Detailed information NTG0292268

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: DF184_RS02580
• Genome accession: NZ_CP029398
• Coordinates: 499394..501622 (-)
• Length: 742 a.a.
• NCBI ID: WP_109371211.1
• Uniprot ID: -
• Organism: Streptococcus suis strain HN105
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 494394..506622

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DF184_RS02560 (DF184_02560)	-	494828..495271 (+)	444	WP_044761895.1	GNAT family N-acetyltransferase	-
DF184_RS02565 (DF184_02565)	ileS	495282..498071 (+)	2790	WP_109371209.1	isoleucine--tRNA ligase	-
DF184_RS02570 (DF184_02570)	-	498384..498692 (-)	309	WP_002938710.1	DUF1827 family protein	-
DF184_RS02575 (DF184_02575)	-	498747..499208 (-)	462	WP_002938708.1	NUDIX hydrolase	-
DF184_RS02580 (DF184_02580)	clpE	499394..501622 (-)	2229	WP_109371211.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
DF184_RS02585 (DF184_02585)	-	501845..502075 (+)	231	WP_002938704.1	DUF1797 family protein	-
DF184_RS02590 (DF184_02590)	-	502201..502890 (+)	690	WP_002938702.1	amino acid ABC transporter permease	-
DF184_RS02595 (DF184_02595)	-	502883..503617 (+)	735	WP_002943067.1	amino acid ABC transporter ATP-binding protein	-
DF184_RS02600 (DF184_02600)	-	503747..504595 (+)	849	WP_024385039.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-

Sequence

Protein

• Length: 742 a.a.
• Molecular weight: 82784.25 Da
• Isoelectric Point: 5.4411

>NTDB_id=292268 DF184_RS02580 WP_109371211.1 499394..501622(-) (clpE) [Streptococcus suis strain HN105]
MLCKNCNINDATIHLYTNLNGKQQQVDLCHNCYQIMKTDPNNAILRGLGDLTNPNNMDPFSEFFNHLGRYPGNTPAGKNR
EQTPPTQAGGHNGRGGQTPPPQQPQQPNGLLEEFGINVTEIARRGDIDPVIGRDQEITRVIEILNRRTKNNPVLIGEPGV
GKTAVVEGLAQKIVDGDVPQKLRDKEVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRNRREIILFIDEIHEIVGAGSAGD
GNMDAGNILKPALARGEMQLVGATTLNEYRIIEKDAALERRMQPVKVEEPSVEETITILKGIQNKYQDYHHVKYSDAAIE
AAAVLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFIDPKEIDQRLIDAENRKAQATRDEDYEKAAYFRDQIAKYKEMQK
ATISEEDIPLITEKEIEAIVEQKTNIPVGDLKEKEQSQLVNLASDLKARVIGQDEAVDKIAKAIRRNRVGLGAPNRPIGS
FLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPYSLILLDEVE
KAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKVEASVGFGAAMEGRTQSVLGQLSNFFTPEFMNRFDG
IIEFQPLSKENLLEIVSLMLDDVNKRLSHNGIRLHVTDKVKEKLVDLGYDPKMGARPLRRTIQDQIEDAITDFYLEHPAE
KDLRAVMSSKGTIQIKAQTKTK

Nucleotide

• Length: 2229 bp

>NTDB_id=292268 DF184_RS02580 WP_109371211.1 499394..501622(-) (clpE) [Streptococcus suis strain HN105]
ATGCTCTGCAAAAATTGTAATATCAACGACGCAACGATCCATCTCTACACCAACTTAAACGGTAAACAACAGCAGGTAGA
CCTCTGTCACAACTGCTATCAAATCATGAAAACAGACCCTAATAATGCTATCCTACGTGGGTTAGGAGATTTAACAAATC
CTAACAATATGGATCCCTTTAGTGAATTCTTCAATCACCTAGGTCGCTATCCTGGCAATACCCCTGCTGGAAAAAATCGC
GAACAGACTCCTCCAACTCAAGCCGGTGGGCATAATGGACGTGGTGGACAGACCCCTCCTCCGCAACAACCCCAACAACC
AAATGGGCTCCTTGAAGAATTTGGTATCAACGTTACCGAAATTGCCCGTCGTGGGGATATTGATCCAGTAATCGGTCGCG
ATCAAGAGATTACCCGTGTCATCGAAATTCTCAACCGTCGTACAAAAAATAACCCTGTTCTTATCGGTGAGCCTGGAGTA
GGTAAAACAGCGGTTGTTGAAGGCTTGGCTCAAAAAATTGTCGATGGCGATGTCCCACAGAAATTACGAGACAAGGAAGT
CATTCGTCTGGATGTTGTCAGCCTCGTACAAGGAACAGGTATCCGCGGACAATTTGAAGAACGCATGCAAAAACTCATGG
AAGAAATCCGTAATCGTCGCGAAATCATTCTTTTTATTGACGAGATTCACGAAATTGTCGGTGCTGGTTCTGCAGGCGAT
GGCAACATGGATGCTGGCAATATCCTCAAACCAGCCCTCGCACGTGGTGAAATGCAACTAGTCGGTGCAACAACGCTCAA
CGAATACCGTATTATCGAAAAAGATGCCGCCCTAGAGCGCCGTATGCAACCTGTAAAAGTTGAAGAACCAAGTGTCGAAG
AAACTATTACCATTCTCAAAGGTATCCAAAATAAATACCAGGATTACCATCATGTTAAATACTCCGATGCTGCTATCGAA
GCTGCCGCAGTACTGTCCAACCGCTACATTCAAGACCGTTTCCTACCAGACAAGGCTATTGACCTTCTGGATGAAGCTGG
TTCAAAAATGAATTTGACCCTCAACTTTATTGATCCAAAAGAAATTGACCAACGCCTGATTGATGCCGAAAATCGTAAAG
CACAAGCTACACGGGATGAGGACTATGAGAAAGCGGCCTATTTCCGTGACCAAATTGCTAAGTACAAGGAGATGCAAAAG
GCAACTATCAGCGAGGAAGATATTCCACTCATTACTGAGAAAGAAATTGAGGCCATCGTTGAGCAAAAAACAAATATCCC
AGTTGGTGATTTAAAAGAAAAGGAACAGTCCCAGCTTGTGAACCTCGCTAGTGACTTAAAAGCCCGTGTTATCGGACAAG
ATGAAGCAGTTGACAAGATAGCTAAAGCCATCCGCCGTAATCGTGTCGGTCTCGGTGCTCCAAATCGTCCAATTGGATCC
TTCCTCTTTGTCGGACCAACAGGTGTCGGTAAAACCGAATTGTCTAAGCAATTAGCTATCGAACTCTTCGGTTCGGCGGA
CAGCATGATCCGCTTCGACATGTCCGAATACATGGAAAAACACGCTGTCGCTAAACTCGTCGGAGCTCCTCCAGGCTATG
TAGGCTATGAGGAGGCTGGACAATTGACTGAAAAAGTCCGTCGTAATCCTTATTCACTCATCCTCCTTGACGAAGTTGAA
AAAGCCCACCCAGATGTCATGCACATGTTCCTTCAGGTCTTAGACGATGGGCGTCTGACAGATGGACAAGGTCGTACTGT
CAGCTTCAAAGATACCATCATCATCATGACATCAAATGCTGGTACTGGAAAAGTTGAAGCAAGTGTCGGTTTTGGTGCGG
CTATGGAAGGGCGGACTCAATCAGTCCTTGGCCAACTTAGCAATTTCTTCACACCTGAATTTATGAACCGATTTGACGGC
ATTATTGAGTTCCAACCACTGAGCAAGGAAAACCTACTTGAAATCGTCAGCCTCATGCTAGACGATGTAAACAAACGCCT
TTCTCACAATGGCATCCGCCTCCATGTAACAGATAAAGTTAAGGAGAAATTAGTGGACCTTGGCTACGATCCAAAGATGG
GAGCTCGTCCACTACGCAGAACCATCCAAGATCAGATTGAAGATGCTATCACCGACTTCTACTTAGAACATCCAGCAGAA
AAAGACCTACGTGCTGTCATGTCAAGTAAAGGTACAATTCAAATCAAGGCACAAACAAAGACAAAATAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (647-721)

• AAA domain (Cdc48 subfamily) (AAA_2) (476-639)

• AAA lid domain (AAA_lid_9) (291-389)

• ATPase family associated with various cellular activities (AAA) (AAA) (153-272)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	82.361	100	0.837
clpE	Streptococcus pneumoniae D39	82.361	100	0.837
clpE	Streptococcus pneumoniae R6	82.361	100	0.837
clpE	Streptococcus pneumoniae TIGR4	82.361	100	0.837
clpE	Streptococcus mutans UA159	82.353	100	0.83
clpC	Lactococcus lactis subsp. cremoris KW2	77.517	97.709	0.757
clpC	Bacillus subtilis subsp. subtilis str. 168	52.462	87.601	0.46
clpC	Streptococcus mutans UA159	48.718	84.097	0.41
clpC	Streptococcus thermophilus LMD-9	48.248	84.636	0.408
clpC	Streptococcus thermophilus LMG 18311	47.93	84.636	0.406
clpC	Streptococcus pneumoniae Rx1	48	84.232	0.404
clpC	Streptococcus pneumoniae D39	48	84.232	0.404
clpC	Streptococcus pneumoniae TIGR4	48	84.232	0.404
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	46.975	84.636	0.398