Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   DKG78_RS06415 Genome accession   NZ_CP029466
Coordinates   1238974..1239630 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus amyloliquefaciens strain HM618     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1233974..1244630
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DKG78_RS06385 (DKG78_06495) oppF 1234503..1235420 (+) 918 WP_012117283.1 oligopeptide ABC transporter ATP-binding protein OppF -
  DKG78_RS06390 (DKG78_06500) - 1235527..1236723 (+) 1197 WP_192452946.1 putative glycoside hydrolase -
  DKG78_RS06395 (DKG78_06505) - 1236832..1237410 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  DKG78_RS06400 (DKG78_06510) spx 1237589..1237984 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  DKG78_RS06405 (DKG78_06515) - 1238042..1238698 (-) 657 WP_192452947.1 TerC family protein -
  DKG78_RS06415 (DKG78_06520) mecA 1238974..1239630 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  DKG78_RS06420 (DKG78_06525) - 1239781..1240941 (+) 1161 WP_192452948.1 competence protein CoiA family protein -
  DKG78_RS06425 (DKG78_06530) pepF 1241169..1242998 (+) 1830 WP_007409107.1 oligoendopeptidase F Regulator
  DKG78_RS06430 - 1243036..1243203 (-) 168 WP_192452949.1 hypothetical protein -
  DKG78_RS06435 (DKG78_06535) spxH 1243489..1244391 (-) 903 WP_032874464.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=292799 DKG78_RS06415 WP_003155032.1 1238974..1239630(+) (mecA) [Bacillus amyloliquefaciens strain HM618]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=292799 DKG78_RS06415 WP_003155032.1 1238974..1239630(+) (mecA) [Bacillus amyloliquefaciens strain HM618]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment