Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   DG474_RS06615 Genome accession   NZ_CP029257
Coordinates   1351355..1353613 (+) Length   752 a.a.
NCBI ID   WP_255777734.1    Uniprot ID   -
Organism   Streptococcus oralis strain CCUG 53468     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1346355..1358613
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DG474_RS06585 (DG474_06690) - 1347139..1347912 (-) 774 WP_255777728.1 HAD hydrolase family protein -
  DG474_RS06590 (DG474_06695) - 1347917..1348774 (-) 858 WP_255777730.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  DG474_RS06595 (DG474_06700) - 1348923..1349243 (-) 321 WP_216728486.1 TfoX/Sxy family protein -
  DG474_RS06600 (DG474_06705) - 1349277..1350011 (-) 735 WP_255777731.1 amino acid ABC transporter ATP-binding protein -
  DG474_RS06605 (DG474_06710) - 1350011..1350694 (-) 684 WP_255777733.1 amino acid ABC transporter permease -
  DG474_RS06610 (DG474_06715) - 1350886..1351116 (+) 231 WP_000443577.1 DUF1797 family protein -
  DG474_RS06615 (DG474_06720) clpE 1351355..1353613 (+) 2259 WP_255777734.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  DG474_RS06620 (DG474_06725) - 1353656..1354270 (-) 615 WP_000873101.1 GyrI-like domain-containing protein -
  DG474_RS06625 (DG474_06730) - 1354325..1355227 (-) 903 WP_255777735.1 YafY family protein -
  DG474_RS06630 (DG474_06735) - 1355414..1355866 (+) 453 WP_255777736.1 NUDIX hydrolase -
  DG474_RS06635 (DG474_06740) - 1355925..1356224 (+) 300 WP_000767208.1 DUF1827 family protein -
  DG474_RS06640 (DG474_06745) metK 1356295..1357485 (-) 1191 WP_044021077.1 methionine adenosyltransferase -

Sequence

Protein


Download         Length: 752 a.a.        Molecular weight: 84040.44 Da        Isoelectric Point: 5.0356

>NTDB_id=291425 DG474_RS06615 WP_255777734.1 1351355..1353613(+) (clpE) [Streptococcus oralis strain CCUG 53468]
MLCQNCKINDSTIHLYTNINGQQKQIDLCQNCYKIIKTDPNNTLFKGMTDLNNRDFDPFGDFFNDLNNFKPSSNNVPPTQ
SGGGYGGNGGYGPQNRGPLQTPPSQERGLLEEYGINVTEIARRGDIDPVIGRDEEIIRVIEILNRRTKNNPVLIGEPGVG
KTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIREREDIILFIDEIHEIVGAGSAGDG
NMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETIIILKGVQKKYEDYHHVKYTDAAIEA
AANLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKAQATREEDFEKAAYFRDQIAKYKEMQKN
KVTDQDTPIISEKTIEHIIEQKTNIPVGELKEKEQSQLIHLADDLKAHVIGQDEAVDKIAKAIRRNRVGLGTPNRPIGSF
LFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRRNPYSLILLDEVEK
AHPDVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKAEASVGFGAAREGRTNSVLGELGNFFSPEFMNRFDGI
IEFKPLSKDNLLQIVELMLADVNKRLSSNNIHLYVTDKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDYYLENPSEK
DLKAVMTNNGKIQIKSAKKTEKTEEITSEIEE

Nucleotide


Download         Length: 2259 bp        

>NTDB_id=291425 DG474_RS06615 WP_255777734.1 1351355..1353613(+) (clpE) [Streptococcus oralis strain CCUG 53468]
ATGCTCTGTCAAAACTGTAAAATTAACGACTCAACAATTCATCTGTATACCAATATCAATGGACAGCAAAAGCAAATTGA
TCTCTGTCAAAATTGCTATAAAATTATCAAAACAGACCCAAACAATACCCTCTTTAAAGGAATGACTGACCTAAACAATC
GTGACTTTGATCCTTTCGGCGACTTTTTCAATGATTTGAACAATTTCAAACCTTCTTCAAATAACGTCCCTCCAACTCAA
TCTGGTGGGGGATATGGAGGAAACGGTGGTTATGGACCTCAAAACCGAGGCCCGCTTCAAACACCTCCTAGCCAAGAAAG
AGGACTCCTAGAGGAATATGGTATCAACGTGACTGAAATAGCTCGTCGAGGAGATATTGACCCTGTTATTGGTCGAGATG
AGGAGATTATCCGCGTTATCGAAATCCTCAACCGTCGAACCAAGAACAATCCTGTCCTTATCGGAGAACCAGGTGTTGGT
AAAACAGCCGTTGTCGAAGGTTTAGCTCAGAAGATTGTCGATGGCGATGTTCCTCATAAACTCCAAGGCAAGCAGGTCAT
CCGTCTGGATGTGGTCAGTCTAGTCCAAGGAACAGGGATTCGAGGCCAATTTGAAGAACGTATGCAAAAACTCATGGAAG
AAATCCGCGAACGCGAGGATATCATTCTCTTTATCGATGAAATCCATGAAATTGTTGGTGCAGGATCTGCTGGCGATGGC
AATATGGATGCAGGAAATATCCTCAAACCTGCTCTTGCCCGTGGTGAATTGCAAATGGTTGGTGCCACTACTCTCAATGA
ATACCGCATCATTGAAAAAGATGCTGCTCTAGAGCGCCGTATGCAGCCTGTCAAGGTAGATGAACCAACTGTCGAAGAAA
CCATTATCATCCTCAAAGGGGTTCAAAAGAAATACGAAGACTACCATCACGTCAAGTATACTGATGCTGCTATCGAAGCT
GCTGCAAATCTTTCCAACCGCTATATCCAAGACCGCTTCTTACCTGACAAGGCTATTGACCTTTTGGACGAAGCCGGTTC
AAAGATGAATCTGACACTGAACTTTGTTGATCCTAAAGTGATTGATCAGCGTTTAATTGAAGCTGAAAATCTCAAGGCGC
AAGCTACACGAGAGGAAGACTTTGAAAAGGCTGCTTATTTCCGCGATCAGATTGCCAAGTACAAAGAAATGCAAAAGAAC
AAGGTGACCGATCAGGATACTCCAATCATCAGCGAAAAAACAATCGAACATATCATTGAGCAAAAAACCAATATCCCTGT
TGGAGAACTCAAAGAAAAAGAACAGTCTCAACTCATCCATCTAGCAGACGACCTCAAAGCTCATGTCATTGGTCAAGATG
AAGCTGTCGATAAGATTGCCAAAGCCATCCGTCGTAATCGTGTTGGACTTGGAACTCCTAACCGGCCAATCGGAAGCTTC
CTCTTTGTCGGACCAACTGGTGTCGGTAAAACAGAACTTTCCAAACAACTAGCCATTGAGCTCTTTGGTTCTGCTGACAG
CATGATTCGCTTTGATATGAGTGAATACATGGAAAAACACAGTGTAGCTAAATTGGTCGGAGCCCCTCCAGGCTATGTAG
GCTATGATGAAGCTGGGCAACTGACTGAAAAAGTTCGTCGCAATCCTTACTCACTCATCCTTCTCGATGAAGTTGAAAAA
GCACACCCAGATGTCATGCACATGTTCCTTCAAGTCTTGGACGATGGTCGTTTGACAGATGGGCAAGGACGTACAGTTAG
CTTTAAGGATGCTATCATTATCATGACCTCAAATGCGGGTACTGGTAAGGCCGAAGCCAGCGTTGGTTTTGGGGCGGCTC
GCGAAGGACGTACCAACTCTGTTCTCGGCGAACTCGGCAACTTCTTTAGTCCGGAGTTTATGAACCGTTTTGACGGCATC
ATCGAATTTAAACCTCTCAGCAAGGACAACCTTCTCCAAATCGTCGAACTCATGCTTGCAGATGTCAACAAACGCCTCTC
TAGCAACAATATCCACCTCTATGTGACAGACAAGGTCAAAGAAAAGTTGGTTGACTTGGGATATGATCCAAAAATGGGGG
CGCGTCCACTCCGCCGTACTATTCAAGACCATATCGAGGATGCCATCACTGACTACTACCTTGAAAATCCAAGTGAAAAA
GACCTCAAGGCAGTTATGACAAACAATGGCAAAATTCAAATCAAATCTGCTAAAAAAACTGAAAAAACAGAAGAGATTAC
TTCTGAAATAGAAGAATAA

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(290-387)

AAA domain (Cdc48 subfamily) (AAA_2)

(475-638)

ATPase family associated with various cellular activities (AAA) (AAA)

(152-271)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(646-720)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

94.489

98.936

0.935
  clpE Streptococcus pneumoniae D39

94.489

98.936

0.935
  clpE Streptococcus pneumoniae R6

94.489

98.936

0.935
  clpE Streptococcus pneumoniae TIGR4

94.355

98.936

0.934
  clpE Streptococcus mutans UA159

83.024

100

0.832
  clpC Lactococcus lactis subsp. cremoris KW2

75.629

100

0.759
  clpC Bacillus subtilis subsp. subtilis str. 168

52.615

86.436

0.455
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

48.485

83.378

0.404
  clpC Streptococcus thermophilus LMD-9

46.91

83.91

0.394
  clpC Streptococcus thermophilus LMG 18311

46.667

83.777

0.391
  clpC Streptococcus pneumoniae TIGR4

47.343

82.58

0.391
  clpC Streptococcus pneumoniae Rx1

47.343

82.58

0.391
  clpC Streptococcus pneumoniae D39

47.343

82.58

0.391
  clpC Streptococcus mutans UA159

46.508

83.777

0.39

Multiple sequence alignment