Detailed information NTG0290320

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: CSC47_RS10830
• Genome accession: NZ_CP029087
• Coordinates: 2072828..2073871 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain AR461
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2067828..2078871

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CSC47_RS10800 (CSC47_1865)	-	2068249..2069505 (-)	1257	WP_001795108.1	aminopeptidase	-
CSC47_RS10805 (CSC47_1866)	-	2069508..2069708 (-)	201	WP_000180460.1	DUF1128 family protein	-
CSC47_RS10810 (CSC47_1867)	-	2069855..2070319 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
CSC47_RS10815 (CSC47_1868)	-	2070326..2070601 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
CSC47_RS10820 (CSC47_1869)	-	2070879..2072096 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
CSC47_RS10825 (CSC47_1870)	vraR	2072209..2072838 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
CSC47_RS10830 (CSC47_1871)	vraS	2072828..2073871 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
CSC47_RS10835 (CSC47_1872)	liaF	2073868..2074569 (-)	702	WP_108711071.1	cell wall-active antibiotics response protein LiaF	-
CSC47_RS10840 (CSC47_1873)	-	2074584..2074970 (-)	387	WP_001110179.1	hypothetical protein	-
CSC47_RS10845 (CSC47_1874)	map	2075187..2075945 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
CSC47_RS10850 (CSC47_1875)	-	2076417..2077403 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
CSC47_RS10860 (CSC47_1876)	-	2077834..2078247 (-)	414	WP_001557448.1	hypothetical protein	-
CSC47_RS10865	-	2078276..2078386 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=290320 CSC47_RS10830 WP_001017131.1 2072828..2073871(-) (vraS) [Staphylococcus aureus strain AR461]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=290320 CSC47_RS10830 WP_001017131.1 2072828..2073871(-) (vraS) [Staphylococcus aureus strain AR461]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1