Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   EQW70_RS02995 Genome accession   NZ_CP035226
Coordinates   565450..566091 (+) Length   213 a.a.
NCBI ID   WP_003244318.1    Uniprot ID   P96686
Organism   Bacillus subtilis strain SRCM103517     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 560450..571091
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQW70_RS02965 (EQW70_02965) ydfE 561660..562283 (-) 624 WP_128740054.1 flavin reductase family protein -
  EQW70_RS02970 (EQW70_02970) ydfF 562373..563053 (+) 681 WP_003244115.1 winged helix-turn-helix domain-containing protein -
  EQW70_RS02975 (EQW70_02975) ydfG 563118..563561 (-) 444 WP_128740055.1 carboxymuconolactone decarboxylase family protein -
  EQW70_RS02980 (EQW70_02980) - 563647..563826 (-) 180 WP_010886421.1 hypothetical protein -
  EQW70_RS02985 (EQW70_02985) - 563823..563966 (-) 144 WP_014478971.1 hypothetical protein -
  EQW70_RS02990 (EQW70_02990) ydfH 564234..565457 (+) 1224 WP_128740056.1 two-component system sensor histidine kinase YdfH -
  EQW70_RS02995 (EQW70_02995) vraR 565450..566091 (+) 642 WP_003244318.1 two-component system response regulator YdfI Regulator
  EQW70_RS03000 (EQW70_03000) pleJ 566207..568381 (+) 2175 WP_128740057.1 MMPL family transporter -
  EQW70_RS03005 (EQW70_03005) cesA 568794..569696 (-) 903 WP_128740058.1 carboxylesterase -
  EQW70_RS03010 (EQW70_03010) ydfK 569899..570588 (-) 690 WP_015252719.1 DUF554 domain-containing protein -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23973.92 Da        Isoelectric Point: 5.4183

>NTDB_id=294183 EQW70_RS02995 WP_003244318.1 565450..566091(+) (vraR) [Bacillus subtilis strain SRCM103517]
MNKVLIVDDHLVVREGLKLLIETNDQYTIIGEAENGKVAVRLADELEPDIILMDLYMPEMSGLEAIKQIKEKHDTPIIIL
TTYNEDHLMIEGIELGAKGYLLKDTSSETLFHTMDAAIRGNVLLQPDILKRLQEIQFERMKKQRNETQLTEKEVIVLKAI
AKGLKSKAIAFDLGVSERTVKSRLTSIYNKLGANSRTEAVTIAMQKGILTIDN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=294183 EQW70_RS02995 WP_003244318.1 565450..566091(+) (vraR) [Bacillus subtilis strain SRCM103517]
ATGAATAAGGTTTTAATCGTTGATGACCATCTTGTCGTGAGGGAAGGTCTGAAGCTTTTAATTGAAACGAATGATCAATA
CACCATTATAGGAGAGGCGGAAAATGGAAAAGTCGCAGTCCGTCTTGCAGATGAATTAGAACCGGATATCATTCTGATGG
ATTTGTATATGCCGGAGATGAGCGGGTTAGAGGCCATTAAACAAATAAAAGAAAAACACGATACCCCCATCATTATTTTG
ACTACATATAATGAAGATCACTTAATGATCGAAGGGATTGAATTAGGAGCGAAAGGATATCTGTTAAAAGATACGAGTTC
AGAAACCCTTTTTCACACAATGGATGCAGCCATCAGAGGAAATGTGCTATTGCAGCCTGATATCCTTAAACGTCTGCAAG
AAATCCAATTTGAGCGGATGAAAAAGCAGCGCAATGAGACGCAGCTGACAGAAAAGGAAGTCATTGTTCTAAAAGCAATT
GCTAAAGGTCTTAAAAGCAAAGCGATTGCCTTTGATTTGGGCGTCTCTGAGCGAACAGTAAAGTCCAGATTAACGTCCAT
TTACAATAAATTAGGCGCGAATTCAAGAACTGAGGCAGTAACGATTGCCATGCAAAAAGGTATTCTGACAATAGACAACT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P96686

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

36.493

99.061

0.362