Detailed information NTG0289221

Bioinformatically predicted

Overview

• Name: sxy/tfoX
• Type: Regulator
• Locus tag: APPSER1_RS09615
• Genome accession: NZ_CP029003
• Coordinates: 2037293..2037949 (-)
• Length: 218 a.a.
• NCBI ID: WP_005609196.1
• Uniprot ID: A3N356
• Organism: Actinobacillus pleuropneumoniae serovar 1 str. 4074
• Function: positive regulator of competence gene (predicted from homology) Competence regulation

Genomic Context

Location: 2032293..2042949

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
APPSER1_RS09595 (APPSER1_09595)	nanA	2032667..2033545 (+)	879	WP_005599265.1	N-acetylneuraminate lyase	-
APPSER1_RS09600 (APPSER1_09600)	nagB	2033595..2034398 (+)	804	WP_005599267.1	glucosamine-6-phosphate deaminase	-
APPSER1_RS09605 (APPSER1_09605)	nagA	2034450..2035595 (+)	1146	WP_005599269.1	N-acetylglucosamine-6-phosphate deacetylase	-
APPSER1_RS09610 (APPSER1_09610)	fumC	2035744..2037138 (-)	1395	WP_005599273.1	class II fumarate hydratase	-
APPSER1_RS09615 (APPSER1_09615)	sxy/tfoX	2037293..2037949 (-)	657	WP_005609196.1	TfoX/Sxy family DNA transformation protein	Regulator
APPSER1_RS09620 (APPSER1_09620)	rpsJ	2038357..2038668 (+)	312	WP_001181005.1	30S ribosomal protein S10	-
APPSER1_RS09625 (APPSER1_09625)	rplC	2038694..2039320 (+)	627	WP_005599280.1	50S ribosomal protein L3	-
APPSER1_RS09630 (APPSER1_09630)	rplD	2039336..2039938 (+)	603	WP_005599282.1	50S ribosomal protein L4	-
APPSER1_RS09635 (APPSER1_09635)	rplW	2039935..2040240 (+)	306	WP_005599290.1	50S ribosomal protein L23	-
APPSER1_RS09640 (APPSER1_09640)	rplB	2040261..2041082 (+)	822	WP_005599291.1	50S ribosomal protein L2	-
APPSER1_RS09645 (APPSER1_09645)	rpsS	2041110..2041385 (+)	276	WP_005539416.1	30S ribosomal protein S19	-
APPSER1_RS09650 (APPSER1_09650)	rplV	2041396..2041728 (+)	333	WP_005599292.1	50S ribosomal protein L22	-
APPSER1_RS09655 (APPSER1_09655)	rpsC	2041747..2042454 (+)	708	WP_005599293.1	30S ribosomal protein S3	-
APPSER1_RS09660 (APPSER1_09660)	rplP	2042468..2042878 (+)	411	WP_005599294.1	50S ribosomal protein L16	-

Sequence

Protein

• Length: 218 a.a.
• Molecular weight: 25633.15 Da
• Isoelectric Point: 9.9359

>NTDB_id=289221 APPSER1_RS09615 WP_005609196.1 2037293..2037949(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae serovar 1 str. 4074]
MAISPKKFQYLKEIFSPLGEINFKSYFSYLGIFKDDTMFALYDHKNDRLYLRKSAQFYPDIIRTIPIHFLIDRRIGKQQS
HIFYLIPSSIIHNLHLYTHWILSAIEEYQTAKAKLISQNKNKIRLLPNLNINIERLLARIEIYTVDDLKNVGVINAFVKL
IMLGLEVTELLLFKLYAALEHKYIYMLSKQEKQSLLIEADLSLYNAGLRKRFAISQAN

Nucleotide

• Length: 657 bp

>NTDB_id=289221 APPSER1_RS09615 WP_005609196.1 2037293..2037949(-) (sxy/tfoX) [Actinobacillus pleuropneumoniae serovar 1 str. 4074]
ATGGCAATATCCCCAAAAAAGTTCCAATATCTTAAGGAGATTTTTAGTCCTCTTGGAGAAATTAACTTCAAAAGCTATTT
TTCTTACTTAGGAATATTTAAAGACGATACTATGTTCGCCCTCTATGATCATAAAAACGATCGATTATACTTAAGAAAAT
CCGCTCAATTTTATCCGGATATTATAAGAACAATACCGATACATTTTTTAATTGATCGTCGTATCGGTAAGCAACAATCT
CATATTTTTTATCTTATACCTTCTTCTATTATTCACAATCTTCATTTATATACTCATTGGATTCTCTCTGCTATCGAAGA
ATATCAAACTGCAAAGGCCAAATTGATTTCTCAAAATAAAAATAAAATTCGTCTGCTTCCCAATTTGAATATCAATATAG
AAAGATTATTGGCACGTATTGAGATTTATACCGTAGATGATTTAAAAAACGTAGGCGTGATTAATGCGTTTGTAAAACTG
ATAATGCTAGGCTTGGAAGTAACCGAATTACTCCTCTTCAAACTCTACGCTGCGCTCGAACATAAATATATCTATATGTT
ATCCAAGCAAGAAAAACAATCCCTATTAATTGAAGCCGATTTATCTCTCTATAACGCAGGCCTACGTAAACGCTTCGCTA
TCTCACAGGCTAACTAA

Domains

Predicted by InterproScan.

• TfoX C-terminal domain (TfoX_C) (120-196)

• TfoX N-terminal domain (TfoX_N) (13-107)

3D structure

• AlphaFold DB: A3N356

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sxy/tfoX	Actinobacillus pleuropneumoniae strain HS143	100	100	1
sxy/tfoX	Actinobacillus suis H91-0380	63.721	98.624	0.628
sxy/tfoX	Glaesserella parasuis strain SC1401	39.234	95.872	0.376