Detailed information NTG0290279

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: CSC48_RS11930
• Genome accession: NZ_CP029086
• Coordinates: 2282580..2283566 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain AR462
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 2277580..2288566

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CSC48_RS11905 (CSC48_2145)	opp4B	2277794..2278756 (+)	963	WP_000915997.1	oligopeptide ABC transporter permease	-
CSC48_RS11910 (CSC48_2146)	opp4C	2278768..2279649 (+)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
CSC48_RS11915 (CSC48_2147)	trpS	2279691..2280680 (-)	990	WP_000448934.1	tryptophan--tRNA ligase	-
CSC48_RS11920 (CSC48_2148)	spxA	2280974..2281369 (+)	396	WP_000258003.1	transcriptional regulator SpxA	-
CSC48_RS11925 (CSC48_2149)	mecA	2281740..2282459 (+)	720	WP_001217728.1	adaptor protein MecA	-
CSC48_RS11930 (CSC48_2150)	coiA	2282580..2283566 (+)	987	WP_000959282.1	competence protein CoiA family protein	Machinery gene
CSC48_RS11935 (CSC48_2151)	pepF	2283614..2285422 (+)	1809	WP_000082725.1	oligoendopeptidase F	-
CSC48_RS11940 (CSC48_2152)	yjbH	2285882..2286688 (-)	807	WP_000896697.1	protease adaptor protein YjbH	-
CSC48_RS11945 (CSC48_2153)	-	2286711..2287076 (-)	366	WP_000214070.1	truncated hemoglobin YjbI	-
CSC48_RS11950 (CSC48_2154)	-	2287180..2287773 (-)	594	WP_000224619.1	CYTH domain-containing protein	-
CSC48_RS11955 (CSC48_2155)	-	2287959..2288306 (+)	348	WP_001242103.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=290279 CSC48_RS11930 WP_000959282.1 2282580..2283566(+) (coiA) [Staphylococcus aureus strain AR462]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=290279 CSC48_RS11930 WP_000959282.1 2282580..2283566(+) (coiA) [Staphylococcus aureus strain AR462]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976