Detailed information NTG0028999

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SAHV_RS10180
• Genome accession: NC_009782
• Coordinates: 2026553..2027596 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017146.1
• Uniprot ID: Q7A2Q0
• Organism: Staphylococcus aureus subsp. aureus Mu3
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2021553..2032596

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAHV_RS10150 (SAHV_1864)	-	2021974..2023230 (-)	1257	WP_001795108.1	aminopeptidase	-
SAHV_RS10155 (SAHV_1865)	-	2023233..2023433 (-)	201	WP_000180460.1	DUF1128 family protein	-
SAHV_RS10160 (SAHV_1866)	-	2023580..2024044 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
SAHV_RS10165 (SAHV_1867)	-	2024051..2024326 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
SAHV_RS10170 (SAHV_1868)	-	2024604..2025821 (+)	1218	WP_000037068.1	YihY/virulence factor BrkB family protein	-
SAHV_RS10175 (SAHV_1869)	vraR	2025934..2026563 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
SAHV_RS10180 (SAHV_1870)	vraS	2026553..2027596 (-)	1044	WP_001017146.1	sensor histidine kinase	Regulator
SAHV_RS10185 (SAHV_1871)	liaF	2027593..2028294 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
SAHV_RS10190 (SAHV_1872)	-	2028309..2028695 (-)	387	WP_001110179.1	hypothetical protein	-
SAHV_RS10195 (SAHV_1873)	map	2028912..2029670 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
SAHV_RS10205 (SAHV_1874)	-	2030201..2031187 (+)	987	WP_000999717.1	FUSC family protein	-
SAHV_RS10210 (SAHV_1875)	-	2031618..2032031 (-)	414	WP_001557448.1	hypothetical protein	-
SAHV_RS10215	-	2032060..2032170 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40045.46 Da
• Isoelectric Point: 6.0577

>NTDB_id=28999 SAHV_RS10180 WP_001017146.1 2026553..2027596(-) (vraS) [Staphylococcus aureus subsp. aureus Mu3]
MNHYNRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=28999 SAHV_RS10180 WP_001017146.1 2026553..2027596(-) (vraS) [Staphylococcus aureus subsp. aureus Mu3]
ATGAACCACTACAATAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• PDB: 4GT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	99.712	100	0.997