Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicR   Type   Regulator
Locus tag   DLJ52_RS07845 Genome accession   NZ_CP029559
Coordinates   1628526..1629233 (-) Length   235 a.a.
NCBI ID   WP_109982820.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain NIDR 6715-15     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1623526..1634233
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DLJ52_RS07830 (DLJ52_07830) - 1624621..1626060 (+) 1440 WP_109982704.1 TrkH family potassium uptake protein -
  DLJ52_RS07835 (DLJ52_07835) vicX 1626370..1627179 (-) 810 WP_109982705.1 MBL fold metallo-hydrolase Regulator
  DLJ52_RS07840 (DLJ52_07840) vicK 1627172..1628533 (-) 1362 WP_019770277.1 cell wall metabolism sensor histidine kinase VicK Regulator
  DLJ52_RS07845 (DLJ52_07845) vicR 1628526..1629233 (-) 708 WP_109982820.1 response regulator YycF Regulator
  DLJ52_RS07850 (DLJ52_07850) - 1629459..1630223 (+) 765 WP_002960993.1 amino acid ABC transporter ATP-binding protein -
  DLJ52_RS07855 (DLJ52_07855) - 1630237..1631061 (+) 825 WP_019784970.1 transporter substrate-binding domain-containing protein -
  DLJ52_RS07860 (DLJ52_07860) - 1631077..1631784 (+) 708 WP_002960990.1 amino acid ABC transporter permease -
  DLJ52_RS07865 (DLJ52_07865) - 1631799..1632449 (+) 651 WP_019790209.1 amino acid ABC transporter permease -
  DLJ52_RS07870 (DLJ52_07870) - 1633073..1633978 (-) 906 WP_002960986.1 HAD family hydrolase -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 27174.01 Da        Isoelectric Point: 4.7239

>NTDB_id=293532 DLJ52_RS07845 WP_109982820.1 1628526..1629233(-) (vicR) [Streptococcus sobrinus strain NIDR 6715-15]
MKKILVVDDEKPISDIIKFNLIKEGYEVVTAFDGKEALKRFEDENPDLIILDWMLPELEGLEVAKEIRKSSHVPIIMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELLARIKAHLRRTENIETAVAEENDASDSELTIGDLQIIPDAFVAKKRGEELEL
THREFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMKSYE

Nucleotide


Download         Length: 708 bp        

>NTDB_id=293532 DLJ52_RS07845 WP_109982820.1 1628526..1629233(-) (vicR) [Streptococcus sobrinus strain NIDR 6715-15]
ATGAAAAAGATTCTTGTTGTCGACGATGAAAAGCCGATTTCAGATATTATCAAGTTTAATTTAATTAAAGAAGGTTATGA
AGTAGTGACTGCCTTTGATGGTAAGGAAGCTTTGAAACGGTTTGAAGATGAAAATCCAGATTTGATCATCTTGGACTGGA
TGTTGCCAGAATTGGAAGGCTTAGAAGTCGCTAAAGAAATTCGCAAGAGCAGCCATGTGCCAATCATTATGCTGTCTGCC
AAGGACAGTGAGTTCGATAAGGTTATTGGTTTGGAAATTGGTGCTGATGACTATGTCACCAAGCCTTTCTCTAATCGTGA
ACTTTTGGCTCGAATCAAGGCTCACCTGCGCCGAACTGAAAACATCGAGACAGCTGTTGCTGAAGAAAACGATGCCTCGG
ATAGCGAATTAACTATTGGAGACTTACAGATTATTCCTGATGCTTTTGTTGCCAAAAAACGCGGGGAAGAGTTGGAATTG
ACCCATCGTGAATTTGAACTCCTCCATCATCTGGCTACTCATATCGGTCAAGTAATGACCCGCGAGCACCTACTGGAAAC
TGTTTGGGGTTATGACTACTTTGGTGATGTCAGAACAGTCGATGTTACTATCAGACGTCTCCGTGAGAAAATTGAGGATA
CTCCAAGCCGACCAGAATATATTTTAACCCGTCGTGGCGTTGGTTATTATATGAAGTCTTATGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicR Streptococcus mutans UA159

87.66

100

0.877
  micA Streptococcus pneumoniae Cp1015

78.112

99.149

0.774
  covR Streptococcus salivarius strain HSISS4

44.589

98.298

0.438
  covR Lactococcus lactis subsp. lactis strain DGCC12653

43.29

98.298

0.426
  scnR Streptococcus mutans UA159

38.889

99.574

0.387

Multiple sequence alignment