Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   DK181_RS10105 Genome accession   NZ_CP029490
Coordinates   2058495..2060945 (-) Length   816 a.a.
NCBI ID   WP_019789562.1    Uniprot ID   -
Organism   Streptococcus sobrinus strain SL1     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 2053495..2065945
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DK181_RS10070 (DK182_10070) - 2053502..2053804 (-) 303 WP_002960752.1 PTS fructose transporter subunit IIB -
  DK181_RS10075 (DK182_10075) - 2053986..2054425 (-) 440 Protein_1920 PTS sugar transporter subunit IIA -
  DK181_RS10080 (DK182_10080) - 2054536..2055471 (-) 936 WP_019773382.1 IS30 family transposase -
  DK181_RS10085 (DK182_10085) - 2055702..2056175 (+) 474 WP_028798448.1 HTH domain-containing protein -
  DK181_RS10090 (DK182_10090) - 2056291..2056608 (+) 318 WP_231910492.1 PRD domain-containing protein -
  DK181_RS10095 (DK182_10095) - 2056663..2057496 (+) 834 WP_269460058.1 BglG family transcription antiterminator -
  DK181_RS11020 - 2057411..2057611 (+) 201 WP_176621499.1 PTS sugar transporter subunit IIA -
  DK181_RS10100 (DK182_10100) - 2057914..2058120 (-) 207 WP_019772845.1 hypothetical protein -
  DK181_RS10105 (DK182_10105) clpC 2058495..2060945 (-) 2451 WP_019789562.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  DK181_RS10110 (DK182_10110) - 2060938..2061405 (-) 468 WP_002963295.1 CtsR family transcriptional regulator -
  DK181_RS10115 (DK182_10115) tsf 2061750..2062790 (-) 1041 WP_002959773.1 translation elongation factor Ts -
  DK181_RS10120 (DK182_10120) rpsB 2062922..2063695 (-) 774 WP_002959771.1 30S ribosomal protein S2 -
  DK181_RS10125 (DK182_10125) - 2063889..2065736 (-) 1848 WP_002959770.1 APC family permease -

Sequence

Protein


Download         Length: 816 a.a.        Molecular weight: 90967.23 Da        Isoelectric Point: 6.0089

>NTDB_id=293184 DK181_RS10105 WP_019789562.1 2058495..2060945(-) (clpC) [Streptococcus sobrinus strain SL1]
MTDYSLKMQEIFSRAQYQAARYQSQFLETWHLLLAMVDTDETVAHLALLDFADQIDLDEYEDATMLVIRRKPIKVAQLNQ
VLPTSRALERILAYATRIAGAVKAPQVGSEHVLLSMMFGRDNLAARILEQVGFHFQDEGKDNLRLIDLRKVIERYAGFSK
EDVKAIFDLAKPKKSGNNNFSNMMGGPQPTTGDLADFTRDLTALAAQGQLEKVVSRDEEIMRMLQILSRKTKNNPVLVGD
AGVGKTALAYGLAQRIVEGEVPYELADFRVLELDMMSVVAGTRFRGDFEERMNQIIADIEADGHIILFVDEVHTIMGSGS
GIDSTLDAANILKPALSRGTLHMIGATTQEEYSKHIEKDAALSRRFARVLIEEPTVDEAYQILLGLRGSYESYHNVTISD
QAVLTAVKSAHRYLTSKNLPDSAIDLLDEASAMVQNTVKRSLPTFLSSADQALLSGNLEAVAGLLKTEEDKQKIHKPVAV
REEDILRTLSKLSGIPLEKMTQADNQRYLNLEKELHKRVIGQEDAVSAVSRAIRRNQSGIRTGKRPIGSFMFLGPTGVGK
TELAKALAELLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRQKPYSVLLFDEVEKAHPDIFNVLL
QVLDDGVLTDSRGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKGIRQDYQAMQGRIMEELRKAYRPEFINRIDEKIVF
HSLTPDHMRQVVKLMLKPLAATLTEKQIDLKVQPAALKLLAEHGYDPEMGARPLRRTIQTEVEDRLSELLLSGQLKADSK
LKIGSHKGSLKFTIDD

Nucleotide


Download         Length: 2451 bp        

>NTDB_id=293184 DK181_RS10105 WP_019789562.1 2058495..2060945(-) (clpC) [Streptococcus sobrinus strain SL1]
ATGACTGATTATTCCCTGAAAATGCAAGAAATATTTAGCCGGGCCCAGTACCAGGCTGCCCGTTACCAAAGTCAATTTTT
GGAGACCTGGCATCTTCTTCTAGCCATGGTGGATACCGATGAGACGGTAGCTCATTTGGCTCTGCTGGATTTTGCGGATC
AAATTGATTTGGATGAATACGAGGATGCAACCATGCTGGTCATCCGTCGTAAGCCAATCAAGGTTGCTCAGCTTAATCAA
GTTTTACCGACATCAAGAGCCTTGGAGCGTATTCTGGCCTATGCCACTCGCATCGCTGGAGCTGTAAAAGCACCTCAAGT
TGGTAGTGAGCACGTTCTTTTGTCCATGATGTTTGGGCGTGACAATCTAGCCGCTAGGATTTTGGAGCAGGTCGGTTTTC
ATTTTCAAGATGAGGGCAAGGATAATCTTCGATTGATTGACCTGCGCAAAGTTATTGAGCGCTACGCAGGCTTTTCTAAG
GAAGATGTCAAGGCTATTTTTGACTTGGCCAAGCCCAAGAAATCTGGCAATAACAACTTTAGCAATATGATGGGCGGACC
TCAGCCAACAACGGGTGATTTAGCCGATTTCACCCGTGATTTGACAGCTCTAGCTGCTCAAGGTCAGCTGGAAAAGGTTG
TCAGCCGTGATGAGGAAATCATGCGGATGTTGCAAATTCTCAGCCGTAAGACCAAGAATAATCCTGTCTTGGTCGGTGAT
GCCGGTGTCGGAAAGACAGCCCTAGCTTACGGTCTGGCCCAGAGAATTGTCGAGGGAGAGGTCCCATATGAATTAGCCGA
CTTCCGAGTTTTGGAATTGGACATGATGTCAGTTGTGGCTGGTACCCGCTTTCGAGGTGACTTTGAAGAGCGCATGAATC
AGATTATTGCGGATATTGAGGCCGATGGTCATATCATCCTCTTTGTTGATGAGGTTCACACTATTATGGGCTCTGGTAGC
GGTATTGATAGCACCCTAGATGCTGCTAATATTCTTAAGCCGGCTCTTTCTAGAGGAACCCTCCACATGATTGGGGCAAC
GACCCAAGAAGAGTATTCTAAGCATATTGAAAAGGATGCCGCTCTATCTCGTCGCTTTGCTAGGGTTTTGATTGAAGAGC
CAACGGTTGATGAGGCCTATCAGATTCTATTAGGATTGAGGGGTAGCTATGAAAGTTACCATAATGTTACCATCTCTGAC
CAGGCTGTCTTAACGGCTGTCAAATCGGCCCATCGCTATTTGACCAGCAAGAACCTGCCCGATTCAGCTATTGATCTGCT
GGATGAAGCCAGTGCTATGGTACAAAATACGGTGAAACGTTCCTTGCCGACCTTTCTCAGTTCGGCTGACCAAGCCCTCC
TCTCTGGAAATCTGGAAGCCGTCGCTGGCCTCCTTAAGACGGAAGAAGATAAGCAGAAGATTCACAAGCCTGTCGCCGTC
AGGGAAGAGGACATCCTGCGGACCCTCAGCAAACTCTCAGGTATTCCGCTTGAGAAGATGACCCAGGCTGATAATCAGCG
TTACCTCAATTTGGAAAAGGAACTCCACAAGCGGGTTATCGGTCAAGAGGATGCTGTCTCAGCTGTTTCCAGAGCCATTC
GCCGTAACCAGTCGGGTATCCGGACCGGCAAGCGGCCAATCGGTTCCTTCATGTTCCTAGGGCCAACTGGGGTTGGTAAA
ACCGAGTTGGCCAAGGCCCTAGCTGAGCTCCTCTTTGATGATGAGTCAGCTCTGATTCGCTTTGATATGTCCGAGTACAT
GGAAAAATTTGCTGCCAGCCGGCTCAACGGAGCTCCTCCAGGCTATGTTGGTTACGAAGAAGGAGGCGAATTGACCGAGA
AGGTGCGCCAGAAGCCTTATTCTGTCCTCCTTTTTGATGAGGTGGAAAAGGCCCACCCTGACATCTTCAATGTCCTCCTC
CAGGTGCTGGATGATGGGGTATTGACCGACAGTCGTGGGCGCAAAGTTGATTTCTCTAATACCATCATTATCATGACCAG
CAATTTGGGGGCGACGGCTCTTCGAGATGATAAAACCGTTGGCTTTGGTGCCAAGGGCATCAGGCAGGATTACCAAGCTA
TGCAAGGACGAATTATGGAAGAACTCAGAAAAGCCTACCGGCCTGAATTCATCAATCGGATTGATGAGAAGATTGTCTTC
CACAGTTTAACACCAGACCACATGCGTCAAGTTGTTAAGTTGATGCTGAAACCACTGGCAGCTACCCTGACTGAGAAGCA
AATCGACCTTAAAGTTCAGCCAGCTGCTCTCAAACTCTTGGCTGAGCATGGTTATGATCCAGAAATGGGAGCTCGGCCTT
TACGCCGAACCATTCAAACTGAAGTTGAAGACAGATTGTCCGAATTGCTCCTGTCAGGCCAATTAAAGGCCGATTCCAAA
CTAAAAATTGGCAGCCACAAGGGCAGTCTGAAATTTACCATTGATGACTAG

Domains

Predicted by InterproScan.

Clp amino terminal domain, pathogenicity island component (Clp_N)

(18-44)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(105-133)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(723-802)

AAA lid domain (AAA_lid_9)

(375-440)

ATPase family associated with various cellular activities (AAA) (AAA)

(236-369)

AAA domain (Cdc48 subfamily) (AAA_2)

(545-716)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus mutans UA159

71.288

99.877

0.712
  clpC Streptococcus thermophilus LMD-9

69.645

100

0.697
  clpC Streptococcus thermophilus LMG 18311

69.645

100

0.697
  clpC Streptococcus pneumoniae TIGR4

65.479

99.755

0.653
  clpC Streptococcus pneumoniae Rx1

65.356

99.755

0.652
  clpC Streptococcus pneumoniae D39

65.356

99.755

0.652
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

48.868

100

0.502
  clpC Bacillus subtilis subsp. subtilis str. 168

45.41

100

0.455
  clpE Streptococcus pneumoniae Rx1

45.929

79.779

0.366
  clpE Streptococcus pneumoniae D39

45.929

79.779

0.366
  clpE Streptococcus pneumoniae R6

45.929

79.779

0.366
  clpE Streptococcus pneumoniae TIGR4

45.846

79.657

0.365
  clpE Streptococcus mutans UA159

46.741

77.083

0.36

Multiple sequence alignment