Detailed information NTG0294514

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: CSC57_RS09525
• Genome accession: NZ_CP029649
• Coordinates: 1896733..1897620 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain AR_0472
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1891733..1902620

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CSC57_RS09495 (CSC57_1770)	-	1892465..1893226 (+)	762	WP_000323447.1	alpha/beta hydrolase family protein	-
CSC57_RS09500 (CSC57_1771)	-	1893471..1893926 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
CSC57_RS15015	-	1894048..1894149 (+)	102	WP_000731972.1	SE2200 family small protein	-
CSC57_RS09510 (CSC57_1772)	-	1894209..1895633 (-)	1425	WP_000953762.1	alkaline phosphatase	-
CSC57_RS09515 (CSC57_1773)	-	1895831..1896031 (+)	201	WP_000604727.1	hypothetical protein	-
CSC57_RS09520 (CSC57_1774)	braR	1896057..1896722 (+)	666	WP_000697879.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
CSC57_RS09525 (CSC57_1775)	braS	1896733..1897620 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
CSC57_RS09530 (CSC57_1776)	-	1897729..1898484 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
CSC57_RS09535 (CSC57_1777)	-	1898481..1900481 (+)	2001	WP_000776739.1	ABC transporter permease	-
CSC57_RS09540	-	1901140..1901253 (+)	114	Protein_1806	hypothetical protein	-
CSC57_RS09550	-	1901635..1901895 (+)	261	WP_001789910.1	hypothetical protein	-
CSC57_RS09555 (CSC57_1778)	-	1901905..1902402 (+)	498	WP_001065269.1	glutathione peroxidase	-
CSC57_RS09560	-	1902510..1902602 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=294514 CSC57_RS09525 WP_000143420.1 1896733..1897620(+) (braS) [Staphylococcus aureus strain AR_0472]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=294514 CSC57_RS09525 WP_000143420.1 1896733..1897620(+) (braS) [Staphylococcus aureus strain AR_0472]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993