Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   DLJ56_RS03640 Genome accession   NZ_CP029629
Coordinates   709934..710650 (-) Length   238 a.a.
NCBI ID   WP_000688498.1    Uniprot ID   Q2VG52
Organism   Staphylococcus aureus strain MOK063     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 704934..715650
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DLJ56_RS03620 (DLJ56_03620) - 706026..706976 (+) 951 WP_000790324.1 LacI family DNA-binding transcriptional regulator -
  DLJ56_RS03625 (DLJ56_03625) - 707125..708609 (+) 1485 WP_000141426.1 sucrose-6-phosphate hydrolase -
  DLJ56_RS03630 (DLJ56_03630) - 708606..709565 (+) 960 WP_001253302.1 carbohydrate kinase -
  DLJ56_RS03635 (DLJ56_03635) - 709753..709862 (-) 110 Protein_665 hypothetical protein -
  DLJ56_RS03640 (DLJ56_03640) agrA 709934..710650 (-) 717 WP_000688498.1 quorum-sensing response regulator AgrA Regulator
  DLJ56_RS03645 (DLJ56_03645) agrC 710669..711961 (-) 1293 WP_031929881.1 quorum-sensing sensor histidine kinase AgrC -
  DLJ56_RS03650 (DLJ56_03650) agrD 711986..712126 (-) 141 WP_001093929.1 cyclic lactone autoinducer peptide AgrD -
  DLJ56_RS03655 (DLJ56_03655) agrB 712123..712692 (-) 570 WP_001105707.1 accessory gene regulator AgrB -
  DLJ56_RS14785 (DLJ56_03660) - 712928..713062 (+) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  DLJ56_RS03665 (DLJ56_03665) - 713658..714443 (-) 786 WP_000867940.1 carbon-nitrogen family hydrolase -
  DLJ56_RS03670 (DLJ56_03670) - 714804..715430 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27933.91 Da        Isoelectric Point: 6.0927

>NTDB_id=294379 DLJ56_RS03640 WP_000688498.1 709934..710650(-) (agrA) [Staphylococcus aureus strain MOK063]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSRDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=294379 DLJ56_RS03640 WP_000688498.1 709934..710650(-) (agrA) [Staphylococcus aureus strain MOK063]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTAT
TATCAAGAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCGCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q2VG52

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

99.58

100

0.996

Multiple sequence alignment