Detailed information
Bioinformatically predicted
Overview
| Name | ccrB | Type | Machinery gene |
| Locus tag | SAHV_RS00290 | Genome accession | NC_009782 |
| Coordinates | 63358..64986 (-) | Length | 542 a.a. |
| NCBI ID | WP_001186602.1 | Uniprot ID | Q9XB94 |
| Organism | Staphylococcus aureus subsp. aureus Mu3 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 58137..101862 | 63358..64986 | within | 0 |
| SCCmec | 44992..66357 | 63358..64986 | within | 0 |
Gene organization within MGE regions
Location: 44992..101862
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| SAHV_RS00195 (SAHV_0040) | mecA | 44992..47001 (-) | 2010 | WP_001801873.1 | PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA | - |
| SAHV_RS00200 (SAHV_0041) | mecR1 | 47098..48855 (+) | 1758 | WP_000952923.1 | beta-lactam sensor/signal transducer MecR1 | - |
| SAHV_RS00205 (SAHV_0042) | mecI | 48855..49226 (+) | 372 | WP_000369211.1 | mecA-type methicillin resistance repressor MecI | - |
| SAHV_RS15370 | psm-mec | 49311..49379 (-) | 69 | WP_014532405.1 | phenol-soluble modulin PSM-mec | - |
| SAHV_RS00210 (SAHV_0043) | - | 49713..50843 (+) | 1131 | WP_010924741.1 | ROK family transcriptional regulator | - |
| SAHV_RS00220 (SAHV_0045) | cstB | 50957..52291 (-) | 1335 | Protein_40 | persulfide dioxygenase-sulfurtransferase CstB | - |
| SAHV_RS00225 (SAHV_0046) | - | 52324..53388 (-) | 1065 | WP_000438836.1 | DsrE/DsrF/DrsH-like family protein | - |
| SAHV_RS00230 (SAHV_0047) | cstR | 53524..53784 (+) | 261 | WP_000220507.1 | persulfide-sensing transcriptional repressor CstR | - |
| SAHV_RS00235 (SAHV_0048) | - | 53784..54422 (+) | 639 | Protein_43 | sulfite exporter TauE/SafE family protein | - |
| SAHV_RS15840 | - | 54476..54535 (-) | 60 | Protein_44 | DNA repair protein RadC | - |
| SAHV_RS00240 (SAHV_0049) | - | 54767..55429 (-) | 663 | WP_001092058.1 | class I SAM-dependent methyltransferase | - |
| SAHV_RS15845 | - | 55821..55880 (+) | 60 | WP_010959190.1 | erythromycin resistance leader peptide | - |
| SAHV_RS00245 (SAHV_0051) | erm(A) | 55963..56694 (+) | 732 | WP_001072201.1 | 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(A) | - |
| SAHV_RS00250 (SAHV_0052) | - | 56820..57602 (-) | 783 | WP_000067268.1 | aminoglycoside nucleotidyltransferase ANT(9)-Ia | - |
| SAHV_RS00255 (SAHV_0053) | - | 57753..58130 (-) | 378 | WP_000361059.1 | DUF6262 family protein | - |
| SAHV_RS00260 (SAHV_0054) | - | 58137..60029 (-) | 1893 | WP_001557544.1 | site-specific integrase | - |
| SAHV_RS00265 (SAHV_0055) | - | 60026..61111 (-) | 1086 | WP_000868132.1 | tyrosine-type recombinase/integrase | - |
| SAHV_RS00270 (SAHV_0056) | - | 61230..61547 (-) | 318 | WP_000659050.1 | JAB domain-containing protein | - |
| SAHV_RS00275 (SAHV_0057) | - | 61568..62074 (-) | 507 | WP_001092169.1 | DUF1643 domain-containing protein | - |
| SAHV_RS00280 (SAHV_0058) | - | 62092..62403 (-) | 312 | WP_000700853.1 | DUF960 family protein | - |
| SAHV_RS00285 (SAHV_0059) | - | 62490..62840 (-) | 351 | WP_000859153.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| SAHV_RS00290 (SAHV_0060) | ccrB | 63358..64986 (-) | 1629 | WP_001186602.1 | cassette chromosome recombinase CcrB | Machinery gene |
| SAHV_RS00295 (SAHV_0061) | ccrA | 65008..66357 (-) | 1350 | WP_000815646.1 | cassette chromosome recombinase CcrA | Machinery gene |
| SAHV_RS00300 (SAHV_0062) | cch1 | 66591..68384 (-) | 1794 | WP_000195100.1 | cassette chromosome replicative helicase | - |
| SAHV_RS00305 (SAHV_0063) | ssb | 68384..68680 (-) | 297 | WP_000273824.1 | cassette chromosome ssDNA-binding protein | - |
| SAHV_RS00310 (SAHV_0064) | - | 68873..69919 (-) | 1047 | WP_001060127.1 | hypothetical protein | - |
| SAHV_RS14750 | - | 70170..71311 (-) | 1142 | Protein_61 | IS3-like element ISSau4 family transposase | - |
| SAHV_RS15775 | - | 71481..71615 (+) | 135 | WP_001792216.1 | hypothetical protein | - |
| SAHV_RS00325 | - | 71822..72757 (-) | 936 | Protein_63 | YfcC family protein | - |
| SAHV_RS00330 (SAHV_0069) | - | 73470..74165 (-) | 696 | WP_000858967.1 | response regulator transcription factor | - |
| SAHV_RS00335 (SAHV_0070) | - | 74140..76794 (-) | 2655 | Protein_65 | ATP-binding protein | - |
| SAHV_RS00340 | kdpF | 76976..77056 (+) | 81 | WP_000631574.1 | K(+)-transporting ATPase subunit F | - |
| SAHV_RS00345 (SAHV_0071) | kdpA | 77077..78753 (+) | 1677 | WP_000029430.1 | potassium-transporting ATPase subunit KdpA | - |
| SAHV_RS00350 (SAHV_0072) | - | 78772..80793 (+) | 2022 | WP_000852430.1 | K(+)-transporting ATPase subunit B | - |
| SAHV_RS00355 (SAHV_0073) | - | 80809..81366 (+) | 558 | WP_001193482.1 | K(+)-transporting ATPase subunit C | - |
| SAHV_RS00360 (SAHV_0074) | - | 81911..82780 (-) | 870 | WP_000626133.1 | hypothetical protein | - |
| SAHV_RS00365 (SAHV_0075) | - | 82790..83686 (-) | 897 | WP_000411461.1 | DUF927 domain-containing protein | - |
| SAHV_RS00375 (SAHV_0079) | - | 84805..85431 (-) | 627 | WP_001176969.1 | hypothetical protein | - |
| SAHV_RS00380 (SAHV_0080) | - | 85546..87054 (+) | 1509 | WP_001001347.1 | protein kinase domain-containing protein | - |
| SAHV_RS00385 | - | 87304..87438 (-) | 135 | WP_001790628.1 | hypothetical protein | - |
| SAHV_RS00390 | - | 87402..87494 (+) | 93 | WP_001790000.1 | hypothetical protein | - |
| SAHV_RS00395 (SAHV_0081) | - | 87641..89386 (+) | 1746 | WP_000700190.1 | DUF6119 family protein | - |
| SAHV_RS00400 (SAHV_0082) | - | 89484..89839 (-) | 356 | Protein_77 | tRNA-dihydrouridine synthase | - |
| SAHV_RS00405 | - | 90144..90232 (-) | 89 | Protein_78 | hypothetical protein | - |
| SAHV_RS00410 (SAHV_0083) | - | 90330..91085 (-) | 756 | WP_000355845.1 | sulfite exporter TauE/SafE family protein | - |
| SAHV_RS00415 (SAHV_0084) | cstR | 91085..91345 (-) | 261 | WP_001105088.1 | persulfide-sensing transcriptional repressor CstR | - |
| SAHV_RS00420 (SAHV_0085) | cstA | 91482..92546 (+) | 1065 | WP_000816124.1 | persulfide response sulfurtransferase CstA | - |
| SAHV_RS00425 (SAHV_0086) | cstB | 92577..93911 (+) | 1335 | WP_000465472.1 | persulfide dioxygenase-sulfurtransferase CstB | - |
| SAHV_RS00430 (SAHV_0087) | sqr | 93930..95123 (+) | 1194 | WP_001033018.1 | type II sulfide:quinone oxidoreductase Sqr | - |
| SAHV_RS15820 | - | 95390..95604 (-) | 215 | Protein_84 | universal stress protein | - |
| SAHV_RS00440 (SAHV_0088) | - | 95790..96776 (-) | 987 | WP_000662022.1 | tRNA dihydrouridine synthase | - |
| SAHV_RS00445 (SAHV_0089) | - | 97085..97288 (+) | 204 | WP_000389759.1 | DUF6007 family protein | - |
| SAHV_RS00450 (SAHV_0090) | - | 97337..97633 (+) | 297 | WP_000201644.1 | TfoX/Sxy family protein | - |
| SAHV_RS00455 (SAHV_0091) | - | 97841..98443 (+) | 603 | WP_000908956.1 | hypothetical protein | - |
| SAHV_RS00460 (SAHV_0092) | - | 98710..101862 (+) | 3153 | WP_000080564.1 | DEAD/DEAH box helicase | - |
Sequence
Protein
Download Length: 542 a.a. Molecular weight: 62664.84 Da Isoelectric Point: 9.8600
>NTDB_id=28964 SAHV_RS00290 WP_001186602.1 63358..64986(-) (ccrB) [Staphylococcus aureus subsp. aureus Mu3]
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
MQQLKTKRVGIYVRVSTEMQSTEGYSIDGQINQIKEYCDFHHFEVKDIYADRGISGKSMNRPELQRILKDAKEGYIDCVM
VYKTNRLARNTSDLLKIVEDLHKQNVEFFSLSERMEVNTSSGKLMLQILASFSEFERNNIVENVFMGQTRRAQEGYYQGN
LPLGYDKIPNSKHELMINQHEANIVKYIFESYAKGHGYRKIANALNHKGYVTKKGKPFSISSITYILANPFYIGKIQFAK
YKDWSEKRRKGLNDKPVIAEGKHSPIINQDLWDKVQMRKKQVSQKPQVHGKGTNLLTGIIHCPQCGAPMAASNTTNTLKD
GTKKRIRYYSCSNFRNKGSKVCSANSVRADVIEDYVMKQILEIVKSDKVIQRVVTHVNQENQVDGAALHHDIAYKQQQYD
EVQIKLNNLIKTIEDNPDLTSVIRPSIQKYEKQLNDITNQINQLKNQQNEDKPLFDAKEISKLLQHIFHDIKHIEKSRLK
ALYLSVIDRIDIKKDGNHKKQFYVTLKLNNEIIKQLFNNKQLDEVHLSTSSLFLPQTLYLTI
Nucleotide
Download Length: 1629 bp
>NTDB_id=28964 SAHV_RS00290 WP_001186602.1 63358..64986(-) (ccrB) [Staphylococcus aureus subsp. aureus Mu3]
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
ATGCAACAACTTAAAACAAAACGTGTCGGTATCTATGTACGTGTATCAACAGAAATGCAAAGCACAGAAGGTTATAGTAT
CGACGGACAAATCAATCAAATCAAAGAATACTGTGACTTCCATCATTTTGAAGTTAAAGATATATACGCTGACCGTGGTA
TTTCAGGTAAATCTATGAATCGACCTGAGCTCCAACGTATATTGAAGGATGCGAAAGAAGGCTATATCGACTGTGTTATG
GTCTACAAAACAAACCGATTAGCTCGTAATACATCTGATCTTCTCAAAATTGTCGAAGATTTACACAAACAAAATGTCGA
ATTTTTCAGTTTATCAGAGCGTATGGAAGTCAATACTTCATCGGGTAAGCTCATGTTACAAATACTTGCGAGTTTCTCAG
AATTCGAACGTAATAACATTGTCGAGAATGTATTTATGGGTCAAACGAGACGTGCCCAAGAAGGCTATTATCAAGGCAAT
TTGCCGCTGGGCTATGACAAAATACCTAATAGTAAACATGAACTGATGATTAATCAACATGAAGCTAATATTGTGAAATA
TATATTCGAGTCCTATGCCAAAGGCCATGGCTATCGTAAAATAGCCAATGCATTAAATCACAAAGGCTATGTCACTAAAA
AGGGTAAACCTTTTAGTATTAGTTCTATCACATATATATTAGCTAACCCATTCTATATCGGCAAAATTCAATTTGCGAAA
TACAAAGATTGGAGTGAAAAACGTCGTAAAGGGCTTAATGATAAACCAGTGATAGCTGAAGGTAAGCATTCCCCCATTAT
TAATCAAGATTTATGGGATAAAGTACAAATGCGTAAAAAACAAGTCAGTCAAAAACCCCAAGTCCATGGCAAAGGAACGA
ATCTGCTTACAGGCATTATTCACTGTCCCCAATGTGGCGCACCTATGGCAGCAAGCAATACCACGAATACACTTAAAGAC
GGGACTAAGAAACGTATTCGTTACTATTCATGTAGTAATTTTCGGAACAAGGGTTCCAAAGTATGTTCGGCAAACAGTGT
AAGAGCTGATGTGATTGAAGATTATGTGATGAAGCAAATACTTGAAATAGTCAAAAGTGATAAAGTCATTCAACGCGTAG
TAACACACGTCAATCAAGAAAATCAAGTTGATGGCGCTGCACTTCATCACGATATTGCTTATAAGCAACAACAATATGAT
GAAGTACAAATCAAACTAAATAACTTGATTAAAACCATCGAGGATAATCCGGACTTAACATCAGTAATCAGACCAAGTAT
TCAAAAATATGAAAAGCAACTCAATGACATTACGAATCAAATCAACCAACTCAAAAATCAACAAAATGAAGATAAGCCTT
TATTTGATGCCAAAGAAATCAGTAAACTATTACAACACATCTTTCATGATATTAAGCACATAGAAAAATCTCGACTCAAA
GCATTGTATCTATCAGTGATTGATCGCATTGATATTAAAAAAGATGGTAATCATAAAAAACAATTCTATGTCACACTCAA
ACTTAATAACGAAATCATAAAACAACTTTTCAATAATAAACAACTCGACGAAGTGCATCTCAGCACTTCGTCTTTGTTTT
TGCCCCAAACACTATATCTTACTATTTAG
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrB | Staphylococcus aureus N315 |
100 |
100 |
1 |