Detailed information NTG0294559

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: CSC56_RS13160
• Genome accession: NZ_CP029652
• Coordinates: 2521601..2522644 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain AR_0471
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2516601..2527644

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CSC56_RS13125	-	2517169..2517278 (+)	110	Protein_2443	hypothetical protein	-
CSC56_RS13130 (CSC56_2427)	-	2517307..2517720 (+)	414	WP_001622129.1	hypothetical protein	-
CSC56_RS13135 (CSC56_2428)	-	2517898..2518884 (-)	987	WP_000999713.1	aromatic acid exporter family protein	-
CSC56_RS13145 (CSC56_2429)	map	2519527..2520285 (+)	759	WP_000636137.1	type I methionyl aminopeptidase	-
CSC56_RS13150 (CSC56_2430)	-	2520502..2520888 (+)	387	WP_001110184.1	hypothetical protein	-
CSC56_RS13155 (CSC56_2431)	liaF	2520903..2521604 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
CSC56_RS13160 (CSC56_2432)	vraS	2521601..2522644 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
CSC56_RS13165 (CSC56_2433)	vraR	2522634..2523263 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
CSC56_RS13170 (CSC56_2434)	-	2523376..2524593 (-)	1218	WP_000037083.1	YihY/virulence factor BrkB family protein	-
CSC56_RS13175 (CSC56_2435)	-	2524871..2525146 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
CSC56_RS13180 (CSC56_2436)	-	2525153..2525617 (-)	465	WP_000228668.1	low molecular weight protein-tyrosine-phosphatase	-
CSC56_RS13185 (CSC56_2437)	-	2525764..2525964 (+)	201	WP_000180459.1	DUF1128 family protein	-
CSC56_RS13190 (CSC56_2438)	-	2525976..2527223 (+)	1248	WP_000656302.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=294559 CSC56_RS13160 WP_001017131.1 2521601..2522644(+) (vraS) [Staphylococcus aureus strain AR_0471]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=294559 CSC56_RS13160 WP_001017131.1 2521601..2522644(+) (vraS) [Staphylococcus aureus strain AR_0471]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTACCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTCGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1