Detailed information NTG0290897

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: DD555_RS14935
• Genome accession: NZ_CP029166
• Coordinates: 2812304..2813191 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain SVH7513
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2807304..2818191

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DD555_RS14900 (DD555_14895)	-	2807323..2807415 (+)	93	WP_010956583.1	hypothetical protein	-
DD555_RS14905 (DD555_14900)	-	2807523..2808020 (-)	498	WP_001065268.1	glutathione peroxidase	-
DD555_RS14910 (DD555_14905)	-	2808030..2808290 (-)	261	WP_001789910.1	hypothetical protein	-
DD555_RS14920 (DD555_14915)	-	2808672..2808785 (-)	114	WP_011447078.1	hypothetical protein	-
DD555_RS14925 (DD555_14920)	-	2809444..2811444 (-)	2001	WP_000776751.1	ABC transporter permease	-
DD555_RS14930 (DD555_14925)	-	2811441..2812196 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
DD555_RS14935 (DD555_14930)	braS	2812304..2813191 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
DD555_RS14940 (DD555_14935)	braR	2813202..2813867 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
DD555_RS14945 (DD555_14940)	-	2813893..2814093 (-)	201	WP_000604728.1	hypothetical protein	-
DD555_RS14950 (DD555_14945)	-	2814291..2815715 (+)	1425	WP_000953744.1	alkaline phosphatase	-
DD555_RS15850 (DD555_14950)	-	2815775..2815876 (-)	102	WP_000731972.1	SE2200 family small protein	-
DD555_RS14960 (DD555_14955)	-	2815998..2816453 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
DD555_RS14965 (DD555_14960)	-	2816698..2817459 (-)	762	WP_000323455.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=290897 DD555_RS14935 WP_000143419.1 2812304..2813191(-) (braS) [Staphylococcus aureus strain SVH7513]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=290897 DD555_RS14935 WP_000143419.1 2812304..2813191(-) (braS) [Staphylococcus aureus strain SVH7513]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997