Detailed information NTG0292295

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: DF184_RS09535
• Genome accession: NZ_CP029398
• Coordinates: 1941619..1944072 (-)
• Length: 817 a.a.
• NCBI ID: WP_024388241.1
• Uniprot ID: -
• Organism: Streptococcus suis strain HN105
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 1936619..1949072

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DF184_RS09520 (DF184_09520)	hslO	1939050..1939916 (+)	867	WP_109371977.1	Hsp33 family molecular chaperone HslO	-
DF184_RS09525 (DF184_09525)	dusB	1939909..1940913 (+)	1005	WP_109371979.1	tRNA dihydrouridine synthase DusB	-
DF184_RS09530 (DF184_09530)	-	1941009..1941500 (-)	492	WP_044680265.1	adenylyltransferase/cytidyltransferase family protein	-
DF184_RS09535 (DF184_09535)	clpC	1941619..1944072 (-)	2454	WP_024388241.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
DF184_RS09540 (DF184_09540)	-	1944076..1944534 (-)	459	WP_002937810.1	CtsR family transcriptional regulator	-
DF184_RS09545 (DF184_09545)	-	1944805..1945143 (+)	339	WP_044680266.1	thioredoxin domain-containing protein	-
DF184_RS09550 (DF184_09550)	-	1945143..1945844 (+)	702	WP_044680268.1	hypothetical protein	-
DF184_RS09555 (DF184_09555)	tsf	1946001..1947041 (-)	1041	WP_002937816.1	translation elongation factor Ts	-
DF184_RS09560 (DF184_09560)	rpsB	1947421..1948197 (-)	777	WP_012775356.1	30S ribosomal protein S2	-

Sequence

Protein

• Length: 817 a.a.
• Molecular weight: 90444.99 Da
• Isoelectric Point: 6.2908

>NTDB_id=292295 DF184_RS09535 WP_024388241.1 1941619..1944072(-) (clpC) [Streptococcus suis strain HN105]
MKISTGLQRVFEDAQLVAQRYACDYLETWHVLLSFVINHDTVAGAVLAEYPISISDYEHATFVVTDKVYREELDSFRILP
SSKRLDETASFAKKIAEVVKAKELGTEHLFMAMLLDKRSTASQILDKVGFCFEDSDDKFRFLDLRKNLEARAGFTKEDLK
AIRSVMKGGKAKPTNMGQMMGMPPAPQSGGLEDYTRDLTALAREGKIEPVIGRDAEIARMIQILSRKTKNNPVLVGDAGV
GKTALALGLAQRVAAGDVPVSLAKMRVLELDLMNVIAGTRFRGDFEERMNNIINDIEEDGQVILFIDELHTIMGSGSGID
STLDAANILKPALARGTLRTVGATTQTEYQKHIEKDAALVRRFAKVTIEEPTVEDSIAILTGLKGTFEKYHRVRIGQAAV
ETAVTYAKRYLTSKNLPDSAIDLLDEASATVQNRVKGQAEETGLTSIDKALMDKKYKTVSKLLIKTKEDAEASQNYDLEV
TEEDVLETLSRLSGIPVAKLSQSDTKKYLNLEAELHKRVIGQEEAISAVSRAIRRNQSGIRTGRRPIGSFMFLGPTGVGK
TELAKALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLL
QVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGALDLSKDHKEVEKRIFEELKKAYRPEFINRIDEKVVF
HSLTETHMQDVVKVMIKPLLAVTAEKGITLKLQPSALKLLAKQGYDPEMGARPLRRLLQTKLEDPLAEMLLRGDLTTGST
LKVGVKGEELKFDVVKG

Nucleotide

• Length: 2454 bp

>NTDB_id=292295 DF184_RS09535 WP_024388241.1 1941619..1944072(-) (clpC) [Streptococcus suis strain HN105]
ATGAAAATTTCAACTGGTTTACAGCGGGTTTTTGAAGATGCCCAGTTAGTGGCCCAACGTTATGCCTGTGATTACTTGGA
AACCTGGCATGTTCTCTTGTCTTTCGTTATCAACCATGATACAGTCGCTGGCGCTGTTTTGGCAGAATATCCTATTTCAA
TTTCTGACTATGAACATGCAACTTTTGTTGTGACCGACAAGGTCTATCGTGAAGAGTTGGATAGTTTTCGTATTTTACCA
TCTTCTAAACGTTTGGATGAAACGGCTAGTTTTGCCAAGAAAATTGCAGAAGTCGTCAAGGCTAAGGAGCTGGGAACGGA
ACATTTGTTTATGGCTATGTTGTTGGACAAGCGGTCAACAGCTAGTCAGATTTTGGACAAGGTAGGTTTTTGTTTTGAAG
ACTCAGATGATAAGTTTCGTTTCTTGGATTTGCGTAAAAACTTGGAGGCACGTGCGGGATTTACCAAAGAGGACCTTAAA
GCTATCCGCAGTGTGATGAAGGGTGGCAAAGCCAAACCTACCAATATGGGACAGATGATGGGAATGCCCCCAGCACCTCA
AAGTGGTGGATTAGAAGACTACACTCGTGATTTGACAGCTTTGGCGCGTGAAGGGAAGATTGAACCTGTTATCGGTCGAG
ACGCTGAGATTGCACGGATGATCCAAATTCTATCACGTAAAACCAAGAACAACCCAGTTCTAGTTGGTGATGCTGGTGTC
GGAAAAACTGCGCTTGCTTTGGGTCTTGCTCAACGTGTTGCTGCAGGTGATGTCCCTGTCAGCTTGGCTAAGATGCGGGT
TTTGGAACTTGACTTGATGAACGTTATCGCTGGAACTCGTTTCCGTGGTGATTTCGAAGAGCGGATGAATAATATCATCA
ACGACATCGAGGAAGATGGTCAGGTCATCCTTTTCATCGATGAGTTGCATACCATTATGGGTTCTGGCTCGGGGATTGAT
TCGACCTTGGATGCAGCCAATATCCTCAAACCAGCTCTTGCTCGTGGCACCCTCCGTACGGTCGGAGCGACGACTCAGAC
AGAGTACCAAAAGCATATTGAGAAAGATGCAGCCCTGGTTCGTCGTTTTGCCAAAGTGACCATTGAAGAGCCGACAGTGG
AAGATAGCATTGCCATTTTGACTGGTTTAAAAGGTACTTTTGAAAAATACCACAGGGTCCGTATTGGACAAGCAGCTGTA
GAGACTGCTGTGACCTACGCTAAGCGGTATTTGACCAGTAAAAACCTACCGGATTCAGCCATTGATCTGCTGGATGAAGC
CAGTGCAACGGTACAAAATCGAGTGAAAGGGCAGGCTGAGGAAACAGGACTGACGAGCATAGACAAGGCCTTGATGGATA
AAAAATATAAGACTGTCAGCAAGCTGTTGATTAAAACGAAAGAAGATGCCGAGGCTAGTCAAAACTATGACCTTGAAGTA
ACAGAAGAAGATGTTTTAGAAACACTTAGCCGCTTGTCAGGTATCCCAGTAGCCAAGCTTAGCCAATCAGATACTAAGAA
GTATCTGAATCTGGAAGCAGAATTGCATAAGCGTGTGATTGGGCAGGAAGAAGCTATTTCTGCTGTTAGCAGAGCTATTC
GCCGTAATCAGTCAGGGATTCGTACAGGTCGCAGACCGATTGGTTCCTTTATGTTCTTGGGACCGACTGGTGTCGGTAAG
ACAGAGCTTGCTAAAGCCTTGGCGGAGGTTCTCTTTGATGATGAATCTGCTCTTATCCGTTTTGATATGTCTGAGTATAT
GGAGAAATTTGCGGCCAGCCGTCTCAATGGAGCGCCTCCAGGTTACGTGGGCTATGAAGAAGGTGGCGAATTGACGGAAA
AAGTTCGTAACAAACCTTATTCTGTTCTTCTTTTTGATGAGGTTGAAAAGGCTCATCCAGATATTTTCAATGTTCTCTTG
CAGGTCTTGGATGATGGTGTTCTGACGGACAGTAAGGGACGTAAGGTTGATTTCTCAAATACTATTATTATCATGACGTC
AAACCTTGGAGCAACAGCCCTTCGTGATGATAAGACAGTTGGTTTTGGTGCCCTTGATTTATCTAAGGACCACAAGGAAG
TGGAGAAACGCATTTTTGAGGAATTGAAAAAAGCCTATCGTCCAGAATTTATCAACCGTATTGACGAGAAAGTTGTCTTC
CATAGCCTAACGGAAACTCATATGCAGGATGTTGTCAAGGTCATGATTAAACCTTTGTTGGCTGTAACAGCTGAGAAAGG
AATTACTCTTAAACTGCAACCGTCAGCCCTTAAGTTATTGGCTAAACAAGGTTATGACCCAGAAATGGGGGCTCGTCCTC
TTCGTAGACTCTTGCAGACCAAGTTGGAAGATCCATTGGCAGAGATGTTGCTCCGTGGTGACTTGACTACTGGTTCGACC
TTGAAGGTTGGGGTCAAGGGTGAAGAGCTCAAGTTTGATGTGGTAAAGGGATAA

Domains

Predicted by InterproScan.

• AAA lid domain (AAA_lid_9) (372-457)

• ATPase family associated with various cellular activities (AAA) (AAA) (233-365)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (102-129)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (14-56)

• AAA domain (Cdc48 subfamily) (AAA_2) (545-716)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (723-803)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae Rx1	71.902	99.755	0.717
clpC	Streptococcus pneumoniae D39	71.902	99.755	0.717
clpC	Streptococcus pneumoniae TIGR4	71.902	99.755	0.717
clpC	Streptococcus mutans UA159	66.708	99.633	0.665
clpC	Streptococcus thermophilus LMD-9	63.962	100	0.656
clpC	Streptococcus thermophilus LMG 18311	64.38	100	0.655
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.222	100	0.503
clpC	Bacillus subtilis subsp. subtilis str. 168	43.353	100	0.443