Detailed information NTG0294380

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: DLJ56_RS04200
• Genome accession: NZ_CP029629
• Coordinates: 812978..814021 (+)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain MOK063
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 807978..819021

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DLJ56_RS04165 (DLJ56_04165)	-	808519..808629 (+)	111	WP_001790257.1	hypothetical protein	-
DLJ56_RS04170 (DLJ56_04170)	-	808658..809071 (+)	414	WP_001549145.1	hypothetical protein	-
DLJ56_RS04180 (DLJ56_04180)	-	809502..810488 (-)	987	WP_000999713.1	aromatic acid exporter family protein	-
DLJ56_RS04185 (DLJ56_04185)	map	810904..811662 (+)	759	WP_000636144.1	type I methionyl aminopeptidase	-
DLJ56_RS04190 (DLJ56_04190)	-	811879..812265 (+)	387	WP_001110179.1	hypothetical protein	-
DLJ56_RS04195 (DLJ56_04195)	liaF	812280..812981 (+)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
DLJ56_RS04200 (DLJ56_04200)	vraS	812978..814021 (+)	1044	WP_001017131.1	sensor histidine kinase	Regulator
DLJ56_RS04205 (DLJ56_04205)	vraR	814011..814640 (+)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
DLJ56_RS04210 (DLJ56_04210)	-	814752..815969 (-)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
DLJ56_RS04215 (DLJ56_04215)	-	816247..816522 (-)	276	WP_000428172.1	YtxH domain-containing protein	-
DLJ56_RS04220 (DLJ56_04220)	-	816529..816993 (-)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
DLJ56_RS04225 (DLJ56_04225)	-	817140..817340 (+)	201	WP_000180463.1	DUF1128 family protein	-
DLJ56_RS04230 (DLJ56_04230)	-	817343..818599 (+)	1257	WP_001793428.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=294380 DLJ56_RS04200 WP_001017131.1 812978..814021(+) (vraS) [Staphylococcus aureus strain MOK063]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=294380 DLJ56_RS04200 WP_001017131.1 812978..814021(+) (vraS) [Staphylococcus aureus strain MOK063]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAATTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCGATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTACCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1