Detailed information NTG0285964

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: EHF39_RS09420
• Genome accession: NZ_CP033908
• Coordinates: 1831763..1832470 (-)
• Length: 235 a.a.
• NCBI ID: WP_028797165.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain RLGH
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1826763..1837470

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EHF39_RS09405 (EHF39_09405)	hexB	1827281..1829263 (-)	1983	WP_021299132.1	DNA mismatch repair endonuclease MutL	Machinery gene
EHF39_RS09410 (EHF39_09410)	-	1829358..1830509 (-)	1152	WP_003058754.1	site-specific integrase	-
EHF39_RS09415 (EHF39_09415)	-	1830758..1830901 (+)	144	WP_011185066.1	putative holin-like toxin	-
EHF39_RS09420 (EHF39_09420)	irvR	1831763..1832470 (-)	708	WP_028797165.1	S24 family peptidase	Regulator
EHF39_RS09425 (EHF39_09425)	-	1832684..1832890 (+)	207	WP_002992503.1	helix-turn-helix transcriptional regulator	-
EHF39_RS09430 (EHF39_09430)	-	1832924..1833097 (+)	174	Protein_1745	helix-turn-helix transcriptional regulator	-
EHF39_RS09435 (EHF39_09435)	-	1833145..1833552 (+)	408	WP_002992501.1	hypothetical protein	-
EHF39_RS10155	-	1833565..1833687 (+)	123	WP_011285272.1	hypothetical protein	-
EHF39_RS09440 (EHF39_09440)	-	1833970..1834491 (+)	522	WP_002992498.1	Rha family transcriptional regulator	-
EHF39_RS09445 (EHF39_09445)	-	1834739..1834912 (+)	174	WP_000132665.1	hypothetical protein	-
EHF39_RS09450 (EHF39_09450)	-	1835130..1835303 (+)	174	WP_000074663.1	hypothetical protein	-
EHF39_RS09455 (EHF39_09455)	-	1835465..1835896 (+)	432	WP_136302445.1	hypothetical protein	-
EHF39_RS09460 (EHF39_09460)	-	1835998..1836330 (+)	333	WP_011285276.1	hypothetical protein	-
EHF39_RS09465 (EHF39_09465)	-	1836330..1836521 (+)	192	WP_021340709.1	hypothetical protein	-
EHF39_RS09470 (EHF39_09470)	-	1836533..1836862 (+)	330	WP_003058810.1	hypothetical protein	-
EHF39_RS09475 (EHF39_09475)	-	1836865..1837137 (+)	273	WP_010922766.1	hypothetical protein	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 26437.43 Da
• Isoelectric Point: 4.3184

>NTDB_id=285964 EHF39_RS09420 WP_028797165.1 1831763..1832470(-) (irvR) [Streptococcus pyogenes strain RLGH]
MLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSNNIETNSNIIPSTLQKVTSTL
SQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIELPVDYDADFVIPVYGDSMEPE
YHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSDFRIIGEVIGSFTSKS

Nucleotide

• Length: 708 bp

>NTDB_id=285964 EHF39_RS09420 WP_028797165.1 1831763..1832470(-) (irvR) [Streptococcus pyogenes strain RLGH]
ATGCTTATGGCTAAAAAGAATATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTA
TGTTAAAGGTCGTTCACTCCCAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTG
ACCCCCGTTTTGATTCTAATAATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTA
TCTCAGCTAGAACACAAGCGACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGA
ACCACAAGCCACCTACTACACTTACAACTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTAC
AAGTAGAAACAATTGAATTACCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAA
TACCATTCTGGGGACTATGTATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGG
TGATGCTTATATCAAACAACTTGTTATAAACGATTCTGGAGCGTTTCTGCATAGTCTGAACGACAAGTATGACGATATAC
TCATAGATAGAGATAGTGATTTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (4-48)

• Peptidase S24-like (Peptidase_S24) (121-228)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	32.5	100	0.387