Detailed information    

insolico Bioinformatically predicted

Overview

Name   endA   Type   Machinery gene
Locus tag   DG474_RS01290 Genome accession   NZ_CP029257
Coordinates   242974..243798 (+) Length   274 a.a.
NCBI ID   WP_084917529.1    Uniprot ID   -
Organism   Streptococcus oralis strain CCUG 53468     
Function   cleavage of dsDNA into ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 237974..248798
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DG474_RS01255 (DG474_01265) asnA 238064..239056 (+) 993 WP_000747998.1 aspartate--ammonia ligase -
  DG474_RS01260 (DG474_01270) rsmD 239121..239660 (+) 540 WP_070656921.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  DG474_RS01265 (DG474_01275) coaD 239650..240138 (+) 489 WP_001280715.1 pantetheine-phosphate adenylyltransferase -
  DG474_RS01270 (DG474_01280) sepM 240122..241159 (+) 1038 WP_049501597.1 SepM family pheromone-processing serine protease Regulator
  DG474_RS01275 (DG474_01285) - 241215..241445 (+) 231 WP_002892633.1 DUF1146 family protein -
  DG474_RS01280 (DG474_01290) murA 241469..242752 (+) 1284 WP_000411918.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  DG474_RS01285 (DG474_01295) - 242739..242933 (+) 195 WP_000739701.1 DNA-directed RNA polymerase subunit beta -
  DG474_RS01290 (DG474_01300) endA 242974..243798 (+) 825 WP_084917529.1 DNA/RNA non-specific endonuclease Machinery gene
  DG474_RS01295 (DG474_01305) - 243934..245265 (+) 1332 WP_255778434.1 hemolysin family protein -
  DG474_RS01305 (DG474_01315) amiA 245768..247747 (+) 1980 WP_255778436.1 peptide ABC transporter substrate-binding protein Regulator

Sequence

Protein


Download         Length: 274 a.a.        Molecular weight: 29983.71 Da        Isoelectric Point: 9.8219

>NTDB_id=291399 DG474_RS01290 WP_084917529.1 242974..243798(+) (endA) [Streptococcus oralis strain CCUG 53468]
MDKKTRQALIGLLLFLLLAAGSYYIKQMQTAPNTPRTKVSQKKQASEAPSQELAESVLTESIKNQIKGGLEWNGAGAFIV
NGNKTNLDAKVSSKPYADNKTKIVGKETVPTVANAILSKATRQYKNREETGNGSTSWTPPGWHQVKNLKGAYTHAVDRGH
LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEDSTGQNYYESLVRKVLDQNKRVRYRVTLHYATNEDLVPSASQIE
AKSSDGELEFNVLIPNVQKGIQLDYRTGQVTVTD

Nucleotide


Download         Length: 825 bp        

>NTDB_id=291399 DG474_RS01290 WP_084917529.1 242974..243798(+) (endA) [Streptococcus oralis strain CCUG 53468]
ATGGACAAAAAAACAAGACAAGCTCTGATAGGGTTACTTCTATTCTTACTCTTGGCTGCTGGAAGCTATTACATCAAGCA
GATGCAGACAGCGCCAAACACCCCTAGAACCAAGGTTAGTCAGAAAAAACAAGCTTCAGAAGCTCCCAGTCAGGAGCTTG
CTGAAAGTGTCTTAACTGAGTCAATCAAAAACCAAATCAAGGGGGGGCTCGAGTGGAATGGAGCAGGGGCCTTCATTGTC
AATGGCAATAAAACCAATCTAGATGCCAAGGTTTCTAGCAAACCCTATGCGGATAATAAGACAAAGATAGTTGGAAAAGA
AACAGTTCCAACTGTTGCCAATGCCATCTTATCCAAAGCGACTCGGCAGTATAAAAATCGTGAAGAAACTGGAAATGGAT
CCACCTCTTGGACGCCACCAGGATGGCATCAGGTCAAGAATCTAAAGGGAGCCTACACACATGCAGTTGATAGAGGACAC
CTGCTGGGCTATGCCTTGATAGGTGGTTTGGATGGTTTTGATGCCTCTACTAGCAATCCCAAGAACATTGCAGTCCAGAC
AGCTTGGGCAAACCAAGCACAGGCTGAAGATTCGACAGGTCAGAACTACTATGAGAGTTTGGTCAGAAAAGTCTTGGACC
AAAATAAGAGAGTCCGTTATCGGGTGACGCTCCACTATGCGACAAATGAGGACTTAGTTCCATCCGCTTCACAAATCGAA
GCCAAGTCTTCAGATGGCGAATTGGAATTCAATGTCCTAATCCCCAATGTTCAAAAGGGAATCCAGCTTGATTACCGAAC
AGGGCAAGTAACAGTGACAGATTAG

Domains

Predicted by InterproScan.

DNA/RNA non-specific endonuclease (Endonuclease_NS)

(76-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  endA Streptococcus pneumoniae Rx1

88.645

99.635

0.883
  endA Streptococcus pneumoniae D39

88.645

99.635

0.883
  endA Streptococcus pneumoniae R6

88.645

99.635

0.883
  endA Streptococcus pneumoniae TIGR4

88.645

99.635

0.883

Multiple sequence alignment