Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   NIS_RS07220 Genome accession   NC_009662
Coordinates   1354900..1356726 (+) Length   608 a.a.
NCBI ID   WP_012082714.1    Uniprot ID   A6Q4P2
Organism   Nitratiruptor sp. SB155-2     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1349900..1361726
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NIS_RS07200 (NIS_1339) guaA 1350082..1351632 (-) 1551 WP_012082710.1 glutamine-hydrolyzing GMP synthase -
  NIS_RS07205 (NIS_1340) nhaD 1351642..1352943 (-) 1302 WP_012082711.1 sodium:proton antiporter NhaD -
  NIS_RS07210 (NIS_1341) nadB 1352944..1354389 (-) 1446 WP_012082712.1 L-aspartate oxidase -
  NIS_RS07215 (NIS_1342) - 1354476..1354916 (+) 441 WP_012082713.1 hypothetical protein -
  NIS_RS07220 (NIS_1343) uvrC 1354900..1356726 (+) 1827 WP_012082714.1 excinuclease ABC subunit UvrC Machinery gene
  NIS_RS07225 (NIS_1344) - 1356807..1358648 (+) 1842 WP_012082715.1 Hpt domain-containing protein -
  NIS_RS07230 (NIS_1345) - 1358648..1359055 (+) 408 WP_012082716.1 sel1 repeat family protein -

Sequence

Protein


Download         Length: 608 a.a.        Molecular weight: 70746.99 Da        Isoelectric Point: 9.9656

>NTDB_id=28570 NIS_RS07220 WP_012082714.1 1354900..1356726(+) (uvrC) [Nitratiruptor sp. SB155-2]
MQRLIEKLQALPDAPGVYQYFDQNGRLLYVGKAKSLKKRVKSYFRFSPALTPAPNLSPRIFKMIHETKNLEYIVVESEND
ALILENSLIKQLKPKYNILLRDDKTYPYLYVDFNETFPRIKLTRKVIRGSNIRYFGPFPSAAKEIMDSLYELFPLVQKES
CIKGKKACLFYQMKRCLAPCEGKVTPKEYAQILDEAIFHLKDKQKLIEKLQNKMQEYAEQLRFEEAASLRDRIKKIESVQ
IQSGIDFAKMENLDIFAVEEDEKQAVLVRLFMREGKVISSSSTLYHIDKEKGFDRSEAYKRALLEFYQNQTPLTASRIIV
AHDFSDRDSVQNYLSKKFGKKITVQHPLRGEKRKIANLALLNAKELLKKRKNQNRIEDIIKSYFHLQHSPYRIEAFDNSH
ISGSNPVGAMVVYENGKFVKSDYRHYTLHHKDEYAQMKELLTRRCESFAKNPPPDLWIIDGGETLRQLAVDILQSHGVGI
DVIAIAKEKHDAKAHRAKGKAKDILYSAMGVHKLSPVDEKLLFFQKIRDEAHRFALQFHRQKRQKESKLVELLQIDGIGE
ATLKKLLHFYGTFERIKKSDFEELKQLVGEKTAQKILEHFSKHDLNLL

Nucleotide


Download         Length: 1827 bp        

>NTDB_id=28570 NIS_RS07220 WP_012082714.1 1354900..1356726(+) (uvrC) [Nitratiruptor sp. SB155-2]
ATGCAAAGACTCATTGAAAAGTTACAAGCATTACCCGATGCTCCTGGCGTGTACCAATATTTTGATCAAAATGGGCGCCT
GCTGTATGTCGGCAAAGCAAAAAGCCTCAAAAAAAGGGTGAAAAGCTATTTTCGATTTTCACCTGCACTCACTCCGGCAC
CAAATCTCTCTCCAAGAATCTTTAAAATGATTCATGAAACAAAAAATTTGGAATATATTGTTGTCGAGAGCGAAAACGAT
GCGCTTATATTGGAAAACTCTCTTATCAAACAGCTTAAACCAAAATACAATATCTTGCTGCGGGATGATAAAACTTATCC
CTATCTCTACGTAGATTTCAATGAAACTTTTCCTCGAATCAAGCTGACACGAAAAGTTATCCGGGGAAGCAATATCAGAT
ATTTTGGTCCTTTTCCATCTGCGGCAAAAGAGATTATGGACTCTTTGTACGAACTCTTTCCTCTCGTTCAAAAAGAGAGT
TGCATCAAAGGGAAAAAAGCGTGTCTTTTTTATCAGATGAAGAGATGTTTGGCACCATGTGAAGGCAAAGTCACTCCAAA
GGAGTATGCACAAATCTTAGATGAAGCGATTTTTCATCTCAAAGATAAACAGAAACTTATTGAAAAACTGCAAAACAAGA
TGCAGGAGTATGCTGAACAACTGCGATTTGAAGAAGCTGCCAGTCTTAGAGACAGAATAAAAAAAATAGAATCTGTACAG
ATCCAAAGCGGGATCGATTTTGCAAAAATGGAAAATCTCGATATTTTTGCTGTCGAAGAGGATGAGAAGCAAGCGGTGTT
GGTGCGACTTTTTATGCGGGAAGGGAAAGTCATTTCAAGCAGTTCGACACTCTACCACATCGATAAAGAGAAGGGCTTTG
ATAGATCCGAAGCGTACAAAAGAGCCCTTTTAGAGTTTTATCAAAACCAAACGCCTCTGACAGCCTCACGAATCATCGTA
GCACACGATTTTAGCGATAGAGACTCTGTCCAAAACTATTTGAGTAAAAAATTTGGTAAAAAGATCACCGTTCAACATCC
TTTACGGGGAGAGAAACGAAAAATCGCCAATTTGGCACTGCTCAACGCTAAAGAGCTTTTGAAAAAGAGAAAGAATCAAA
ATCGTATCGAAGATATAATCAAATCCTATTTTCATCTACAACACTCCCCGTACAGAATTGAAGCATTTGACAATTCCCAT
ATCAGTGGCTCCAATCCTGTTGGTGCGATGGTCGTATATGAAAATGGCAAGTTTGTCAAATCCGATTATAGACACTATAC
GCTCCATCATAAAGATGAATATGCCCAGATGAAAGAGCTCCTTACAAGAAGATGTGAAAGTTTTGCAAAAAATCCGCCAC
CTGACTTGTGGATAATTGATGGGGGAGAAACATTAAGACAACTAGCGGTAGATATCCTGCAGAGCCATGGTGTGGGTATA
GATGTTATCGCCATAGCAAAAGAGAAACACGATGCGAAGGCGCATCGCGCCAAAGGTAAGGCGAAAGATATTCTCTATAG
CGCCATGGGCGTTCATAAACTTTCACCAGTCGATGAAAAGTTACTCTTTTTTCAAAAAATAAGGGACGAAGCACATAGAT
TTGCTTTACAGTTTCATAGACAAAAACGACAAAAAGAGTCTAAATTAGTAGAGTTACTACAAATCGATGGTATCGGTGAA
GCTACACTGAAAAAATTGCTTCATTTTTACGGCACCTTTGAAAGGATTAAAAAAAGCGATTTTGAAGAATTGAAACAGCT
CGTGGGAGAAAAAACAGCGCAAAAGATTCTCGAACATTTCTCTAAGCATGATTTAAATTTGTTATGA

Domains

Predicted by InterproScan.

UvrB/uvrC motif (UVR)

(205-238)

GIY-YIG catalytic domain (GIY-YIG)

(16-97)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(382-535)

Helix-hairpin-helix domain (HHH_5)

(551-599)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A6Q4P2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

50.085

96.875

0.485

Multiple sequence alignment