Detailed information NTG0290085

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: EJ992_RS00610
• Genome accession: NZ_CP034569
• Coordinates: 111824..112900 (+)
• Length: 358 a.a.
• NCBI ID: WP_003178277.1
• Uniprot ID: Q65PD4
• Organism: Bacillus licheniformis strain ATCC 14580
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 106824..117900

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EJ992_RS00595 (EJ992_00595)	-	106841..107932 (+)	1092	WP_003178273.1	protein arginine kinase	-
EJ992_RS00600 (EJ992_00600)	clpC	107929..110361 (+)	2433	WP_003178275.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
EJ992_RS00605 (EJ992_00605)	radA/sms	110441..111820 (+)	1380	WP_003178276.1	DNA repair protein RadA	Machinery gene
EJ992_RS00610 (EJ992_00610)	disA	111824..112900 (+)	1077	WP_003178277.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
EJ992_RS00615 (EJ992_00615)	-	113032..114120 (+)	1089	WP_009330350.1	PIN/TRAM domain-containing protein	-
EJ992_RS00620 (EJ992_00620)	ispD	114137..114832 (+)	696	WP_009330349.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
EJ992_RS00625 (EJ992_00625)	ispF	114825..115301 (+)	477	WP_003178280.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
EJ992_RS00630 (EJ992_00630)	gltX	115383..116840 (+)	1458	WP_009330348.1	glutamate--tRNA ligase	-
EJ992_RS00635 (EJ992_00635)	cysE	117142..117792 (+)	651	WP_003178282.1	serine O-acetyltransferase	-

Sequence

Protein

• Length: 358 a.a.
• Molecular weight: 40582.27 Da
• Isoelectric Point: 6.5986

>NTDB_id=290085 EJ992_RS00610 WP_003178277.1 111824..112900(+) (disA) [Bacillus licheniformis strain ATCC 14580]
MDKDKKGAKQDLSEILQFVAPGTPLREGIENVLRAKTGGLIVVGFNDKVKEVVDGGFHINSSFSPAHLYELAKMDGAIIL
SDSGQKILYANTQLMPEATIPSSETGMRHRTAERVAKQTGCLIIAISERRNVITLYQENMKYILKDIGFILTKANQAIQT
LEKYKLILDHAISNLNALEFEELVTFGDVISVLHRYEMVLRIKNEINMYIKELGTEGHLIRLQVSELITDMEQEAALFVK
DYVKEKIKDPFVLLKQLQDMSSFELLDDAILLKLLGYSATTNMEEYVFPRGYRLLHKIPRLPMPIVENVVEAFGHLKLII
EADVKDLDEVEGIGAVRAQKIKKGLKRLQEKHYTDRQL

Nucleotide

• Length: 1077 bp

>NTDB_id=290085 EJ992_RS00610 WP_003178277.1 111824..112900(+) (disA) [Bacillus licheniformis strain ATCC 14580]
ATGGACAAAGACAAAAAAGGAGCGAAACAGGATCTTTCAGAAATATTGCAGTTTGTCGCCCCCGGCACGCCTCTTCGCGA
AGGAATCGAAAACGTCCTTCGGGCCAAAACAGGCGGATTAATCGTGGTCGGCTTCAACGATAAAGTGAAAGAAGTGGTTG
ACGGAGGGTTCCACATAAATTCTTCTTTCTCTCCGGCTCATCTGTACGAGCTGGCTAAAATGGACGGGGCGATCATTCTC
AGCGATTCAGGGCAAAAAATTCTATATGCCAATACACAGCTCATGCCTGAGGCGACGATTCCCTCCTCTGAGACGGGCAT
GAGACACAGAACAGCCGAGCGTGTGGCCAAGCAGACCGGCTGTCTGATCATCGCGATTTCTGAAAGACGGAATGTGATTA
CGCTCTATCAGGAAAATATGAAATATATACTCAAAGATATCGGCTTTATCTTAACAAAAGCCAATCAGGCGATTCAGACG
CTCGAAAAATACAAACTCATTTTGGACCATGCGATTTCCAATTTGAACGCGCTGGAATTTGAAGAGCTTGTTACATTTGG
GGATGTCATCTCCGTTCTGCATCGATATGAAATGGTGCTCAGAATCAAAAACGAAATTAATATGTATATTAAAGAGCTTG
GAACAGAAGGCCATCTCATCAGACTCCAGGTTAGCGAACTGATCACCGATATGGAGCAGGAAGCGGCGCTGTTCGTCAAA
GATTATGTGAAAGAAAAAATCAAAGACCCGTTTGTTCTGCTGAAACAGCTTCAGGATATGTCGAGTTTCGAATTGCTGGA
TGATGCGATTCTCCTTAAGCTTTTAGGCTATTCAGCAACTACGAACATGGAAGAATACGTTTTTCCGAGAGGCTACAGGC
TTCTCCACAAAATTCCCCGCCTCCCGATGCCGATCGTCGAAAATGTTGTCGAAGCATTCGGCCATTTAAAGCTCATTATC
GAAGCGGATGTAAAAGATTTGGATGAAGTGGAAGGAATTGGGGCTGTTCGTGCCCAAAAGATAAAGAAAGGGTTAAAGAG
ACTTCAGGAGAAACATTATACTGACAGGCAGCTGTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (27-139)

• DisA bacterial checkpoint controller linker region (DisA-linker) (144-282)

3D structure

• AlphaFold DB: Q65PD4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	86.111	100	0.866