	WP_000323441.1	alpha/beta hydrolase family protein	-
CSC54_RS03545 (CSC54_0629)	-	700639..701094 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
CSC54_RS15240	-	701216..701317 (+)	102	WP_000731976.1	SE2200 family small protein	-
CSC54_RS03555 (CSC54_0630)	-	701377..702801 (-)	1425	WP_000953755.1	alkaline phosphatase	-
CSC54_RS03560 (CSC54_0631)	-	702999..703199 (+)	201	WP_000604730.1	hypothetical protein	-
CSC54_RS03565 (CSC54_0632)	braR	703225..703890 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
CSC54_RS03570 (CSC54_0633)	braS	703901..704788 (+)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
CSC54_RS03575 (CSC54_0634)	-	704896..705651 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
CSC54_RS03580 (CSC54_0635)	-	705648..707648 (+)	2001	WP_000776750.1	ABC transporter permease	-
CSC54_RS03585	-	708307..708420 (+)	114	Protein_629	hypothetical protein	-
CSC54_RS03595	-	708802..709062 (+)	261	WP_001791974.1	hypothetical protein	-
CSC54_RS03600 (CSC54_0637)	-	709072..709569 (+)	498	WP_001065268.1	glutathione peroxidase	-
CSC54_RS03605	-	709677..709769 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=294620 CSC54_RS03570 WP_000143425.1 703901..704788(+) (braS) [Staphylococcus aureus strain AR_0469]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=294620 CSC54_RS03570 WP_000143425.1 703901..704788(+) (braS) [Staphylococcus aureus strain AR_0469]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1