Detailed information NTG0291648

Bioinformatically predicted

Overview

• Name: spo0A
• Type: Regulator
• Locus tag: DIR45_RS21055
• Genome accession: NZ_CP029323
• Coordinates: 3993894..3994688 (-)
• Length: 264 a.a.
• NCBI ID: WP_003161566.1
• Uniprot ID: P52928
• Organism: Bacillus anthracis strain 17OD930
• Function: activation and repression of comK; repression of rok; repression of abrB (predicted from homology) Competence regulation

Genomic Context

Location: 3988894..3999688

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DIR45_RS21035 (DIR45_22145)	-	3990695..3990928 (+)	234	WP_001190187.1	DUF2627 domain-containing protein	-
DIR45_RS21040 (DIR45_22150)	-	3990977..3991705 (-)	729	WP_000172562.1	glycerophosphodiester phosphodiesterase	-
DIR45_RS21045 (DIR45_22155)	-	3991756..3991902 (+)	147	WP_001247671.1	YycC family protein	-
DIR45_RS21050 (DIR45_22160)	-	3992070..3993596 (-)	1527	WP_000218387.1	glycosyltransferase family 39 protein	-
DIR45_RS21055 (DIR45_22165)	spo0A	3993894..3994688 (-)	795	WP_003161566.1	sporulation transcription factor Spo0A	Regulator
DIR45_RS21065 (DIR45_22175)	spoIVB	3994976..3996274 (-)	1299	WP_003172258.1	SpoIVB peptidase	-
DIR45_RS21070 (DIR45_22180)	recN	3996393..3998132 (-)	1740	WP_000947756.1	DNA repair protein RecN	Machinery gene
DIR45_RS21075 (DIR45_22185)	argR	3998400..3998849 (-)	450	WP_001032581.1	arginine repressor ArgR	-

Sequence

Protein

• Length: 264 a.a.
• Molecular weight: 29440.17 Da
• Isoelectric Point: 7.4718

>NTDB_id=291648 DIR45_RS21055 WP_003161566.1 3993894..3994688(-) (spo0A) [Bacillus anthracis strain 17OD930]
MEKIKVCLVDDNKELVSMLESYVAAQDDMEVIGTAYNGQECLNLLKDKQPDVLVLDIIMPHLDGLAVLEKMRHIERLRQP
SVIMLTAFGQEDVTKKAVDLGASYFILKPFDMENLTSHIRQVSGKANATIKRPLPSFRSATTVDGKPKNLDASITSIIHE
IGVPAHIKGYMYLREAISMVYNDIELLGSITKVLYPDIAKKYNTTASRVERAIRHAIEVAWSRGNIDSISSLFGYTVSMS
KAKPTNSEFIAMVADKLRLEHKAS

Nucleotide

• Length: 795 bp

>NTDB_id=291648 DIR45_RS21055 WP_003161566.1 3993894..3994688(-) (spo0A) [Bacillus anthracis strain 17OD930]
GTGGAGAAAATTAAAGTATGTCTTGTGGATGATAATAAAGAATTAGTATCAATGCTAGAGAGTTATGTAGCTGCTCAAGA
TGATATGGAAGTAATCGGTACTGCTTATAATGGTCAAGAGTGTTTAAATTTATTAAAAGATAAGCAGCCGGATGTACTCG
TATTGGATATTATTATGCCACATTTAGATGGTTTAGCTGTACTAGAGAAAATGCGACATATTGAAAGGTTAAGACAGCCT
AGCGTAATTATGTTGACAGCATTTGGACAAGAAGATGTGACGAAAAAAGCAGTTGACTTAGGTGCTTCATATTTCATATT
AAAACCATTTGATATGGAAAATTTAACGAGTCATATTCGTCAAGTGAGCGGTAAGGCAAACGCTACTATTAAACGTCCAC
TGCCATCTTTCCGATCAGCAACAACAGTAGATGGAAAACCGAAAAATTTAGACGCGAGCATTACGAGTATCATTCATGAA
ATTGGTGTGCCTGCTCATATTAAAGGGTACATGTACTTAAGGGAAGCAATTTCTATGGTGTACAATGACATCGAATTACT
TGGATCTATTACGAAAGTATTGTATCCAGATATCGCGAAGAAATATAATACAACAGCAAGCCGCGTTGAGCGTGCAATCC
GTCACGCAATTGAAGTAGCATGGAGTCGTGGGAATATTGATTCTATTTCGTCCTTATTCGGTTATACAGTATCCATGTCA
AAAGCAAAACCTACGAACTCCGAGTTTATTGCAATGGTTGCGGATAAGCTTAGACTTGAACATAAGGCTAGCTGA

Domains

Predicted by InterproScan.

• Sporulation initiation factor Spo0A C terminal (Spo0A_C) (154-257)

• Response regulator receiver domain (Response_reg) (6-119)

3D structure

• AlphaFold DB: P52928

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
spo0A	Bacillus subtilis subsp. subtilis str. 168	80.899	100	0.818