Detailed information NTG0294603

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: CSC55_RS10740
• Genome accession: NZ_CP029653
• Coordinates: 2114133..2115176 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain AR_0470
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2109133..2120176

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CSC55_RS10710 (CSC55_1388)	-	2109554..2110810 (-)	1257	WP_001793983.1	aminopeptidase	-
CSC55_RS10715 (CSC55_1389)	-	2110813..2111013 (-)	201	WP_000180460.1	DUF1128 family protein	-
CSC55_RS10720 (CSC55_1390)	-	2111160..2111624 (+)	465	WP_000228670.1	low molecular weight protein-tyrosine-phosphatase	-
CSC55_RS10725 (CSC55_1391)	-	2111631..2111906 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
CSC55_RS10730 (CSC55_1392)	-	2112184..2113401 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
CSC55_RS10735 (CSC55_1393)	vraR	2113514..2114143 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
CSC55_RS10740 (CSC55_1394)	vraS	2114133..2115176 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
CSC55_RS10745 (CSC55_1395)	liaF	2115173..2115874 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
CSC55_RS10750 (CSC55_1396)	-	2115889..2116275 (-)	387	WP_001110178.1	hypothetical protein	-
CSC55_RS10755 (CSC55_1397)	map	2116492..2117250 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
CSC55_RS10765 (CSC55_1398)	-	2117950..2118936 (+)	987	WP_001014423.1	aromatic acid exporter family protein	-
CSC55_RS10770 (CSC55_1399)	-	2119125..2119538 (-)	414	WP_001573815.1	hypothetical protein	-
CSC55_RS10775	-	2119567..2119677 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=294603 CSC55_RS10740 WP_001017131.1 2114133..2115176(-) (vraS) [Staphylococcus aureus strain AR_0470]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=294603 CSC55_RS10740 WP_001017131.1 2114133..2115176(-) (vraS) [Staphylococcus aureus strain AR_0470]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGACTT
ATACCATACACTTGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1