Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | CSC54_RS02590 | Genome accession | NZ_CP029655 |
| Coordinates | 498734..500083 (+) | Length | 449 a.a. |
| NCBI ID | WP_000815646.1 | Uniprot ID | Q9XB96 |
| Organism | Staphylococcus aureus strain AR_0469 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 498734..550798 | 498734..500083 | within | 0 |
Gene organization within MGE regions
Location: 498734..550798
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| CSC54_RS02590 (CSC54_0451) | ccrA | 498734..500083 (+) | 1350 | WP_000815646.1 | recombinase family protein | Machinery gene |
| CSC54_RS02595 (CSC54_0452) | ccrB | 500105..501733 (+) | 1629 | WP_001186602.1 | recombinase family protein | Machinery gene |
| CSC54_RS02600 (CSC54_0453) | - | 502251..502601 (+) | 351 | WP_000859155.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| CSC54_RS02605 (CSC54_0454) | - | 502688..502999 (+) | 312 | WP_000700853.1 | DUF960 family protein | - |
| CSC54_RS02610 (CSC54_0455) | - | 503017..503523 (+) | 507 | WP_001092169.1 | DUF1643 domain-containing protein | - |
| CSC54_RS02615 (CSC54_0456) | - | 503544..503861 (+) | 318 | WP_000659050.1 | JAB domain-containing protein | - |
| CSC54_RS02620 (CSC54_0457) | - | 503980..505065 (+) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| CSC54_RS02625 (CSC54_0458) | - | 505062..506954 (+) | 1893 | WP_001557544.1 | site-specific integrase | - |
| CSC54_RS02630 (CSC54_0459) | - | 506961..507338 (+) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| CSC54_RS02635 (CSC54_0460) | - | 507489..508271 (+) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| CSC54_RS02640 (CSC54_0461) | erm(A) | 508397..509128 (-) | 732 | WP_001072201.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| CSC54_RS02650 (CSC54_0462) | - | 509521..510183 (+) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| CSC54_RS02660 | - | 510528..511166 (-) | 639 | Protein_459 | sulfite exporter TauE/SafE family protein | - |
| CSC54_RS02665 (CSC54_0464) | cstR | 511166..511426 (-) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| CSC54_RS02670 (CSC54_0465) | - | 511562..512626 (+) | 1065 | WP_110231660.1 | DsrE/DsrF/DrsH-like family protein | - |
| CSC54_RS02675 (CSC54_0466) | cstB | 512659..513993 (+) | 1335 | Protein_462 | persulfide dioxygenase-sulfurtransferase CstB | - |
| CSC54_RS02685 (CSC54_0468) | - | 514107..515216 (-) | 1110 | WP_000943131.1 | ROK family transcriptional regulator | - |
| CSC54_RS02690 | psm-mec | 515571..515639 (+) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| CSC54_RS02695 (CSC54_0469) | mecI | 515724..516095 (-) | 372 | WP_000369214.1 | mecA-type methicillin resistance repressor MecI | - |
| CSC54_RS02700 (CSC54_0470) | mecR1 | 516095..517852 (-) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| CSC54_RS02705 (CSC54_0471) | mecA | 517949..519958 (+) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| CSC54_RS02710 (CSC54_0472) | - | 520004..520432 (-) | 429 | WP_000872606.1 | MaoC family dehydratase | - |
| CSC54_RS02715 (CSC54_0473) | - | 520529..521272 (-) | 744 | WP_000958858.1 | glycerophosphoryl diester phosphodiesterase | - |
| CSC54_RS02720 (CSC54_0474) | - | 521537..522211 (+) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| CSC54_RS02725 (CSC54_0475) | aadD1 | 522404..523174 (+) | 771 | WP_001795128.1 | aminoglycoside O-nucleotidyltransferase ANT(4')-Ia | - |
| CSC54_RS02730 (CSC54_0476) | bleO | 523391..523795 (+) | 405 | WP_001242578.1 | bleomycin binding protein | - |
| CSC54_RS02735 (CSC54_0477) | mobV | 524302..525564 (+) | 1263 | WP_000119405.1 | MobV family relaxase | - |
| CSC54_RS02740 | - | 525809..526792 (+) | 984 | Protein_474 | protein rep | - |
| CSC54_RS02750 (CSC54_0480) | - | 526883..527557 (+) | 675 | WP_001106057.1 | IS6-like element IS257 family transposase | - |
| CSC54_RS02755 (CSC54_0481) | - | 527589..527828 (-) | 240 | WP_001282728.1 | hypothetical protein | - |
| CSC54_RS02760 (CSC54_0482) | - | 528243..529499 (-) | 1257 | WP_000566670.1 | DUF3578 domain-containing protein | - |
| CSC54_RS02765 | - | 530031..530705 (-) | 675 | Protein_478 | IS6 family transposase | - |
| CSC54_RS02770 (CSC54_0485) | - | 530778..531047 (+) | 270 | WP_049370426.1 | hypothetical protein | - |
| CSC54_RS02775 (CSC54_0486) | - | 531929..532360 (+) | 432 | WP_000475804.1 | universal stress protein | - |
| CSC54_RS15135 | - | 532631..533313 (-) | 683 | Protein_481 | type I restriction enzyme endonuclease domain-containing protein | - |
| CSC54_RS02795 (CSC54_0488) | - | 533886..534332 (+) | 447 | WP_000711815.1 | ArgR family transcriptional regulator | - |
| CSC54_RS02800 (CSC54_0489) | arcA | 534601..535836 (+) | 1236 | WP_000249804.1 | arginine deiminase | - |
| CSC54_RS02805 (CSC54_0490) | arcD | 535922..537343 (+) | 1422 | WP_000344142.1 | arginine-ornithine antiporter | - |
| CSC54_RS02810 (CSC54_0491) | - | 537385..538074 (+) | 690 | WP_000272781.1 | Crp/Fnr family transcriptional regulator | - |
| CSC54_RS02815 (CSC54_0492) | argF | 538112..539110 (+) | 999 | WP_000793596.1 | ornithine carbamoyltransferase | - |
| CSC54_RS02820 (CSC54_0493) | arcC | 539130..540059 (+) | 930 | WP_000036756.1 | carbamate kinase | - |
| CSC54_RS02825 (CSC54_0494) | - | 540159..541010 (-) | 852 | WP_000832687.1 | IS3 family transposase | - |
| CSC54_RS02830 (CSC54_0495) | - | 541409..541651 (-) | 243 | WP_000931963.1 | hypothetical protein | - |
| CSC54_RS02835 (CSC54_0496) | - | 541666..542295 (-) | 630 | WP_001053439.1 | hypothetical protein | - |
| CSC54_RS02840 (CSC54_0497) | - | 543390..545315 (-) | 1926 | WP_002485723.1 | heavy metal translocating P-type ATPase | - |
| CSC54_RS02850 (CSC54_0498) | - | 545645..545971 (-) | 327 | WP_000391495.1 | metalloregulator ArsR/SmtB family transcription factor | - |
| CSC54_RS02855 (CSC54_0499) | - | 546178..546537 (+) | 360 | WP_001631039.1 | hypothetical protein | - |
| CSC54_RS02860 (CSC54_0500) | - | 546649..546987 (-) | 339 | Protein_494 | recombinase family protein | - |
| CSC54_RS02865 (CSC54_0501) | - | 546996..547625 (+) | 630 | Protein_495 | hypothetical protein | - |
| CSC54_RS02870 (CSC54_0502) | ccrA | 547812..549173 (+) | 1362 | WP_001631036.1 | recombinase family protein | Machinery gene |
| CSC54_RS02875 (CSC54_0503) | ccrB | 549170..550798 (+) | 1629 | WP_001631035.1 | recombinase family protein | Machinery gene |
Sequence
Protein
Download Length: 449 a.a. Molecular weight: 52607.20 Da Isoelectric Point: 9.9585
>NTDB_id=294613 CSC54_RS02590 WP_000815646.1 498734..500083(+) (ccrA) [Staphylococcus aureus strain AR_0469]
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRFKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYEYH
NGAFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRSQKQIKQTSSDNQLKQKIKCPCCNTTLTNMTVRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CKDFYQNQRIYTKIKGAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHTIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQTMQSSIA
MKQVIGYLRQSTMKQQSLAAQKQAIEAIAEKHHIQHINFYSDKQSGRKDNRSGYRQMTQLIQQGQCDILCCYRLNRLHRN
LKNALKLIKLCQTYHVHILSVHDGYFDMDQAFDRFKLNIFISLAELESDNIGEQVRNGLQEKAKQGRLITTHAPFGYEYH
NGAFIINQNESPTVKAVFNYYIKGHGYKKIAQLLEEDNTYINRQPYQVRNIIINPNYCGRVNNQYGQFDNMFPSIVSTSI
YEQAQRLRSQKQIKQTSSDNQLKQKIKCPCCNTTLTNMTVRKKNHTLRYYVCPKNMNASRFVCDFKGINAQTLEDKVLEV
CKDFYQNQRIYTKIKGAIDKRIKRQRNIEKHHTLTQEQLIEKLAQGIIDAETFREQTQSLRQQPQRTTSINGHQIQHTIQ
NIIQKRFTLNILYPYIETIHITKDKNLIGIYFKNEPLNIVNQTMQSSIA
Nucleotide
Download Length: 1350 bp
>NTDB_id=294613 CSC54_RS02590 WP_000815646.1 498734..500083(+) (ccrA) [Staphylococcus aureus strain AR_0469]
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAGGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACGCAATTAATTCAACAAGGGCAATGTGACATATTATGTTGTTATCGTCTTAATAGATTACATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACATACCATGTTCATATCTTAAGCGTACACGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGATTCAAGCTTAATATTTTTATCAGCTTGGCCGAACTTGAATCAGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACCCATGCGCCCTTTGGTTACGAATATCAC
AACGGAGCATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATCGCAAAAACAAATCAAACAGACATCTTCGGATAACCAACTAAAACAAAAAATCAA
ATGCCCATGTTGTAATACAACACTTACGAATATGACCGTTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCTCGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCAAAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAGGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATCGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCGCAACGCACTACATCTATCAATGGACATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAACCATGCAATCATCGATTGCATAA
ATGAAACAAGTCATAGGCTATTTACGTCAAAGTACGATGAAACAACAATCTCTTGCAGCACAGAAACAGGCTATCGAAGC
AATAGCCGAAAAACATCATATTCAACATATCAACTTTTATAGCGACAAACAATCAGGACGCAAAGATAATCGTAGTGGGT
ATCGACAAATGACGCAATTAATTCAACAAGGGCAATGTGACATATTATGTTGTTATCGTCTTAATAGATTACATCGTAAT
CTGAAAAATGCATTAAAACTCATCAAATTATGTCAAACATACCATGTTCATATCTTAAGCGTACACGATGGTTACTTTGA
TATGGATCAAGCTTTCGACCGATTCAAGCTTAATATTTTTATCAGCTTGGCCGAACTTGAATCAGATAACATTGGAGAAC
AAGTCAGAAATGGGCTTCAAGAAAAAGCAAAGCAAGGTCGATTGATTACAACCCATGCGCCCTTTGGTTACGAATATCAC
AACGGAGCATTCATCATCAATCAAAATGAGTCACCAACGGTAAAGGCTGTATTCAATTATTACATTAAAGGTCATGGTTA
TAAGAAAATTGCACAGTTATTAGAAGAAGATAACACGTATATCAATCGACAACCCTATCAAGTTCGTAACATTATCATCA
ATCCTAATTATTGTGGTCGTGTCAACAATCAATATGGCCAATTCGACAATATGTTTCCTTCTATTGTTTCCACAAGTATA
TATGAGCAAGCGCAGAGACTTCGATCGCAAAAACAAATCAAACAGACATCTTCGGATAACCAACTAAAACAAAAAATCAA
ATGCCCATGTTGTAATACAACACTTACGAATATGACCGTTAGAAAAAAGAATCATACATTACGTTACTACGTCTGTCCTA
AAAACATGAATGCTTCTCGCTTTGTCTGTGATTTTAAAGGCATCAATGCACAAACACTTGAAGATAAAGTATTAGAAGTG
TGCAAAGACTTTTATCAAAATCAACGCATCTACACAAAAATTAAAGGTGCGATTGACAAACGCATCAAAAGACAAAGAAA
CATAGAAAAACATCACACATTGACTCAAGAACAACTGATAGAAAAGTTGGCACAAGGCATCATCGATGCAGAAACGTTCA
GAGAACAAACGCAATCATTACGTCAACAACCGCAACGCACTACATCTATCAATGGACATCAAATACAACACACCATTCAA
AATATTATTCAAAAACGTTTCACGTTAAACATATTGTACCCCTATATTGAAACCATTCACATTACGAAAGATAAAAATCT
TATAGGAATCTATTTCAAAAATGAACCACTCAATATCGTCAATCAAACCATGCAATCATCGATTGCATAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus N315 |
100 |
100 |
1 |
| ccrA | Staphylococcus aureus COL |
74.833 |
100 |
0.748 |