Detailed information NTG0291446

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: DG474_RS09325
• Genome accession: NZ_CP029257
• Coordinates: 1945214..1947646 (-)
• Length: 810 a.a.
• NCBI ID: WP_255778194.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain CCUG 53468
• Function: degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 1940214..1952646

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DG474_RS09300 (DG474_09455)	-	1941221..1941904 (-)	684	WP_255778191.1	hypothetical protein	-
DG474_RS09305 (DG474_09460)	-	1942170..1942400 (+)	231	WP_049490535.1	hypothetical protein	-
DG474_RS09310 (DG474_09465)	-	1942445..1943218 (-)	774	WP_255778192.1	NUDIX hydrolase	-
DG474_RS09315 (DG474_09470)	pnuC	1943220..1943999 (-)	780	WP_042767588.1	nicotinamide riboside transporter PnuC	-
DG474_RS09320 (DG474_09475)	-	1944009..1945067 (-)	1059	WP_255778193.1	AAA family ATPase	-
DG474_RS09325 (DG474_09480)	clpC	1945214..1947646 (-)	2433	WP_255778194.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
DG474_RS09330 (DG474_09485)	-	1947648..1948106 (-)	459	WP_001211263.1	CtsR family transcriptional regulator	-
DG474_RS09340 (DG474_09490)	-	1948278..1952036 (-)	3759	WP_304665712.1	FctA domain-containing protein	-

Sequence

Protein

• Length: 810 a.a.
• Molecular weight: 90291.07 Da
• Isoelectric Point: 5.8629

>NTDB_id=291446 DG474_RS09325 WP_255778194.1 1945214..1947646(-) (clpC) [Streptococcus oralis strain CCUG 53468]
MNYSKALNECIESAYMVASHFGARYLESWHLLIAMSNHSYSVAGATLNDYPYEMDRLEEVALELTETDYSQDETFTELPF
SHRLEVLFAEAEYVASVVHAKVLGTEHVLYAILHDGNALATRILERAGFSYEDQKDQVRIAALRRNLEERAGWTREDLKA
LRQRHRTVTDKQNSMANMMGMPQAQSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRMIQILSRKTKNNPVLVGDAGVGK
TALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAGTRFRGDFEERMNNIIKDIEEDGKVILFIDELHTIMGSGSGIDST
LDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSLADSITILQGLKATYEKHHRVQITDEAVET
AVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKSKQVKADESDLTPADKALMDGKWKQAAQLIAKEQEVPVYKDLVTESDI
LTTLSRLSGIPVQKLTQTDAKKYLNLEAELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAK
ALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQVLDD
GVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDIRFDQENMEKRIFEELKKAYRPEFINRIDEKVVFHSLDS
EHMQEIVKIMVKPLIASLAEKGIDLKLQASALKLLASQGYDPEMGARPLRRTLQTEVEDKLAELLLKGELVAGKTLKIGV
KAGQLKFDIA

Nucleotide

• Length: 2433 bp

>NTDB_id=291446 DG474_RS09325 WP_255778194.1 1945214..1947646(-) (clpC) [Streptococcus oralis strain CCUG 53468]
ATGAACTATTCAAAAGCATTGAATGAATGTATCGAAAGTGCCTACATGGTTGCGAGCCATTTTGGAGCCCGTTATCTAGA
GTCTTGGCATTTATTGATTGCCATGTCTAATCACAGTTACAGTGTGGCAGGTGCGACTCTAAATGATTACCCATACGAGA
TGGACCGTTTAGAAGAGGTTGCGTTGGAACTGACTGAAACCGACTATAGCCAAGATGAAACCTTTACGGAATTACCCTTT
TCCCATCGTTTGGAGGTCCTCTTTGCGGAAGCAGAGTATGTAGCCTCAGTGGTCCATGCTAAGGTGCTAGGGACAGAGCA
TGTCCTCTATGCGATTTTGCATGACGGCAATGCCTTGGCGACTCGCATCTTGGAGAGAGCAGGTTTCTCTTATGAAGACC
AGAAAGATCAGGTCAGAATTGCTGCTCTTCGTCGCAATCTAGAAGAACGTGCTGGTTGGACAAGAGAAGATCTTAAGGCT
TTGCGTCAACGTCATCGCACAGTAACTGACAAGCAAAATTCCATGGCCAATATGATGGGCATGCCTCAAGCTCAAAGTGG
TGGTCTAGAGGATTACACGCATGATCTGACGGAGCAAGCGCGCTCTGGCAAGTTAGAGCCAGTTATCGGTCGAGACAAGG
AAATCTCACGTATGATTCAGATTTTGAGTCGAAAGACCAAGAACAATCCGGTCTTGGTTGGTGATGCTGGTGTCGGGAAA
ACAGCTCTAGCACTTGGACTTGCCCAGCGTATTGCTAGTGGGGATGTGCCTGCGGAAATGGCAAAGATGCGTGTTCTAGA
GCTTGATTTGATGAATGTTGTTGCGGGGACACGTTTCCGTGGAGATTTTGAAGAGCGCATGAACAATATCATCAAGGATA
TAGAGGAAGATGGCAAAGTGATCCTCTTTATCGATGAACTCCACACCATCATGGGTTCTGGTAGCGGTATTGACTCGACT
CTGGATGCAGCCAATATCTTGAAGCCAGCCTTAGCTCGCGGAACTCTGAGAACAGTTGGTGCAACCACTCAGGAAGAATA
CCAAAAACACATCGAAAAAGACGCAGCCCTTTCTCGTCGTTTCGCCAAAGTAACGATTGAAGAGCCAAGTTTAGCTGACA
GCATAACCATTTTGCAAGGTTTGAAAGCTACCTATGAGAAACATCACCGTGTACAAATTACAGATGAAGCTGTCGAAACA
GCTGTTAAGATGGCGCATCGTTACTTGACCAGTCGTCACTTGCCAGACTCTGCTATCGATCTTTTAGATGAAGCGGCAGC
AACAGTGCAAAACAAATCCAAGCAGGTGAAAGCAGACGAATCCGACTTGACTCCAGCTGACAAGGCCTTGATGGATGGCA
AGTGGAAACAAGCTGCCCAGCTAATCGCAAAGGAGCAGGAAGTCCCTGTCTATAAAGACTTGGTGACAGAATCTGATATT
TTGACCACCTTGAGTCGCTTGTCAGGGATTCCAGTTCAAAAACTGACGCAAACAGATGCTAAGAAATACCTGAACTTGGA
AGCTGAACTACACAAACGTGTCATCGGCCAAGATCAAGCTGTTTCAAGCATTAGCCGTGCCATTCGCCGCAACCAGTCAG
GTATTCGCAGTCACAAGCGTCCGATTGGTTCCTTTATGTTCCTAGGACCGACAGGAGTCGGTAAGACCGAATTGGCAAAG
GCTCTGGCAGAAGTCCTCTTTGATGACGAATCAGCCCTTATCCGCTTTGATATGAGTGAGTATATGGAGAAATTCGCAGC
TAGCCGTCTCAATGGAGCTCCTCCGGGCTATGTAGGCTACGAAGAAGGTGGGGAGTTGACCGAGAAGGTTCGCAACAAAC
CTTACTCCGTTCTCCTCTTTGACGAGGTAGAGAAGGCTCACCCAGATATCTTTAATGTCCTCTTGCAGGTTCTGGACGAC
GGTGTCTTGACAGATAGCAAGGGACGCAAGGTGGACTTTTCAAATACCATTATCATCATGACGTCAAACCTTGGTGCAAC
AGCCCTTCGTGATGACAAGACGGTCGGCTTTGGCGCGAAAGACATTCGTTTTGACCAGGAAAATATGGAAAAACGCATCT
TTGAAGAGTTGAAAAAAGCTTATCGACCAGAGTTTATCAACCGTATTGATGAAAAGGTGGTCTTCCACAGTTTGGATAGC
GAACACATGCAGGAAATTGTCAAGATTATGGTAAAACCATTGATTGCTAGCCTCGCTGAGAAGGGCATCGACTTGAAACT
GCAAGCTTCAGCGTTGAAGTTACTAGCAAGTCAAGGATATGATCCAGAAATGGGAGCTCGCCCACTTCGCAGAACCCTGC
AAACAGAAGTGGAAGACAAGCTAGCAGAACTCCTTCTCAAGGGAGAATTGGTAGCAGGCAAGACCCTCAAGATAGGTGTT
AAAGCTGGTCAATTAAAATTTGATATTGCTTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (540-711)

• AAA lid domain (AAA_lid_9) (371-447)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (718-797)

• ATPase family associated with various cellular activities (AAA) (AAA) (231-362)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (103-133)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (14-49)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Streptococcus pneumoniae TIGR4	96.667	100	0.967
clpC	Streptococcus pneumoniae Rx1	96.667	100	0.967
clpC	Streptococcus pneumoniae D39	96.667	100	0.967
clpC	Streptococcus mutans UA159	67.897	100	0.681
clpC	Streptococcus thermophilus LMD-9	67.322	100	0.677
clpC	Streptococcus thermophilus LMG 18311	67.199	100	0.675
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	49.517	100	0.506
clpC	Bacillus subtilis subsp. subtilis str. 168	45.074	100	0.452
clpE	Streptococcus mutans UA159	49.032	76.543	0.375
clpC	Lactococcus lactis subsp. cremoris KW2	46.73	77.407	0.362