Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   CSC51_RS10460 Genome accession   NZ_CP029080
Coordinates   2066963..2067937 (-) Length   324 a.a.
NCBI ID   WP_000697223.1    Uniprot ID   -
Organism   Staphylococcus aureus strain AR466     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2061963..2072937
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CSC51_RS10420 (CSC51_1919) gcvT 2062464..2063555 (-) 1092 WP_000093344.1 glycine cleavage system aminomethyltransferase GcvT -
  CSC51_RS10425 (CSC51_1920) - 2063714..2064238 (-) 525 WP_001015120.1 shikimate kinase -
  CSC51_RS10430 - 2064228..2064374 (-) 147 WP_001789879.1 hypothetical protein -
  CSC51_RS10435 (CSC51_1921) comGF 2064471..2064968 (-) 498 WP_001796472.1 competence type IV pilus minor pilin ComGF Machinery gene
  CSC51_RS10440 (CSC51_1922) comGE 2064886..2065185 (-) 300 WP_000844413.1 hypothetical protein Machinery gene
  CSC51_RS10445 (CSC51_1923) comGD 2065172..2065618 (-) 447 WP_001796473.1 competence type IV pilus minor pilin ComGD Machinery gene
  CSC51_RS10450 (CSC51_1924) comGC 2065596..2065907 (-) 312 WP_000472255.1 competence type IV pilus major pilin ComGC Machinery gene
  CSC51_RS10455 (CSC51_1925) comGB 2065921..2066991 (-) 1071 WP_000776409.1 competence type IV pilus assembly protein ComGB Machinery gene
  CSC51_RS10460 (CSC51_1926) comGA 2066963..2067937 (-) 975 WP_000697223.1 competence type IV pilus ATPase ComGA Machinery gene
  CSC51_RS10465 (CSC51_1927) - 2067989..2068612 (-) 624 WP_001223009.1 MBL fold metallo-hydrolase -
  CSC51_RS10470 (CSC51_1928) - 2068609..2068938 (-) 330 WP_001018871.1 MTH1187 family thiamine-binding protein -
  CSC51_RS10475 (CSC51_1929) - 2068938..2069924 (-) 987 WP_000161307.1 ROK family glucokinase -
  CSC51_RS10480 (CSC51_1930) - 2069921..2070124 (-) 204 WP_000087561.1 YqgQ family protein -
  CSC51_RS10485 (CSC51_1931) - 2070105..2071568 (-) 1464 WP_001017870.1 rhomboid family intramembrane serine protease -
  CSC51_RS10490 (CSC51_1932) - 2071580..2072119 (-) 540 WP_000164546.1 5-formyltetrahydrofolate cyclo-ligase -
  CSC51_RS10495 (CSC51_1933) rpmG 2072328..2072477 (-) 150 WP_001265709.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36926.01 Da        Isoelectric Point: 8.8516

>NTDB_id=290136 CSC51_RS10460 WP_000697223.1 2066963..2067937(-) (comGA) [Staphylococcus aureus strain AR466]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIVPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQVTNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=290136 CSC51_RS10460 WP_000697223.1 2066963..2067937(-) (comGA) [Staphylococcus aureus strain AR466]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGACTTGATGTATCTACACAACAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTGATCAGAATTGTACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGACCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATTGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTTGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGTAACTAACTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

99.691

100

0.997
  comGA Staphylococcus aureus N315

99.691

100

0.997

Multiple sequence alignment