Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   DBK22_RS01435 Genome accession   NZ_CP028961
Coordinates   268325..268981 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus velezensis strain SRCM102752     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 263325..273981
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DBK22_RS01410 (DBK22_00281) oppF 263854..264771 (+) 918 WP_015239568.1 oligopeptide ABC transporter ATP-binding protein OppF -
  DBK22_RS01415 (DBK22_00282) - 264878..266065 (+) 1188 WP_160241874.1 putative glycoside hydrolase -
  DBK22_RS01420 (DBK22_00283) - 266183..266761 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  DBK22_RS01425 (DBK22_00284) spx 266940..267335 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  DBK22_RS01430 (DBK22_00285) - 267393..268049 (-) 657 WP_160241875.1 TerC family protein -
  DBK22_RS19575 - 268232..268342 (+) 111 Protein_268 adaptor protein MecA -
  DBK22_RS01435 (DBK22_00286) mecA 268325..268981 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  DBK22_RS01440 (DBK22_00287) - 269132..270292 (+) 1161 WP_160241876.1 competence protein CoiA family protein -
  DBK22_RS01445 (DBK22_00288) pepF 270520..272349 (+) 1830 WP_094031915.1 oligoendopeptidase F Regulator
  DBK22_RS19580 (DBK22_00289) - 272387..272554 (-) 168 WP_003155026.1 hypothetical protein -
  DBK22_RS01450 (DBK22_00290) spxH 272840..273742 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=288967 DBK22_RS01435 WP_003155032.1 268325..268981(+) (mecA) [Bacillus velezensis strain SRCM102752]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=288967 DBK22_RS01435 WP_003155032.1 268325..268981(+) (mecA) [Bacillus velezensis strain SRCM102752]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATTTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment