Detailed information NTG0288285

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: C1A39_RS03235
• Genome accession: NZ_CP028896
• Coordinates: 602525..603526 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus strain CS5
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 597525..608526

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C1A39_RS03215 (C1A39_03270)	smpB	598632..599096 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
C1A39_RS03220 (C1A39_03275)	-	599250..600656 (+)	1407	WP_011680934.1	Cof-type HAD-IIB family hydrolase	-
C1A39_RS03225 (C1A39_03280)	-	600658..601023 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
C1A39_RS03230 (C1A39_03285)	-	601126..602211 (-)	1086	WP_011680935.1	Xaa-Pro peptidase family protein	-
C1A39_RS03235 (C1A39_03290)	ccpA	602525..603526 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
C1A39_RS03240 (C1A39_03295)	-	603585..603782 (+)	198	WP_014608125.1	hypothetical protein	-
C1A39_RS09855	-	603888..604112 (+)	225	WP_224102938.1	MmcQ/YjbR family DNA-binding protein	-
C1A39_RS03245 (C1A39_03300)	-	604113..604652 (+)	540	WP_011680936.1	hypothetical protein	-
C1A39_RS03250 (C1A39_03305)	-	604665..605780 (+)	1116	WP_011680937.1	glycerate kinase	-
C1A39_RS03255 (C1A39_03310)	-	605827..606282 (-)	456	WP_011680938.1	YueI family protein	-
C1A39_RS03260 (C1A39_03315)	eno	606491..607795 (+)	1305	WP_011680939.1	surface-displayed alpha-enolase	-
C1A39_RS03265 (C1A39_03320)	-	607947..608132 (-)	186	WP_011680940.1	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=288285 C1A39_RS03235 WP_004197422.1 602525..603526(+) (ccpA) [Streptococcus thermophilus strain CS5]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=288285 C1A39_RS03235 WP_004197422.1 602525..603526(+) (ccpA) [Streptococcus thermophilus strain CS5]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCAAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCCGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547