Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   D1J63_RS35525 Genome accession   NZ_CP034353
Coordinates   7842444..7843106 (+) Length   220 a.a.
NCBI ID   WP_125634748.1    Uniprot ID   -
Organism   Streptomyces sp. KPB2     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7837444..7848106
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  D1J63_RS35495 (D1J63_35495) - 7837455..7838222 (-) 768 WP_241235652.1 histidine phosphatase family protein -
  D1J63_RS35500 (D1J63_35500) - 7838219..7838431 (-) 213 WP_125634738.1 hypothetical protein -
  D1J63_RS35505 (D1J63_35505) - 7838579..7839568 (+) 990 WP_176156302.1 GlxA family transcriptional regulator -
  D1J63_RS35510 (D1J63_35510) - 7839702..7840340 (+) 639 WP_125634742.1 HD domain-containing protein -
  D1J63_RS35515 (D1J63_35515) - 7840701..7841078 (-) 378 WP_125634744.1 DUF6223 family protein -
  D1J63_RS35520 (D1J63_35520) - 7841320..7842447 (+) 1128 WP_125634746.1 histidine kinase -
  D1J63_RS35525 (D1J63_35525) vraR 7842444..7843106 (+) 663 WP_125634748.1 response regulator transcription factor Regulator
  D1J63_RS35530 (D1J63_35530) - 7843265..7843687 (+) 423 WP_125634751.1 VOC family protein -
  D1J63_RS36845 - 7844015..7844428 (+) 414 WP_164712659.1 hypothetical protein -
  D1J63_RS35540 (D1J63_35540) - 7845010..7845468 (+) 459 WP_241235653.1 MarR family transcriptional regulator -
  D1J63_RS35545 (D1J63_35545) - 7845465..7846913 (+) 1449 WP_125634753.1 MFS transporter -
  D1J63_RS35550 (D1J63_35550) - 7847055..7847330 (-) 276 WP_125634755.1 helix-turn-helix domain-containing protein -
  D1J63_RS35555 (D1J63_35555) - 7847802..7848095 (+) 294 WP_125634757.1 DUF1330 domain-containing protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23885.50 Da        Isoelectric Point: 4.8467

>NTDB_id=289136 D1J63_RS35525 WP_125634748.1 7842444..7843106(+) (vraR) [Streptomyces sp. KPB2]
MIRVLLVDDQPLIRSGFRALLELDDDIEVVAEAADGHEGLALVKEQLPDVVLIDIQMPVMDGIEATRRIAADPALAGVHV
VVLTNYGMDEYVFDALRAGAAGFLVKDIVPEDFLHAVRVAARGDALLAPAITRKLIDRYVTQPPSTRTRSGLEELTSRER
EAVALAAQGLSNDEIADRLVISPLTAKTHINRAMAKLHARDRAQLVVLAYESGLVAPRNS

Nucleotide


Download         Length: 663 bp        

>NTDB_id=289136 D1J63_RS35525 WP_125634748.1 7842444..7843106(+) (vraR) [Streptomyces sp. KPB2]
GTGATCCGGGTCCTGCTGGTCGACGACCAGCCGCTCATCCGCAGTGGCTTCCGCGCGCTGCTCGAACTCGACGACGACAT
CGAGGTCGTGGCCGAGGCCGCCGACGGCCACGAGGGCCTGGCGCTCGTCAAGGAGCAGTTGCCCGACGTCGTGCTCATCG
ACATCCAGATGCCCGTCATGGACGGCATCGAAGCGACCCGGCGCATCGCCGCGGATCCGGCCCTGGCCGGCGTACATGTC
GTCGTGCTGACCAACTACGGCATGGACGAGTACGTCTTCGACGCGCTGCGCGCCGGCGCCGCCGGGTTCCTGGTCAAAGA
CATCGTGCCGGAGGACTTCCTGCACGCCGTACGTGTTGCCGCCCGCGGCGACGCCCTGCTCGCGCCCGCGATCACCCGCA
AGCTCATCGACCGGTACGTCACCCAGCCGCCGTCCACCCGCACCCGCAGCGGCCTGGAGGAGCTGACCAGCCGCGAACGC
GAGGCCGTCGCCCTGGCTGCACAGGGCCTGTCCAACGATGAGATCGCCGACCGCCTGGTCATCAGCCCGTTGACCGCCAA
GACCCACATCAACCGTGCCATGGCCAAGCTCCACGCCCGCGACCGCGCCCAACTCGTGGTCCTCGCCTACGAGTCCGGCC
TGGTAGCCCCGCGCAACTCCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-117)

Bacterial regulatory proteins, luxR family (GerE)

(155-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.14

97.727

0.373

Multiple sequence alignment