Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   DK182_RS09870 Genome accession   NZ_CP029491
Coordinates   2010456..2012906 (-) Length   816 a.a.
NCBI ID   WP_109833706.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain 10919     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2005456..2017906
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK182_RS09835 (DK181_09835) - 2005534..2006625 (-) 1092 WP_021673597.1 PTS fructose transporter subunit IIC -
  DK182_RS09840 (DK181_09840) - 2006638..2006955 (-) 318 WP_109833705.1 PTS fructose transporter subunit IIB -
  DK182_RS09845 (DK181_09845) - 2006972..2007448 (-) 477 Protein_1860 PTS sugar transporter subunit IIA -
  DK182_RS09850 (DK181_09850) - 2007664..2008137 (+) 474 WP_029238592.1 HTH domain-containing protein -
  DK182_RS09855 (DK181_09855) - 2008253..2008570 (+) 318 WP_231910492.1 PRD domain-containing protein -
  DK182_RS09860 (DK181_09860) - 2008625..2009572 (+) 948 WP_239415478.1 BglG family transcription antiterminator -
  DK182_RS09865 (DK181_09865) - 2009875..2010081 (-) 207 WP_019768852.1 hypothetical protein -
  DK182_RS09870 (DK181_09870) clpC 2010456..2012906 (-) 2451 WP_109833706.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  DK182_RS09875 (DK181_09875) - 2012899..2013366 (-) 468 WP_002963295.1 CtsR family transcriptional regulator -
  DK182_RS09880 (DK181_09880) tsf 2013711..2014751 (-) 1041 WP_002959773.1 translation elongation factor Ts -
  DK182_RS09885 (DK181_09885) rpsB 2014883..2015656 (-) 774 WP_002959771.1 30S ribosomal protein S2 -
  DK182_RS09890 (DK181_09890) - 2015850..2017697 (-) 1848 WP_019772438.1 APC family permease -

Sequence

Protein


Download         Length: 816 a.a.        Molecular weight: 90999.27 Da        Isoelectric Point: 6.0089

>NTDB_id=293238 DK182_RS09870 WP_109833706.1 2010456..2012906(-) (clpC) [Streptococcus sobrinus strain 10919]
MTDYSLKMQEIFSRAQYQAARYQSQFLETWHLLLAMVDTDETVAHLALLDFADQIDLDEYEDATMLVIRRKPIKVAQLNQ
VLPTSRALERILAYATRIAGAVKAPQVGSEHVLLSMMFGRDNLAARILEQVGFHFQDEGKDNLRLIDLRKVIERYAGFSK
EDVKAIFDLAKPKKSGNNNFSNMMGGPQPTTGDLADFTRDLTALAAQGQLEKVVGRDEEIMRMLQILSRKTKNNPVLVGD
AGVGKTALAYGLAQRIVEGEVPYELADFRVLELDMMSVVAGTRFRGDFEERMNQIIADIEVDGHIILFVDEVHTIMGSGS
GIDSTLDAANILKPALSRGTLHMIGATTQEEYSKHIEKDAALSRRFARVLIEEPTVDEAYQILLGLRGSYESYHNVTISD
QAVLTAVKSAHRYLTSKNLPDSAIDLLDEASAMVQNTVKRSLPTFLSSADQALLSGNLEAVAGFLKTEEDKQKIHKPVAV
REEDILRTLSKLSGIPLEKMTQADNQRYLNLEKELHKRVIGQEDAVSAVSRAIRRNQSGIRTGKRPIGSFMFLGPTGVGK
TELAKALAELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRQKPYSVLLFDEVEKAHPDIFNVLL
QVLDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKGIRQDYQAMQGRIMEELRKAYRPEFINRIDEKIVF
HSLTPDHMRQVVKLMLKPLAATLTEKQIDLKVQPAALKLLAEHGYDPEMGARPLRRTIQTEVEDRLSELLLSGQLKADSK
LKIGSHKGSLKFTIDD

Nucleotide


Download         Length: 2451 bp        

>NTDB_id=293238 DK182_RS09870 WP_109833706.1 2010456..2012906(-) (clpC) [Streptococcus sobrinus strain 10919]
ATGACTGATTATTCCCTGAAAATGCAAGAAATATTTAGCCGGGCCCAGTACCAGGCTGCCCGTTACCAAAGTCAATTTTT
GGAGACCTGGCATCTTCTTCTAGCCATGGTGGATACCGATGAGACGGTAGCTCATTTGGCTCTGCTGGATTTTGCGGATC
AAATTGATTTGGATGAATACGAGGATGCAACCATGCTGGTCATCCGTCGTAAGCCAATCAAGGTTGCTCAGCTTAATCAA
GTTTTACCGACATCAAGAGCCTTGGAGCGTATTCTGGCCTATGCCACTCGCATCGCTGGAGCTGTAAAAGCACCTCAAGT
TGGTAGTGAGCACGTTCTTTTGTCCATGATGTTTGGGCGTGACAATCTAGCCGCTAGGATTTTGGAGCAGGTCGGTTTTC
ATTTTCAAGATGAGGGCAAGGATAATCTTCGATTGATTGACCTGCGTAAAGTTATTGAGCGCTACGCAGGCTTTTCTAAG
GAAGATGTCAAGGCTATTTTTGACTTGGCCAAGCCCAAGAAATCTGGCAATAACAACTTTAGCAATATGATGGGCGGACC
TCAGCCAACAACGGGTGATTTAGCCGATTTCACCCGTGATTTGACAGCTCTAGCTGCTCAAGGTCAGCTGGAAAAGGTTG
TCGGCCGTGATGAGGAAATCATGCGGATGTTGCAAATTCTCAGCCGTAAGACCAAGAATAATCCTGTCTTGGTCGGTGAT
GCCGGTGTCGGAAAGACAGCCCTAGCTTACGGTCTGGCCCAGAGAATTGTCGAGGGAGAGGTCCCATATGAATTAGCCGA
CTTCCGAGTTTTGGAATTGGACATGATGTCAGTTGTGGCTGGTACCCGCTTTCGAGGTGACTTTGAAGAGCGCATGAATC
AGATTATTGCGGATATTGAGGTCGATGGTCATATCATCCTCTTTGTTGATGAGGTTCACACTATTATGGGCTCTGGTAGC
GGTATTGATAGCACCCTAGATGCTGCTAATATTCTTAAGCCGGCTCTTTCTAGAGGAACCCTCCACATGATTGGGGCAAC
GACCCAAGAAGAGTATTCTAAGCATATTGAAAAGGATGCCGCTCTATCTCGTCGCTTTGCTAGGGTTTTGATTGAAGAGC
CAACGGTTGATGAGGCCTATCAGATTCTATTAGGATTGAGGGGTAGCTATGAAAGTTACCATAATGTTACCATCTCTGAC
CAGGCTGTCTTAACGGCTGTTAAATCGGCCCATCGCTATTTGACCAGCAAGAACCTGCCCGATTCAGCTATTGATCTGCT
GGATGAAGCCAGTGCTATGGTACAAAATACGGTGAAACGTTCCTTGCCGACCTTTCTCAGTTCGGCTGACCAAGCCCTCC
TCTCTGGAAATCTGGAAGCCGTCGCTGGCTTCCTTAAGACGGAAGAAGATAAGCAGAAGATTCACAAGCCTGTCGCCGTC
AGGGAAGAGGACATCCTGCGGACCCTCAGCAAACTCTCAGGTATTCCGCTTGAGAAGATGACCCAGGCTGATAATCAGCG
TTACCTCAATTTGGAAAAGGAACTCCACAAGCGGGTTATCGGTCAAGAGGATGCTGTCTCAGCTGTTTCCAGAGCCATTC
GCCGTAACCAGTCGGGTATCCGGACCGGCAAGCGGCCAATCGGTTCCTTCATGTTCCTAGGGCCAACTGGGGTTGGTAAA
ACCGAGTTGGCCAAGGCCCTAGCTGAGCTCCTCTTTGATGATGAGTCAGCTCTGATTCGCTTTGATATGTCCGAGTACAT
GGAAAAATTTGCTGCCAGCCGGCTCAACGGAGCTCCTCCAGGCTATGTTGGTTACGAAGAAGGAGGCGAATTGACCGAGA
AGGTGCGCCAGAAGCCTTATTCTGTCCTCCTTTTTGATGAGGTGGAAAAGGCCCACCCTGACATCTTCAATGTCCTCCTC
CAGGTGCTGGATGATGGGGTATTGACCGACAGTCGTGGGCGCAAAGTTGATTTCTCTAATACCATCATTATCATGACCAG
CAATTTGGGGGCGACGGCTCTTCGAGATGATAAAACCGTTGGCTTTGGTGCCAAGGGCATCAGGCAGGATTACCAAGCTA
TGCAAGGACGAATTATGGAAGAACTCAGAAAAGCCTACCGGCCTGAATTCATCAATCGGATTGATGAGAAGATTGTCTTC
CACAGTTTAACACCAGACCACATGCGTCAAGTTGTTAAGTTGATGCTGAAACCACTGGCAGCTACCCTGACTGAGAAGCA
AATCGACCTTAAAGTTCAGCCAGCTGCTCTCAAACTCTTGGCTGAGCATGGTTATGATCCAGAAATGGGAGCTCGGCCTT
TACGCCGAACCATTCAAACTGAAGTTGAAGACAGATTGTCCGAATTGCTCCTGTCAGGCCAATTAAAGGCCGATTCCAAA
CTAAAAATTGGCAGCCACAAGGGCAGTCTGAAATTTACCATTGATGACTAG

Domains

Predicted by InterproScan.

Clp amino terminal domain, pathogenicity island component (Clp_N)

(18-44)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(105-133)

ATPase family associated with various cellular activities (AAA) (AAA)

(236-369)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(723-802)

AAA domain (Cdc48 subfamily) (AAA_2)

(545-716)

AAA lid domain (AAA_lid_9)

(375-440)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus mutans UA159

71.166

99.877

0.711
  clpC Streptococcus thermophilus LMD-9

69.645

100

0.697
  clpC Streptococcus thermophilus LMG 18311

69.645

100

0.697
  clpC Streptococcus pneumoniae TIGR4

65.479

99.755

0.653
  clpC Streptococcus pneumoniae Rx1

65.356

99.755

0.652
  clpC Streptococcus pneumoniae D39

65.356

99.755

0.652
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

48.868

100

0.502
  clpC Bacillus subtilis subsp. subtilis str. 168

45.41

100

0.455
  clpE Streptococcus pneumoniae Rx1

46.047

79.044

0.364
  clpE Streptococcus pneumoniae D39

46.047

79.044

0.364
  clpE Streptococcus pneumoniae R6

46.047

79.044

0.364
  clpE Streptococcus pneumoniae TIGR4

45.963

78.922

0.363

Multiple sequence alignment